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• W2895826271 abstract "Disease modification remains a major unmet need in Parkinson's disease (PD) therapeutics. Despite multiple attempts, not a single study has yet been successful, perhaps due to our incomplete understanding of the underlying disease mechanisms. Genetic and epidemiologic studies of the last decade have substantially increased our comprehension of the etiology of PD. Once considered a pure sporadic disease, the discovery of familial mutations provided the initial paradigm shift and it is now widely accepted that PD has a substantial genetic component. These genetic discoveries have allowed the development of novel therapeutics aimed at halting or slowing the underlying disease process, rather than just ameliorating symptoms. Here, we discuss the latest advances in therapeutics based on three genetic discoveries (SNCA, LRRK2 and GBA) that are currently reaching the clinical arena and outline the challenges of therapeutic development of genetically targeted therapeutics." @default.
• W2895826271 created "2018-10-26" @default.
• W2895826271 creator A5015630245 @default.
• W2895826271 creator A5070129663 @default.
• W2895826271 date "2019-02-01" @default.
• W2895826271 modified "2023-10-12" @default.
• W2895826271 title "New Era in disease modification in Parkinson's disease: Review of genetically targeted therapeutics" @default.
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• W2895826271 cites W1527671059 @default.
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• W2895826271 cites W1965095016 @default.
• W2895826271 cites W1970687029 @default.
• W2895826271 cites W1982224533 @default.
• W2895826271 cites W1988494453 @default.
• W2895826271 cites W1992365739 @default.
• W2895826271 cites W1997935934 @default.
• W2895826271 cites W1999221820 @default.
• W2895826271 cites W1999702935 @default.
• W2895826271 cites W2006380359 @default.
• W2895826271 cites W2017715011 @default.
• W2895826271 cites W2018816152 @default.
• W2895826271 cites W2020167843 @default.
• W2895826271 cites W2031365272 @default.
• W2895826271 cites W2040696002 @default.
• W2895826271 cites W2044407202 @default.
• W2895826271 cites W2050647292 @default.
• W2895826271 cites W2053206193 @default.
• W2895826271 cites W2057075939 @default.
• W2895826271 cites W2063049494 @default.
• W2895826271 cites W2063127941 @default.
• W2895826271 cites W2079378641 @default.
• W2895826271 cites W2086701255 @default.
• W2895826271 cites W2089522371 @default.
• W2895826271 cites W2096643590 @default.
• W2895826271 cites W2100300726 @default.
• W2895826271 cites W2131476886 @default.
• W2895826271 cites W2133710289 @default.
• W2895826271 cites W2137300912 @default.
• W2895826271 cites W2148641246 @default.
• W2895826271 cites W2150656456 @default.
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• W2895826271 cites W2343290709 @default.
• W2895826271 cites W2462137239 @default.
• W2895826271 cites W2464353788 @default.
• W2895826271 cites W2495228129 @default.
• W2895826271 cites W2508840882 @default.
• W2895826271 cites W2513452411 @default.
• W2895826271 cites W2523238466 @default.
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• W2895826271 cites W2753292637 @default.
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• W2895826271 cites W2763748630 @default.
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• W2895826271 cites W2765638828 @default.
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• W2895826271 doi "https://doi.org/10.1016/j.parkreldis.2018.10.025" @default.
• W2895826271 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30391183" @default.
• W2895826271 hasPublicationYear "2019" @default.
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