Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895815632> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2895815632 endingPage "2903" @default.
- W2895815632 startingPage "2897" @default.
- W2895815632 abstract "Background: Previous studies have assessed associations between single nucleotide polymorphisms (SNPs) of the Partner and localizer of BRCA2 (PALB2) gene and risk of breast cancer. However, the results of these studies are not consistent. Materials and Methods: We designed a meta-analysis to obtain a more reliable appraisal of the association between SNPs in the PALB2 gene and the susceptibility to breast cancer. We searched PubMed, Google scholar and Embase databases and selected six studies with sufficient data to estimate the pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: Statistical analyses showed that the rs120963 was associated with breast cancer risk in allelic (OR (95% CI) = 1.33 (1.18-1.49)), homozygous (OR (95% CI) = 1.74 (1.31-2.32)), dominant (OR (95% CI) = 1.42 (1.22, 1.65)) and recessive (OR (95% CI) = 1.54 (1.17, 2.03)) models. The rs249954 and rs16940342 were associated with breast cancer risk in allelic (OR (95% CI) = 1.13 (1.04, 1.23) and 1.12 (1.01, 1.24) respectively) and dominant (OR (95% CI) = 1.23 (1.09, 1.39) and 1.18 (1.04, 1.33) respectively) models. The rs249935 and rs447529 SNPs were associated with breast cancer in homozygous (OR (95% CI) = 0.67 (0.46, 0.97) and 0.51 (0.30, 0.89) respectively) and recessive (OR (95% CI) = 0.65 (0.45, 0.95) and 0.51 (0.30, 0.88) respectively) models. Conclusions: The current meta-analysis shows the associations between five SNPs of PALB2 and breast cancer risk and confirms the results of previous studies regarding the role of this gene in the pathogenesis of breast cancer" @default.
- W2895815632 created "2018-10-26" @default.
- W2895815632 creator A5010828029 @default.
- W2895815632 creator A5070880476 @default.
- W2895815632 creator A5083975126 @default.
- W2895815632 date "2018-10-26" @default.
- W2895815632 modified "2023-09-23" @default.
- W2895815632 title "Meta-Analysis of Association between PALB2 Polymorphisms and Breast Cancer" @default.
- W2895815632 cites W1984239825 @default.
- W2895815632 cites W2002150942 @default.
- W2895815632 cites W2023353541 @default.
- W2895815632 cites W2034702779 @default.
- W2895815632 cites W2038992163 @default.
- W2895815632 cites W2085502397 @default.
- W2895815632 cites W2088535920 @default.
- W2895815632 cites W2090139929 @default.
- W2895815632 cites W2116475791 @default.
- W2895815632 cites W2122194435 @default.
- W2895815632 cites W2128700722 @default.
- W2895815632 cites W2130118233 @default.
- W2895815632 cites W2139253193 @default.
- W2895815632 cites W2157570211 @default.
- W2895815632 cites W2163183874 @default.
- W2895815632 cites W2194014097 @default.
- W2895815632 cites W2205277042 @default.
- W2895815632 cites W2298845854 @default.
- W2895815632 cites W2485485377 @default.
- W2895815632 cites W4210609636 @default.
- W2895815632 doi "https://doi.org/10.22034/apjcp.2018.19.10.2897" @default.
- W2895815632 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6291065" @default.
- W2895815632 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30362319" @default.
- W2895815632 hasPublicationYear "2018" @default.
- W2895815632 type Work @default.
- W2895815632 sameAs 2895815632 @default.
- W2895815632 citedByCount "1" @default.
- W2895815632 countsByYear W28958156322018 @default.
- W2895815632 crossrefType "journal-article" @default.
- W2895815632 hasAuthorship W2895815632A5010828029 @default.
- W2895815632 hasAuthorship W2895815632A5070880476 @default.
- W2895815632 hasAuthorship W2895815632A5083975126 @default.
- W2895815632 hasConcept C104317684 @default.
- W2895815632 hasConcept C121608353 @default.
- W2895815632 hasConcept C126322002 @default.
- W2895815632 hasConcept C13514818 @default.
- W2895815632 hasConcept C135763542 @default.
- W2895815632 hasConcept C143998085 @default.
- W2895815632 hasConcept C153209595 @default.
- W2895815632 hasConcept C156957248 @default.
- W2895815632 hasConcept C180754005 @default.
- W2895815632 hasConcept C2778144015 @default.
- W2895815632 hasConcept C44249647 @default.
- W2895815632 hasConcept C501734568 @default.
- W2895815632 hasConcept C530470458 @default.
- W2895815632 hasConcept C54355233 @default.
- W2895815632 hasConcept C71924100 @default.
- W2895815632 hasConcept C86803240 @default.
- W2895815632 hasConcept C95190672 @default.
- W2895815632 hasConceptScore W2895815632C104317684 @default.
- W2895815632 hasConceptScore W2895815632C121608353 @default.
- W2895815632 hasConceptScore W2895815632C126322002 @default.
- W2895815632 hasConceptScore W2895815632C13514818 @default.
- W2895815632 hasConceptScore W2895815632C135763542 @default.
- W2895815632 hasConceptScore W2895815632C143998085 @default.
- W2895815632 hasConceptScore W2895815632C153209595 @default.
- W2895815632 hasConceptScore W2895815632C156957248 @default.
- W2895815632 hasConceptScore W2895815632C180754005 @default.
- W2895815632 hasConceptScore W2895815632C2778144015 @default.
- W2895815632 hasConceptScore W2895815632C44249647 @default.
- W2895815632 hasConceptScore W2895815632C501734568 @default.
- W2895815632 hasConceptScore W2895815632C530470458 @default.
- W2895815632 hasConceptScore W2895815632C54355233 @default.
- W2895815632 hasConceptScore W2895815632C71924100 @default.
- W2895815632 hasConceptScore W2895815632C86803240 @default.
- W2895815632 hasConceptScore W2895815632C95190672 @default.
- W2895815632 hasIssue "10" @default.
- W2895815632 hasLocation W28958156321 @default.
- W2895815632 hasOpenAccess W2895815632 @default.
- W2895815632 hasPrimaryLocation W28958156321 @default.
- W2895815632 hasRelatedWork W1996753309 @default.
- W2895815632 hasRelatedWork W2023731824 @default.
- W2895815632 hasRelatedWork W2062034310 @default.
- W2895815632 hasRelatedWork W2082392604 @default.
- W2895815632 hasRelatedWork W2107074164 @default.
- W2895815632 hasRelatedWork W2150701277 @default.
- W2895815632 hasRelatedWork W2256119029 @default.
- W2895815632 hasRelatedWork W2286371484 @default.
- W2895815632 hasRelatedWork W2780508286 @default.
- W2895815632 hasRelatedWork W3123470697 @default.
- W2895815632 hasVolume "19" @default.
- W2895815632 isParatext "false" @default.
- W2895815632 isRetracted "false" @default.
- W2895815632 magId "2895815632" @default.
- W2895815632 workType "article" @default.