FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895827744> ?p ?o ?g. }

• W2895827744 endingPage "1137" @default.
• W2895827744 startingPage "1128" @default.
• W2895827744 abstract "Previous anatomical and behavioral studies have shown that melanin-concentrating hormone is involved in the modulation of emotional states. However, little is known about brain regions other than the dorsal raphe nucleus that relate the melanin-concentrating hormone-ergic system to depressive states. Numerous studies have shown that the locus coeruleus is involved in the regulation of depression and sleep. Although direct physiological evidence is lacking, previous studies suggest that melanin-concentrating hormone release in the locus coeruleus decreases neuronal discharge. However, remaining unclear is whether the melanin-concentrating hormone-ergic system in the locus coeruleus is related to depressive-like behavior.We treated rats with an intra-locus coeruleus injection of melanin-concentrating hormone, intracerebroventricular injection of melanin-concentrating hormone, or chronic subcutaneous injections of corticosterone to induce different depressive-like phenotypes. We then assessed the effects of the melanin-concentrating hormone receptor 1 antagonist SNAP-94847 on depressive-like behavior in the forced swim test and the sucrose preference test.The intra-locus coeruleus and intracerebroventricular injections of melanin-concentrating hormone and chronic injections of corticosterone increased immobility time in the forced swim test and decreased sucrose preference in the sucrose preference test. All these depressive-like behaviors were reversed by an intra-locus coeruleus microinjection of SNAP-94847.These results suggest that the melanin-concentrating hormone-ergic system in the locus coeruleus might play an important role in the regulation of depressive-like behavior." @default.
• W2895827744 created "2018-10-26" @default.
• W2895827744 creator A5008596951 @default.
• W2895827744 creator A5011740024 @default.
• W2895827744 creator A5013015027 @default.
• W2895827744 creator A5014028115 @default.
• W2895827744 creator A5017122859 @default.
• W2895827744 creator A5026299521 @default.
• W2895827744 creator A5063512998 @default.
• W2895827744 creator A5086009238 @default.
• W2895827744 date "2018-10-18" @default.
• W2895827744 modified "2023-10-16" @default.
• W2895827744 title "Melanin-Concentrating Hormone (MCH) and MCH-R1 in the Locus Coeruleus May Be Involved in the Regulation of Depressive-Like Behavior" @default.
• W2895827744 cites W1495904497 @default.
• W2895827744 cites W1621566533 @default.
• W2895827744 cites W166672103 @default.
• W2895827744 cites W1793127045 @default.
• W2895827744 cites W1976845544 @default.
• W2895827744 cites W1978082185 @default.
• W2895827744 cites W1980603718 @default.
• W2895827744 cites W1983627599 @default.
• W2895827744 cites W1989830384 @default.
• W2895827744 cites W2000140223 @default.
• W2895827744 cites W2000591684 @default.
• W2895827744 cites W2000875771 @default.
• W2895827744 cites W2003094191 @default.
• W2895827744 cites W2003342221 @default.
• W2895827744 cites W2011580879 @default.
• W2895827744 cites W2013559494 @default.
• W2895827744 cites W2017293874 @default.
• W2895827744 cites W2027429673 @default.
• W2895827744 cites W2037078465 @default.
• W2895827744 cites W2037666846 @default.
• W2895827744 cites W2050923936 @default.
• W2895827744 cites W2056585088 @default.
• W2895827744 cites W2058163812 @default.
• W2895827744 cites W2063736752 @default.
• W2895827744 cites W2064380676 @default.
• W2895827744 cites W2064605776 @default.
• W2895827744 cites W2067136906 @default.
• W2895827744 cites W2076677696 @default.
• W2895827744 cites W2079230902 @default.
• W2895827744 cites W2083217982 @default.
• W2895827744 cites W2091064555 @default.
• W2895827744 cites W2092177735 @default.
• W2895827744 cites W2101334425 @default.
• W2895827744 cites W2106595454 @default.
• W2895827744 cites W2110159815 @default.
• W2895827744 cites W2125654139 @default.
• W2895827744 cites W2144574820 @default.
• W2895827744 cites W2149154629 @default.
• W2895827744 cites W2323040745 @default.
• W2895827744 cites W2547552480 @default.
• W2895827744 cites W2728917152 @default.
• W2895827744 cites W2762806555 @default.
• W2895827744 cites W2807355483 @default.
• W2895827744 cites W4210980066 @default.
• W2895827744 doi "https://doi.org/10.1093/ijnp/pyy088" @default.
• W2895827744 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6276047" @default.
• W2895827744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30335150" @default.
• W2895827744 hasPublicationYear "2018" @default.
• W2895827744 type Work @default.
• W2895827744 sameAs 2895827744 @default.
• W2895827744 citedByCount "16" @default.
• W2895827744 countsByYear W28958277442019 @default.
• W2895827744 countsByYear W28958277442020 @default.
• W2895827744 countsByYear W28958277442021 @default.
• W2895827744 countsByYear W28958277442022 @default.
• W2895827744 countsByYear W28958277442023 @default.
• W2895827744 crossrefType "journal-article" @default.
• W2895827744 hasAuthorship W2895827744A5008596951 @default.
• W2895827744 hasAuthorship W2895827744A5011740024 @default.
• W2895827744 hasAuthorship W2895827744A5013015027 @default.
• W2895827744 hasAuthorship W2895827744A5014028115 @default.
• W2895827744 hasAuthorship W2895827744A5017122859 @default.
• W2895827744 hasAuthorship W2895827744A5026299521 @default.
• W2895827744 hasAuthorship W2895827744A5063512998 @default.
• W2895827744 hasAuthorship W2895827744A5086009238 @default.
• W2895827744 hasBestOaLocation W28958277441 @default.
• W2895827744 hasConcept C118303440 @default.
• W2895827744 hasConcept C126322002 @default.
• W2895827744 hasConcept C134018914 @default.
• W2895827744 hasConcept C136569192 @default.
• W2895827744 hasConcept C15744967 @default.
• W2895827744 hasConcept C169760540 @default.
• W2895827744 hasConcept C170493617 @default.
• W2895827744 hasConcept C185592680 @default.
• W2895827744 hasConcept C2776632733 @default.
• W2895827744 hasConcept C2776885963 @default.
• W2895827744 hasConcept C2778468602 @default.
• W2895827744 hasConcept C2779177272 @default.
• W2895827744 hasConcept C2780352252 @default.
• W2895827744 hasConcept C2781161787 @default.
• W2895827744 hasConcept C529278444 @default.
• W2895827744 hasConcept C71315377 @default.
• W2895827744 hasConcept C71924100 @default.
• W2895827744 hasConcept C8439214 @default.
• W2895827744 hasConcept C86803240 @default.

• next