FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895875344> ?p ?o ?g. }

• W2895875344 abstract "The neocortex generates at the dorsal region of the pallium in the forebrain. Several adjacent structures also contribute with neurons to neocortex. Ventral pallium is considered to generate several populations of neurons that arrive through tangential migration to the neocortex. Amongst them are the Cajal-Retzius cells and some transient pyramidal neurons. However, the specific site and timing of generation, trajectory of migration and actual contribution to the pyramidal population remains elusive. Here we investigate the spatio-temporal origin of neuronal populations from ventral pallium in an in vivo model, using a transposase mediated in utero electroporation method in embryonic mouse in vivo. From E11 to E14 cells born at the lateral corner of the neocortical neuroepithelium including the ventral pallium migrated ventro-laterally to settle all areas of the ventral telencephalon. Specifically, neurons migrated into amygdala, olfactory cortices and claustrum. However, we found no evidence for any neurons migrating tangentially towards the neocortex, regardless the antero-posterior level and developmental time of the electroporation. Our results challenge the described ventral-pallial origin of the transient pyramidal neuron population. In order to find the exact origin of cortical neurons that were previously Dbx1-fate mapped we used the promoter region of the murine Dbx1 locus to selectively target Dbx1-expressing progenitors and label their lineage. We found these progenitors in low numbers in all pallial areas, and not only in the ventral pallial ventricular zone. Our findings on the local cortical origin of the Dbx1-expressing pyramidal neurons reconcile the observation of Dbx1 expressing neurons in the cortex without evidence of dorsal tangential migration from ventral pallium and provide a new framework for the origin of the transient Dbx1-derived pyramidal neuron population. We conclude that these neurons are born locally within the dorsal pallial neuroepithelium." @default.
• W2895875344 created "2018-10-26" @default.
• W2895875344 creator A5003946825 @default.
• W2895875344 creator A5010319571 @default.
• W2895875344 creator A5013908994 @default.
• W2895875344 creator A5060963085 @default.
• W2895875344 creator A5084442891 @default.
• W2895875344 date "2018-10-31" @default.
• W2895875344 modified "2023-10-15" @default.
• W2895875344 title "Dbx1-Derived Pyramidal Neurons Are Generated Locally in the Developing Murine Neocortex" @default.
• W2895875344 cites W1912820128 @default.
• W2895875344 cites W1979832807 @default.
• W2895875344 cites W1981045324 @default.
• W2895875344 cites W1985785093 @default.
• W2895875344 cites W1994924452 @default.
• W2895875344 cites W1999077862 @default.
• W2895875344 cites W1999147940 @default.
• W2895875344 cites W2036485506 @default.
• W2895875344 cites W2042810734 @default.
• W2895875344 cites W2045618671 @default.
• W2895875344 cites W2060316084 @default.
• W2895875344 cites W2067551890 @default.
• W2895875344 cites W2078284356 @default.
• W2895875344 cites W2080417264 @default.
• W2895875344 cites W2105967476 @default.
• W2895875344 cites W2110513111 @default.
• W2895875344 cites W2110572115 @default.
• W2895875344 cites W2125789251 @default.
• W2895875344 cites W2139043811 @default.
• W2895875344 cites W2149683541 @default.
• W2895875344 cites W2150692263 @default.
• W2895875344 cites W2208949087 @default.
• W2895875344 cites W2211303435 @default.
• W2895875344 cites W2410678727 @default.
• W2895875344 cites W2765854052 @default.
• W2895875344 cites W2782031780 @default.
• W2895875344 doi "https://doi.org/10.3389/fnins.2018.00792" @default.
• W2895875344 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6220037" @default.
• W2895875344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30429769" @default.
• W2895875344 hasPublicationYear "2018" @default.
• W2895875344 type Work @default.
• W2895875344 sameAs 2895875344 @default.
• W2895875344 citedByCount "9" @default.
• W2895875344 countsByYear W28958753442019 @default.
• W2895875344 countsByYear W28958753442020 @default.
• W2895875344 countsByYear W28958753442021 @default.
• W2895875344 countsByYear W28958753442023 @default.
• W2895875344 crossrefType "journal-article" @default.
• W2895875344 hasAuthorship W2895875344A5003946825 @default.
• W2895875344 hasAuthorship W2895875344A5010319571 @default.
• W2895875344 hasAuthorship W2895875344A5013908994 @default.
• W2895875344 hasAuthorship W2895875344A5060963085 @default.
• W2895875344 hasAuthorship W2895875344A5084442891 @default.
• W2895875344 hasBestOaLocation W28958753441 @default.
• W2895875344 hasConcept C104317684 @default.
• W2895875344 hasConcept C105702510 @default.
• W2895875344 hasConcept C144024400 @default.
• W2895875344 hasConcept C149923435 @default.
• W2895875344 hasConcept C169760540 @default.
• W2895875344 hasConcept C186852380 @default.
• W2895875344 hasConcept C201750760 @default.
• W2895875344 hasConcept C2777222312 @default.
• W2895875344 hasConcept C2780597806 @default.
• W2895875344 hasConcept C2781041448 @default.
• W2895875344 hasConcept C28328180 @default.
• W2895875344 hasConcept C2908647359 @default.
• W2895875344 hasConcept C50738837 @default.
• W2895875344 hasConcept C529278444 @default.
• W2895875344 hasConcept C533869091 @default.
• W2895875344 hasConcept C55493867 @default.
• W2895875344 hasConcept C63101894 @default.
• W2895875344 hasConcept C86803240 @default.
• W2895875344 hasConcept C95444343 @default.
• W2895875344 hasConceptScore W2895875344C104317684 @default.
• W2895875344 hasConceptScore W2895875344C105702510 @default.
• W2895875344 hasConceptScore W2895875344C144024400 @default.
• W2895875344 hasConceptScore W2895875344C149923435 @default.
• W2895875344 hasConceptScore W2895875344C169760540 @default.
• W2895875344 hasConceptScore W2895875344C186852380 @default.
• W2895875344 hasConceptScore W2895875344C201750760 @default.
• W2895875344 hasConceptScore W2895875344C2777222312 @default.
• W2895875344 hasConceptScore W2895875344C2780597806 @default.
• W2895875344 hasConceptScore W2895875344C2781041448 @default.
• W2895875344 hasConceptScore W2895875344C28328180 @default.
• W2895875344 hasConceptScore W2895875344C2908647359 @default.
• W2895875344 hasConceptScore W2895875344C50738837 @default.
• W2895875344 hasConceptScore W2895875344C529278444 @default.
• W2895875344 hasConceptScore W2895875344C533869091 @default.
• W2895875344 hasConceptScore W2895875344C55493867 @default.
• W2895875344 hasConceptScore W2895875344C63101894 @default.
• W2895875344 hasConceptScore W2895875344C86803240 @default.
• W2895875344 hasConceptScore W2895875344C95444343 @default.
• W2895875344 hasFunder F4320307846 @default.
• W2895875344 hasLocation W28958753441 @default.
• W2895875344 hasLocation W28958753442 @default.
• W2895875344 hasLocation W28958753443 @default.
• W2895875344 hasLocation W28958753444 @default.
• W2895875344 hasLocation W28958753445 @default.
• W2895875344 hasLocation W28958753446 @default.
• W2895875344 hasOpenAccess W2895875344 @default.

• next