Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895798918> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2895798918 abstract "Objective This article reviews the role of miRNAs in promoting insulin sensitivity, controlling insulin synthesis, and regulating insulin resistance in hypoxia exercise, and discusses the relationship between miRNAs and glucose metabolism, and the mechanism of hypoxia-induced regulation of miRNAs in glucose metabolism. It provides a theoretical basis for better research on the prevention and treatment of disorders of glucose metabolism.
 Methods This paper uses the literature data method, collects a large number of documents and cites more than 90 articles for comprehensive statistical analysis to write this article, which provides researchers with relevant research directions.
 Results Studies have shown that miRNAs such as miR-138, miR-26b, miR-27a, miR-122, miR-802 and miR-143 have regulatory effects on obesity; some miRNAs such as miR-128, miR-7, miR-25, miR -92a, miR-375 and miR-15 family (miR-15a and miR-15b) and other miRNAs play an important role in regulating glycolipid metabolism, thereby maintaining a stable state of glycolipid metabolism. Expressions such as miR-802 and miR-143 are up-regulated in the liver of obese patients, resulting in impaired glucose tolerance.
 Conclusions By regulating the expression of target genes and maintaining the homeostasis of glucose metabolism, miRNAs can effectively improve or prevent obesity and disorders of glucose metabolism such as type 2 diabetes. Current studies have shown that miRNAs affect glucose metabolism from insulin sensitivity, insulin synthesis and insulin resistance. At the same time, studies have shown that exercise intervention can effectively improve glucose metabolism. However, the research on the metabolism of miRNAs in glucose metabolism during hypoxia is still insufficient. It is for further study. Studying the mechanism of the effects of miRNAs on glucose metabolism in hypoxic exercise can not only provide a theoretical basis for scientific hypoglycemic and weight control, but also can be used as an intervention for the prevention and control of diseases related to glucose metabolism disorders. In the future, drugs can regulate the expression of miRNAs, thereby providing a new therapeutic approach for the treatment of diseases caused by abnormal glucose and lipid metabolism." @default.
- W2895798918 created "2018-10-26" @default.
- W2895798918 creator A5090503888 @default.
- W2895798918 date "2018-10-04" @default.
- W2895798918 modified "2023-09-25" @default.
- W2895798918 title "PO-029 Advances in research on hypoxia-mediated miRNAs affecting glucose metabolism" @default.
- W2895798918 doi "https://doi.org/10.14428/ebr.v1i3.9933" @default.
- W2895798918 hasPublicationYear "2018" @default.
- W2895798918 type Work @default.
- W2895798918 sameAs 2895798918 @default.
- W2895798918 citedByCount "0" @default.
- W2895798918 crossrefType "journal-article" @default.
- W2895798918 hasAuthorship W2895798918A5090503888 @default.
- W2895798918 hasBestOaLocation W28957989181 @default.
- W2895798918 hasConcept C104317684 @default.
- W2895798918 hasConcept C134018914 @default.
- W2895798918 hasConcept C145059251 @default.
- W2895798918 hasConcept C17093226 @default.
- W2895798918 hasConcept C2777391703 @default.
- W2895798918 hasConcept C2777866211 @default.
- W2895798918 hasConcept C2779306644 @default.
- W2895798918 hasConcept C3018667095 @default.
- W2895798918 hasConcept C55493867 @default.
- W2895798918 hasConcept C60644358 @default.
- W2895798918 hasConcept C62231903 @default.
- W2895798918 hasConcept C86803240 @default.
- W2895798918 hasConceptScore W2895798918C104317684 @default.
- W2895798918 hasConceptScore W2895798918C134018914 @default.
- W2895798918 hasConceptScore W2895798918C145059251 @default.
- W2895798918 hasConceptScore W2895798918C17093226 @default.
- W2895798918 hasConceptScore W2895798918C2777391703 @default.
- W2895798918 hasConceptScore W2895798918C2777866211 @default.
- W2895798918 hasConceptScore W2895798918C2779306644 @default.
- W2895798918 hasConceptScore W2895798918C3018667095 @default.
- W2895798918 hasConceptScore W2895798918C55493867 @default.
- W2895798918 hasConceptScore W2895798918C60644358 @default.
- W2895798918 hasConceptScore W2895798918C62231903 @default.
- W2895798918 hasConceptScore W2895798918C86803240 @default.
- W2895798918 hasLocation W28957989181 @default.
- W2895798918 hasOpenAccess W2895798918 @default.
- W2895798918 hasPrimaryLocation W28957989181 @default.
- W2895798918 hasRelatedWork W1929556414 @default.
- W2895798918 hasRelatedWork W1944402090 @default.
- W2895798918 hasRelatedWork W1997386949 @default.
- W2895798918 hasRelatedWork W2016476680 @default.
- W2895798918 hasRelatedWork W2042714431 @default.
- W2895798918 hasRelatedWork W2067336382 @default.
- W2895798918 hasRelatedWork W2081725090 @default.
- W2895798918 hasRelatedWork W2165856885 @default.
- W2895798918 hasRelatedWork W2306895977 @default.
- W2895798918 hasRelatedWork W2359575844 @default.
- W2895798918 hasRelatedWork W2361979788 @default.
- W2895798918 hasRelatedWork W2602590693 @default.
- W2895798918 hasRelatedWork W2770317202 @default.
- W2895798918 hasRelatedWork W2784039556 @default.
- W2895798918 hasRelatedWork W2891502735 @default.
- W2895798918 hasRelatedWork W3028766808 @default.
- W2895798918 hasRelatedWork W3083214295 @default.
- W2895798918 hasRelatedWork W3106255581 @default.
- W2895798918 hasRelatedWork W3185653150 @default.
- W2895798918 hasRelatedWork W3188331218 @default.
- W2895798918 isParatext "false" @default.
- W2895798918 isRetracted "false" @default.
- W2895798918 magId "2895798918" @default.
- W2895798918 workType "article" @default.