Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895916637> ?p ?o ?g. }
- W2895916637 abstract "Abstract Hemostasis is a critical homeostatic mechanism of survival that involves vascular, cellular, and plasma components that interact to stop bleeding. Vascular effects include vasoconstriction, expression of procoagulant factors such as tissue factor, and loss of normal anticoagulant functions of the endothelium. Coagulation and clot formation occur by cellular and humoral factors that interact together with local and systemic factors. Surgery produces complex alterations and defects in hemostatic mechanisms, particularly in trauma, cardiac surgery with or without cardiopulmonary bypass, major orthopedic surgery, and neurosurgery. In many patients, multiple quantitative and qualitative hemostatic abnormalities develop as part of surgery, tissue injury, and complex underlying medical conditions. Additionally, the increasing use of multiple anticoagulation agents to treat cardiovascular disease contributes to preexisting perioperative hemostatic defects and increases the potential for bleeding. Furthermore, massive bleeding can produce an acquired hemostatic defect called massive transfusion coagulopathy that is characterized by tissue injury, dilutional hemostatic changes, hypothermia, acidosis, and multiorgan dysfunction." @default.
- W2895916637 created "2018-10-26" @default.
- W2895916637 creator A5008083283 @default.
- W2895916637 creator A5053864173 @default.
- W2895916637 creator A5086401839 @default.
- W2895916637 date "2019-01-01" @default.
- W2895916637 modified "2023-10-16" @default.
- W2895916637 title "Blood and Coagulation" @default.
- W2895916637 cites W115624719 @default.
- W2895916637 cites W117940715 @default.
- W2895916637 cites W14480909 @default.
- W2895916637 cites W1531281563 @default.
- W2895916637 cites W1534077777 @default.
- W2895916637 cites W1948915477 @default.
- W2895916637 cites W1965708535 @default.
- W2895916637 cites W1968925132 @default.
- W2895916637 cites W1971426640 @default.
- W2895916637 cites W1973574476 @default.
- W2895916637 cites W1976260077 @default.
- W2895916637 cites W1981264072 @default.
- W2895916637 cites W1984396324 @default.
- W2895916637 cites W1985198125 @default.
- W2895916637 cites W1991737358 @default.
- W2895916637 cites W1996249129 @default.
- W2895916637 cites W2002461262 @default.
- W2895916637 cites W2003513950 @default.
- W2895916637 cites W2003895206 @default.
- W2895916637 cites W2005401250 @default.
- W2895916637 cites W2007945858 @default.
- W2895916637 cites W2008819521 @default.
- W2895916637 cites W2011740324 @default.
- W2895916637 cites W2013155340 @default.
- W2895916637 cites W2014720138 @default.
- W2895916637 cites W2018129107 @default.
- W2895916637 cites W2020706581 @default.
- W2895916637 cites W2025778465 @default.
- W2895916637 cites W2027093124 @default.
- W2895916637 cites W2029922639 @default.
- W2895916637 cites W2030695838 @default.
- W2895916637 cites W2031018845 @default.
- W2895916637 cites W2044211202 @default.
- W2895916637 cites W2049222615 @default.
- W2895916637 cites W2054330426 @default.
- W2895916637 cites W2058157135 @default.
- W2895916637 cites W2060972622 @default.
- W2895916637 cites W2062212660 @default.
- W2895916637 cites W2083005745 @default.
- W2895916637 cites W2085356598 @default.
- W2895916637 cites W2086609126 @default.
- W2895916637 cites W2100989562 @default.
- W2895916637 cites W2101241318 @default.
- W2895916637 cites W2106213640 @default.
- W2895916637 cites W2109973294 @default.
- W2895916637 cites W2112564023 @default.
- W2895916637 cites W2112719737 @default.
- W2895916637 cites W2115509671 @default.
- W2895916637 cites W2123622204 @default.
- W2895916637 cites W2124432833 @default.
- W2895916637 cites W2126091538 @default.
- W2895916637 cites W2127414127 @default.
- W2895916637 cites W2127666633 @default.
- W2895916637 cites W2129515316 @default.
- W2895916637 cites W2131885056 @default.
- W2895916637 cites W2133463223 @default.
- W2895916637 cites W2133594900 @default.
- W2895916637 cites W2135335158 @default.
- W2895916637 cites W2140436541 @default.
- W2895916637 cites W2145834923 @default.
- W2895916637 cites W2149792950 @default.
- W2895916637 cites W2150986083 @default.
- W2895916637 cites W2152877944 @default.
- W2895916637 cites W2157876594 @default.
- W2895916637 cites W2161800214 @default.
- W2895916637 cites W2162088713 @default.
- W2895916637 cites W2213178491 @default.
- W2895916637 cites W2338438098 @default.
- W2895916637 cites W2475108114 @default.
- W2895916637 cites W2560554479 @default.
- W2895916637 cites W2608188783 @default.
- W2895916637 cites W2767375178 @default.
- W2895916637 cites W2773335600 @default.
- W2895916637 cites W2773568954 @default.
- W2895916637 cites W2781213254 @default.
- W2895916637 cites W2912349604 @default.
- W2895916637 cites W2913967451 @default.
- W2895916637 cites W29311527 @default.
- W2895916637 cites W3021235715 @default.
- W2895916637 cites W305499418 @default.
- W2895916637 cites W3093693179 @default.
- W2895916637 cites W3155174407 @default.
- W2895916637 cites W3183915260 @default.
- W2895916637 cites W79694754 @default.
- W2895916637 cites W2000950265 @default.
- W2895916637 cites W2064778793 @default.
- W2895916637 cites W2066501971 @default.
- W2895916637 cites W2083277617 @default.
- W2895916637 cites W2084186985 @default.
- W2895916637 cites W2124120026 @default.
- W2895916637 cites W2416867069 @default.
- W2895916637 doi "https://doi.org/10.1016/b978-0-323-48110-6.00043-0" @default.