FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895880339> ?p ?o ?g. }

• W2895880339 abstract "Adenocarcinomas and active granulomas can both have a spiculated appearance on computed tomography (CT) and both are often fluorodeoxyglucose (FDG) avid on positron emission tomography (PET) scan, making them difficult to distinguish. Consequently, patients with benign granulomas are often subjected to invasive surgical biopsies or resections. In this study, quantitative vessel tortuosity (QVT), a novel CT imaging biomarker to distinguish between benign granulomas and adenocarcinomas on routine non-contrast lung CT scans is introduced. Our study comprised of CT scans of 290 patients from two different institutions, one cohort for training (N = 145) and the other (N = 145) for independent validation. In conjunction with a machine learning classifier, the top informative and stable QVT features yielded an area under receiver operating characteristic curve (ROC AUC) of 0.85 in the independent validation set. On the same cohort, the corresponding AUCs for two human experts including a radiologist and a pulmonologist were found to be 0.61 and 0.60, respectively. QVT features also outperformed well known shape and textural radiomic features which had a maximum AUC of 0.73 (p-value = 0.002), as well as features learned using a convolutional neural network AUC = 0.76 (p-value = 0.028). Our results suggest that QVT features could potentially serve as a non-invasive imaging biomarker to distinguish granulomas from adenocarcinomas on non-contrast CT scans." @default.
• W2895880339 created "2018-10-26" @default.
• W2895880339 creator A5022833468 @default.
• W2895880339 creator A5027642699 @default.
• W2895880339 creator A5036343196 @default.
• W2895880339 creator A5043328589 @default.
• W2895880339 creator A5047759484 @default.
• W2895880339 creator A5047904907 @default.
• W2895880339 creator A5065367784 @default.
• W2895880339 creator A5066861614 @default.
• W2895880339 creator A5079122373 @default.
• W2895880339 creator A5080439167 @default.
• W2895880339 creator A5088424146 @default.
• W2895880339 creator A5091618934 @default.
• W2895880339 creator A5091872663 @default.
• W2895880339 date "2018-10-16" @default.
• W2895880339 modified "2023-10-14" @default.
• W2895880339 title "Quantitative vessel tortuosity: A potential CT imaging biomarker for distinguishing lung granulomas from adenocarcinomas" @default.
• W2895880339 cites W1565276921 @default.
• W2895880339 cites W1596717185 @default.
• W2895880339 cites W1606467544 @default.
• W2895880339 cites W1639104204 @default.
• W2895880339 cites W1966847100 @default.
• W2895880339 cites W1972526834 @default.
• W2895880339 cites W1981045255 @default.
• W2895880339 cites W1990994043 @default.
• W2895880339 cites W1991755688 @default.
• W2895880339 cites W1997030078 @default.
• W2895880339 cites W2005992530 @default.
• W2895880339 cites W2008428440 @default.
• W2895880339 cites W2009911194 @default.
• W2895880339 cites W2026616100 @default.
• W2895880339 cites W2035602559 @default.
• W2895880339 cites W2036382630 @default.
• W2895880339 cites W2038148250 @default.
• W2895880339 cites W2045690769 @default.
• W2895880339 cites W2046605403 @default.
• W2895880339 cites W2048497584 @default.
• W2895880339 cites W2054113582 @default.
• W2895880339 cites W2059432853 @default.
• W2895880339 cites W2060766460 @default.
• W2895880339 cites W2061077502 @default.
• W2895880339 cites W2096579040 @default.
• W2895880339 cites W2103004421 @default.
• W2895880339 cites W2110290656 @default.
• W2895880339 cites W2114175038 @default.
• W2895880339 cites W2114281628 @default.
• W2895880339 cites W2122111042 @default.
• W2895880339 cites W2124735791 @default.
• W2895880339 cites W2128739912 @default.
• W2895880339 cites W2140775860 @default.
• W2895880339 cites W2151570219 @default.
• W2895880339 cites W2154053567 @default.
• W2895880339 cites W2154823510 @default.
• W2895880339 cites W2155893237 @default.
• W2895880339 cites W2158548004 @default.
• W2895880339 cites W2164711090 @default.
• W2895880339 cites W2169296882 @default.
• W2895880339 cites W2174661749 @default.
• W2895880339 cites W2186541611 @default.
• W2895880339 cites W2255066369 @default.
• W2895880339 cites W2322371438 @default.
• W2895880339 cites W2383601426 @default.
• W2895880339 cites W2470491115 @default.
• W2895880339 cites W2523726602 @default.
• W2895880339 cites W2524947832 @default.
• W2895880339 cites W2582043099 @default.
• W2895880339 cites W2584017349 @default.
• W2895880339 cites W2596686700 @default.
• W2895880339 cites W2604796850 @default.
• W2895880339 cites W2753464331 @default.
• W2895880339 cites W2762636605 @default.
• W2895880339 cites W2767346095 @default.
• W2895880339 cites W2919115771 @default.
• W2895880339 cites W4240558230 @default.
• W2895880339 cites W4248973632 @default.
• W2895880339 cites W948663339 @default.
• W2895880339 doi "https://doi.org/10.1038/s41598-018-33473-0" @default.
• W2895880339 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6191462" @default.
• W2895880339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30327507" @default.
• W2895880339 hasPublicationYear "2018" @default.
• W2895880339 type Work @default.
• W2895880339 sameAs 2895880339 @default.
• W2895880339 citedByCount "23" @default.
• W2895880339 countsByYear W28958803392019 @default.
• W2895880339 countsByYear W28958803392020 @default.
• W2895880339 countsByYear W28958803392021 @default.
• W2895880339 countsByYear W28958803392022 @default.
• W2895880339 countsByYear W28958803392023 @default.
• W2895880339 crossrefType "journal-article" @default.
• W2895880339 hasAuthorship W2895880339A5022833468 @default.
• W2895880339 hasAuthorship W2895880339A5027642699 @default.
• W2895880339 hasAuthorship W2895880339A5036343196 @default.
• W2895880339 hasAuthorship W2895880339A5043328589 @default.
• W2895880339 hasAuthorship W2895880339A5047759484 @default.
• W2895880339 hasAuthorship W2895880339A5047904907 @default.
• W2895880339 hasAuthorship W2895880339A5065367784 @default.
• W2895880339 hasAuthorship W2895880339A5066861614 @default.
• W2895880339 hasAuthorship W2895880339A5079122373 @default.
• W2895880339 hasAuthorship W2895880339A5080439167 @default.

• next