FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895897802> ?p ?o ?g. }

• W2895897802 endingPage "8" @default.
• W2895897802 startingPage "1" @default.
• W2895897802 abstract "N-acetylcysteine, a sulphur-containing amino acid for the treatment of paracetamol overdose and chronic obstructive pulmonary disease, is a widely available off-the-shelf oral antioxidant supplement in many countries. With the potential to modulate several neurological pathways, including glutamate dysregulation, oxidative stress, and inflammation that can be beneficial to the brain functions, N-acetylcysteine is being explored as an adjunctive therapy for many psychiatric conditions. This narrative review synthesises and presents the current evidence from systematic reviews, meta-analyses, and latest clinical trials on N-acetylcysteine for addiction and substance abuse, schizophrenia, obsessive-compulsive and related disorders, and mood disorders. Good evidence exists to support the use of N-acetylcysteine as an adjunct treatment to reduce the total and negative symptoms of schizophrenia. N-acetylcysteine also appears to be effective in reducing craving in substance use disorders, especially for the treatment of cocaine and cannabis use among young people, in addition to preventing relapse in already abstinent individuals. Effects of N-acetylcysteine on obsessive-compulsive and related disorders, as well as on mood disorders, remain unclear with mixed reviews, even though promising evidence does exist. Larger and better-designed studies are required to further investigate the clinical effectiveness of N-acetylcysteine in these areas. Oral N-acetylcysteine is safe and well tolerated without any considerable adverse effects. Current evidence supports its use as an adjunctive therapy clinically for psychiatric conditions, administered concomitantly with existing medications, with a recommended dosage between 2000 and 2400 mg/day." @default.
• W2895897802 created "2018-10-26" @default.
• W2895897802 creator A5007077726 @default.
• W2895897802 creator A5045017851 @default.
• W2895897802 creator A5070500568 @default.
• W2895897802 date "2018-10-22" @default.
• W2895897802 modified "2023-10-14" @default.
• W2895897802 title "N-Acetylcysteine for the Treatment of Psychiatric Disorders: A Review of Current Evidence" @default.
• W2895897802 cites W111768372 @default.
• W2895897802 cites W1771465408 @default.
• W2895897802 cites W1921153043 @default.
• W2895897802 cites W1951949051 @default.
• W2895897802 cites W1959849744 @default.
• W2895897802 cites W1963479676 @default.
• W2895897802 cites W1970774237 @default.
• W2895897802 cites W1971398808 @default.
• W2895897802 cites W1981486198 @default.
• W2895897802 cites W1983954953 @default.
• W2895897802 cites W1992261726 @default.
• W2895897802 cites W1996517171 @default.
• W2895897802 cites W2005904867 @default.
• W2895897802 cites W2017032137 @default.
• W2895897802 cites W2032453542 @default.
• W2895897802 cites W2035477056 @default.
• W2895897802 cites W2042120820 @default.
• W2895897802 cites W2058078376 @default.
• W2895897802 cites W2059140543 @default.
• W2895897802 cites W2059975564 @default.
• W2895897802 cites W2088125572 @default.
• W2895897802 cites W2095670320 @default.
• W2895897802 cites W2099204286 @default.
• W2895897802 cites W2099839877 @default.
• W2895897802 cites W2102796622 @default.
• W2895897802 cites W2104962197 @default.
• W2895897802 cites W2105920925 @default.
• W2895897802 cites W2119504117 @default.
• W2895897802 cites W2120532948 @default.
• W2895897802 cites W2124107177 @default.
• W2895897802 cites W2131324637 @default.
• W2895897802 cites W2167884432 @default.
• W2895897802 cites W2290282548 @default.
• W2895897802 cites W2343957148 @default.
• W2895897802 cites W240506283 @default.
• W2895897802 cites W2412363222 @default.
• W2895897802 cites W2439394256 @default.
• W2895897802 cites W2512649231 @default.
• W2895897802 cites W2520829703 @default.
• W2895897802 cites W2536443623 @default.
• W2895897802 cites W2586384568 @default.
• W2895897802 cites W2587689107 @default.
• W2895897802 cites W2592198919 @default.
• W2895897802 cites W2603299926 @default.
• W2895897802 cites W2616167123 @default.
• W2895897802 cites W2624100118 @default.
• W2895897802 cites W2624234496 @default.
• W2895897802 cites W2756375477 @default.
• W2895897802 cites W2793719699 @default.
• W2895897802 cites W2999118676 @default.
• W2895897802 doi "https://doi.org/10.1155/2018/2469486" @default.
• W2895897802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6217900" @default.
• W2895897802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30426004" @default.
• W2895897802 hasPublicationYear "2018" @default.
• W2895897802 type Work @default.
• W2895897802 sameAs 2895897802 @default.
• W2895897802 citedByCount "56" @default.
• W2895897802 countsByYear W28958978022018 @default.
• W2895897802 countsByYear W28958978022019 @default.
• W2895897802 countsByYear W28958978022020 @default.
• W2895897802 countsByYear W28958978022021 @default.
• W2895897802 countsByYear W28958978022022 @default.
• W2895897802 countsByYear W28958978022023 @default.
• W2895897802 crossrefType "journal-article" @default.
• W2895897802 hasAuthorship W2895897802A5007077726 @default.
• W2895897802 hasAuthorship W2895897802A5045017851 @default.
• W2895897802 hasAuthorship W2895897802A5070500568 @default.
• W2895897802 hasBestOaLocation W28958978021 @default.
• W2895897802 hasConcept C118552586 @default.
• W2895897802 hasConcept C126322002 @default.
• W2895897802 hasConcept C185592680 @default.
• W2895897802 hasConcept C197934379 @default.
• W2895897802 hasConcept C205778803 @default.
• W2895897802 hasConcept C2776412080 @default.
• W2895897802 hasConcept C2777134132 @default.
• W2895897802 hasConcept C2777847592 @default.
• W2895897802 hasConcept C2778004101 @default.
• W2895897802 hasConcept C2780733359 @default.
• W2895897802 hasConcept C3018162438 @default.
• W2895897802 hasConcept C535046627 @default.
• W2895897802 hasConcept C55493867 @default.
• W2895897802 hasConcept C558461103 @default.
• W2895897802 hasConcept C71924100 @default.
• W2895897802 hasConcept C98274493 @default.
• W2895897802 hasConceptScore W2895897802C118552586 @default.
• W2895897802 hasConceptScore W2895897802C126322002 @default.
• W2895897802 hasConceptScore W2895897802C185592680 @default.
• W2895897802 hasConceptScore W2895897802C197934379 @default.
• W2895897802 hasConceptScore W2895897802C205778803 @default.
• W2895897802 hasConceptScore W2895897802C2776412080 @default.

• next