FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895872185> ?p ?o ?g. }

• W2895872185 endingPage "1242" @default.
• W2895872185 startingPage "1236" @default.
• W2895872185 abstract "Autonomic support of blood pressure increases with age in humans. Large differences exist in the dose of trimethaphan (TMP) required for ganglionic blockade in young and older women. We asked whether differences in the dose of TMP required to achieve ganglionic blockade are because of differences in the relative contributions of the sympathetic and parasympathetic nervous system in control of blood pressure with age. Muscle sympathetic nerve activity (microneurography, peroneal nerve), heart rate (HR), and blood pressure were recorded before and during incremental doses of TMP camsylate until ganglionic blockade was achieved (absence of muscle sympathetic nerve activity and <5-bpm increase in HR during a valsalva maneuver; final TMP dose, 1–7 mg/min). HR variability was analyzed from the ECG waveform (WinCPRS). The dose of TMP required to achieve ganglionic blockade is positively related to basal HR variability, where women with high HR variability require a higher dose of TMP to achieve ganglionic blockade. In contrast, baseline muscle sympathetic nerve activity is inversely related with the dose of TMP required to achieve ganglionic blockade, such that women with high basal muscle sympathetic nerve activity required a lower dose of TMP. As such, the change in HR with ganglionic blockade was positively related, and the change in mean arterial pressure was inversely related, with the dose of TMP required to achieve ganglionic blockade. These data suggest loss of parasympathetic tone and increased sympathetic tone with aging contribute to the increase in blood pressure with age in women and dictate the dose of TMP that is necessary to achieve ganglionic blockade." @default.
• W2895872185 created "2018-10-26" @default.
• W2895872185 creator A5003362911 @default.
• W2895872185 creator A5029721543 @default.
• W2895872185 creator A5031480179 @default.
• W2895872185 creator A5053447036 @default.
• W2895872185 creator A5071011065 @default.
• W2895872185 creator A5082946065 @default.
• W2895872185 date "2018-11-01" @default.
• W2895872185 modified "2023-09-26" @default.
• W2895872185 title "Aging Alters the Relative Contributions of the Sympathetic and Parasympathetic Nervous System to Blood Pressure Control in Women" @default.
• W2895872185 cites W1537095310 @default.
• W2895872185 cites W1604168055 @default.
• W2895872185 cites W1661846981 @default.
• W2895872185 cites W1702568920 @default.
• W2895872185 cites W1996473042 @default.
• W2895872185 cites W2017492990 @default.
• W2895872185 cites W2050286226 @default.
• W2895872185 cites W2055289824 @default.
• W2895872185 cites W2057834349 @default.
• W2895872185 cites W2091333777 @default.
• W2895872185 cites W2094217880 @default.
• W2895872185 cites W2095233676 @default.
• W2895872185 cites W2099986378 @default.
• W2895872185 cites W2117017490 @default.
• W2895872185 cites W2122464624 @default.
• W2895872185 cites W2136115725 @default.
• W2895872185 cites W2139729561 @default.
• W2895872185 cites W2157526886 @default.
• W2895872185 cites W2172188123 @default.
• W2895872185 cites W2181663293 @default.
• W2895872185 cites W2327802709 @default.
• W2895872185 cites W2336020467 @default.
• W2895872185 cites W2759190050 @default.
• W2895872185 cites W2768780148 @default.
• W2895872185 cites W2891696964 @default.
• W2895872185 cites W4298441315 @default.
• W2895872185 doi "https://doi.org/10.1161/hypertensionaha.118.11550" @default.
• W2895872185 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6211807" @default.
• W2895872185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30354803" @default.
• W2895872185 hasPublicationYear "2018" @default.
• W2895872185 type Work @default.
• W2895872185 sameAs 2895872185 @default.
• W2895872185 citedByCount "37" @default.
• W2895872185 countsByYear W28958721852019 @default.
• W2895872185 countsByYear W28958721852020 @default.
• W2895872185 countsByYear W28958721852021 @default.
• W2895872185 countsByYear W28958721852022 @default.
• W2895872185 countsByYear W28958721852023 @default.
• W2895872185 crossrefType "journal-article" @default.
• W2895872185 hasAuthorship W2895872185A5003362911 @default.
• W2895872185 hasAuthorship W2895872185A5029721543 @default.
• W2895872185 hasAuthorship W2895872185A5031480179 @default.
• W2895872185 hasAuthorship W2895872185A5053447036 @default.
• W2895872185 hasAuthorship W2895872185A5071011065 @default.
• W2895872185 hasAuthorship W2895872185A5082946065 @default.
• W2895872185 hasBestOaLocation W28958721851 @default.
• W2895872185 hasConcept C126322002 @default.
• W2895872185 hasConcept C134018914 @default.
• W2895872185 hasConcept C170493617 @default.
• W2895872185 hasConcept C191237925 @default.
• W2895872185 hasConcept C2775893369 @default.
• W2895872185 hasConcept C2775898464 @default.
• W2895872185 hasConcept C2775910092 @default.
• W2895872185 hasConcept C2776533406 @default.
• W2895872185 hasConcept C2777372248 @default.
• W2895872185 hasConcept C2777952989 @default.
• W2895872185 hasConcept C2777953023 @default.
• W2895872185 hasConcept C2778024521 @default.
• W2895872185 hasConcept C2778468042 @default.
• W2895872185 hasConcept C2779306644 @default.
• W2895872185 hasConcept C42219234 @default.
• W2895872185 hasConcept C71924100 @default.
• W2895872185 hasConcept C84393581 @default.
• W2895872185 hasConceptScore W2895872185C126322002 @default.
• W2895872185 hasConceptScore W2895872185C134018914 @default.
• W2895872185 hasConceptScore W2895872185C170493617 @default.
• W2895872185 hasConceptScore W2895872185C191237925 @default.
• W2895872185 hasConceptScore W2895872185C2775893369 @default.
• W2895872185 hasConceptScore W2895872185C2775898464 @default.
• W2895872185 hasConceptScore W2895872185C2775910092 @default.
• W2895872185 hasConceptScore W2895872185C2776533406 @default.
• W2895872185 hasConceptScore W2895872185C2777372248 @default.
• W2895872185 hasConceptScore W2895872185C2777952989 @default.
• W2895872185 hasConceptScore W2895872185C2777953023 @default.
• W2895872185 hasConceptScore W2895872185C2778024521 @default.
• W2895872185 hasConceptScore W2895872185C2778468042 @default.
• W2895872185 hasConceptScore W2895872185C2779306644 @default.
• W2895872185 hasConceptScore W2895872185C42219234 @default.
• W2895872185 hasConceptScore W2895872185C71924100 @default.
• W2895872185 hasConceptScore W2895872185C84393581 @default.
• W2895872185 hasIssue "5" @default.
• W2895872185 hasLocation W28958721851 @default.
• W2895872185 hasLocation W28958721852 @default.
• W2895872185 hasLocation W28958721853 @default.
• W2895872185 hasLocation W28958721854 @default.
• W2895872185 hasOpenAccess W2895872185 @default.
• W2895872185 hasPrimaryLocation W28958721851 @default.

• next