FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895827187> ?p ?o ?g. }

• W2895827187 endingPage "1506" @default.
• W2895827187 startingPage "1495" @default.
• W2895827187 abstract "Type 2 Diabetes Mellitus (T2DM) is very common metabolic disorder affecting people of all age groups. The change in life style and environmental factors are the considerable factors which are involved in the development of the disorder. The different parts of medicinal plants vary in their composition of bioactive compounds. There are reports on antidiabetic activity of C. auriculata L. flower and leaves. Traditionally bud of C. auriculata L. is used to treat diabetes rather than flower. This study aims to explore the antidiabetic efficiency of bud and flower and to identify the differential composition of phycompounds present in bud and flower parts of C. auriculata L. The compounds present in the bud and flower parts were identified using LC-ESI/MS analysis. Antidiabetic activity of C. auriculata L. bud and flower parts was studied in high fat diet (HFD) and streptozotocin (STZ) induced diabetic rats. During which parameters such as feed intake, water intake, and body weight were monitored. After 21 days of the study, blood parameters like insulin, glucose, lipid profile, hepatic function test, renal function test and oxidative stress markers were analysed. Real time PCR was done to monitor the expression of IRS2 and GRIA2 genes. The LC-ESI/MS analysis showed the presence of various phenolics and flavonoid compounds specific to bud and flower parts. The antidiabetic activity results showed that the animal treated with C. auriculata L. bud ethanol extract (CABE500) could better reverse and control the progression of the disease compared to the flower ethanol extract. The gene expression studies revealed that regulation of IRS2 gene occurred in bud but not in flower extract treated animal livers and no differential expression of GRIA2 gene in all the experimental groups. C. auriculata L. bud extract can potentially better control the diabetes compared to the flower extract." @default.
• W2895827187 created "2018-10-26" @default.
• W2895827187 creator A5008797265 @default.
• W2895827187 creator A5032529325 @default.
• W2895827187 creator A5040491202 @default.
• W2895827187 creator A5042085943 @default.
• W2895827187 creator A5064337358 @default.
• W2895827187 creator A5070324709 @default.
• W2895827187 creator A5081187657 @default.
• W2895827187 date "2018-12-01" @default.
• W2895827187 modified "2023-10-14" @default.
• W2895827187 title "Evaluation of antidiabetic activity of bud and flower of Avaram Senna (Cassia auriculata L.) In high fat diet and streptozotocin induced diabetic rats" @default.
• W2895827187 cites W1575245978 @default.
• W2895827187 cites W1903078185 @default.
• W2895827187 cites W1966621383 @default.
• W2895827187 cites W1971432941 @default.
• W2895827187 cites W1972323440 @default.
• W2895827187 cites W1973794425 @default.
• W2895827187 cites W1976536739 @default.
• W2895827187 cites W1977948871 @default.
• W2895827187 cites W1992725304 @default.
• W2895827187 cites W2002909438 @default.
• W2895827187 cites W2008197682 @default.
• W2895827187 cites W2012991711 @default.
• W2895827187 cites W2022022835 @default.
• W2895827187 cites W2022138253 @default.
• W2895827187 cites W2024352719 @default.
• W2895827187 cites W2028165126 @default.
• W2895827187 cites W2031596649 @default.
• W2895827187 cites W2031733287 @default.
• W2895827187 cites W2032729761 @default.
• W2895827187 cites W2039762060 @default.
• W2895827187 cites W2042137103 @default.
• W2895827187 cites W2043533197 @default.
• W2895827187 cites W2048039240 @default.
• W2895827187 cites W2048601019 @default.
• W2895827187 cites W2058240461 @default.
• W2895827187 cites W2059628066 @default.
• W2895827187 cites W2067231962 @default.
• W2895827187 cites W2069132215 @default.
• W2895827187 cites W2077083673 @default.
• W2895827187 cites W2080786974 @default.
• W2895827187 cites W2086434878 @default.
• W2895827187 cites W2088765923 @default.
• W2895827187 cites W2089916479 @default.
• W2895827187 cites W2130839195 @default.
• W2895827187 cites W2153977812 @default.
• W2895827187 cites W2158399925 @default.
• W2895827187 cites W2159744672 @default.
• W2895827187 cites W2165216197 @default.
• W2895827187 cites W2168209047 @default.
• W2895827187 cites W2172155425 @default.
• W2895827187 cites W2182327731 @default.
• W2895827187 cites W2193975244 @default.
• W2895827187 cites W2313809187 @default.
• W2895827187 cites W2316328268 @default.
• W2895827187 cites W2321546906 @default.
• W2895827187 cites W2495483957 @default.
• W2895827187 cites W2585273411 @default.
• W2895827187 cites W2611629086 @default.
• W2895827187 cites W2618048812 @default.
• W2895827187 cites W2663397170 @default.
• W2895827187 cites W2752737313 @default.
• W2895827187 cites W2752941294 @default.
• W2895827187 cites W2754235429 @default.
• W2895827187 doi "https://doi.org/10.1016/j.biopha.2018.10.007" @default.
• W2895827187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30372851" @default.
• W2895827187 hasPublicationYear "2018" @default.
• W2895827187 type Work @default.
• W2895827187 sameAs 2895827187 @default.
• W2895827187 citedByCount "34" @default.
• W2895827187 countsByYear W28958271872019 @default.
• W2895827187 countsByYear W28958271872020 @default.
• W2895827187 countsByYear W28958271872021 @default.
• W2895827187 countsByYear W28958271872022 @default.
• W2895827187 countsByYear W28958271872023 @default.
• W2895827187 crossrefType "journal-article" @default.
• W2895827187 hasAuthorship W2895827187A5008797265 @default.
• W2895827187 hasAuthorship W2895827187A5032529325 @default.
• W2895827187 hasAuthorship W2895827187A5040491202 @default.
• W2895827187 hasAuthorship W2895827187A5042085943 @default.
• W2895827187 hasAuthorship W2895827187A5064337358 @default.
• W2895827187 hasAuthorship W2895827187A5070324709 @default.
• W2895827187 hasAuthorship W2895827187A5081187657 @default.
• W2895827187 hasBestOaLocation W28958271871 @default.
• W2895827187 hasConcept C134018914 @default.
• W2895827187 hasConcept C142724271 @default.
• W2895827187 hasConcept C188947578 @default.
• W2895827187 hasConcept C204787440 @default.
• W2895827187 hasConcept C2775939860 @default.
• W2895827187 hasConcept C2779280383 @default.
• W2895827187 hasConcept C2779306644 @default.
• W2895827187 hasConcept C555293320 @default.
• W2895827187 hasConcept C556039675 @default.
• W2895827187 hasConcept C59822182 @default.
• W2895827187 hasConcept C71924100 @default.
• W2895827187 hasConcept C86803240 @default.
• W2895827187 hasConceptScore W2895827187C134018914 @default.

• next