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• W2895930782 abstract "Androgen deprivation therapy (ADT) is commonly used to treat prostate cancer. However, side effects of ADT often lead to reduced quality of life and physical function. Existing evidence demonstrates that exercise can ameliorate multiple treatment-related side effects for men on ADT, yet adherence rates are often low. The method of exercise delivery (e.g., supervised group in-centre vs. individual home-based) may be important from clinical and economic perspectives; however, few studies have compared different delivery models. Additionally, long-term exercise adherence and an understanding of predictors of adherence are critical to achieving sustained benefits, but such data are lacking. The primary aim of this multi-centre phase III non-inferiority randomized controlled trial is to determine whether a home-based delivery model is non-inferior to a group-based delivery model in terms of benefits in fatigue and fitness in this population. Two other key aims include examining cost-effectiveness and long-term adherence.Men diagnosed with prostate cancer of any stage, starting or continuing on ADT for at least 6 months, fluent in English, and living close to a study centre are eligible. Participants complete five assessments over 12 months (baseline and every 3 months during the 6-month intervention and 6-month follow-up phases), including a fitness assessment and self-report questionnaires. Biological outcomes are collected at baseline, 6, and 12 months. A total of 200 participants will be randomized in a 1:1 fashion to supervised group training or home-based training supported by smartphones, health coaches, and Fitbit technology. Participants are asked to complete 4 to 5 exercise sessions per week, incorporating aerobic, resistance and flexibility training. Outcomes include fatigue, quality of life, fitness measures, body composition, biological outcomes, and program adherence. Cost information will be obtained using patient diary-based self-report and utilities via the EQ-5D.To disseminate publicly funded exercise programs widely, clinical efficacy and cost-effectiveness have to be demonstrated. The goals of this trial are to provide these data along with an increased understanding of adherence to exercise among men with prostate cancer receiving ADT.The trial has been registered at clinicaltrials.gov (Registration # NCT02834416 ). Registration date was June 2, 2016." @default.
• W2895930782 created "2018-10-26" @default.
• W2895930782 creator A5001659044 @default.
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• W2895930782 date "2018-10-23" @default.
• W2895930782 modified "2023-09-29" @default.
• W2895930782 title "Protocol for a phase III RCT and economic analysis of two exercise delivery methods in men with PC on ADT" @default.
• W2895930782 cites W103295186 @default.
• W2895930782 cites W120137781 @default.
• W2895930782 cites W12860375 @default.
• W2895930782 cites W1502415307 @default.
• W2895930782 cites W1540983776 @default.
• W2895930782 cites W1566841485 @default.
• W2895930782 cites W1586793705 @default.
• W2895930782 cites W1587319193 @default.
• W2895930782 cites W175660244 @default.
• W2895930782 cites W1814793649 @default.
• W2895930782 cites W1837868585 @default.
• W2895930782 cites W1968590281 @default.
• W2895930782 cites W1969259971 @default.
• W2895930782 cites W1969298178 @default.
• W2895930782 cites W1969735359 @default.
• W2895930782 cites W1969930854 @default.
• W2895930782 cites W1970657768 @default.
• W2895930782 cites W1971653725 @default.
• W2895930782 cites W1974682148 @default.
• W2895930782 cites W1975071629 @default.
• W2895930782 cites W1976004349 @default.
• W2895930782 cites W1977652660 @default.
• W2895930782 cites W1979447730 @default.
• W2895930782 cites W1980832849 @default.
• W2895930782 cites W1982876385 @default.
• W2895930782 cites W1983620214 @default.
• W2895930782 cites W1987003762 @default.
• W2895930782 cites W1987109043 @default.
• W2895930782 cites W1988223280 @default.
• W2895930782 cites W1990166011 @default.
• W2895930782 cites W1990869186 @default.
• W2895930782 cites W1994044267 @default.
• W2895930782 cites W1997336301 @default.
• W2895930782 cites W1997732940 @default.
• W2895930782 cites W2000696254 @default.
• W2895930782 cites W2002948491 @default.
• W2895930782 cites W2003340521 @default.
• W2895930782 cites W2004008756 @default.
• W2895930782 cites W2004909463 @default.
• W2895930782 cites W2005671531 @default.
• W2895930782 cites W2006286039 @default.
• W2895930782 cites W2006655881 @default.
• W2895930782 cites W2008374436 @default.
• W2895930782 cites W2008795349 @default.
• W2895930782 cites W2010528776 @default.
• W2895930782 cites W2011781303 @default.
• W2895930782 cites W2013136992 @default.
• W2895930782 cites W2013232728 @default.
• W2895930782 cites W2014011665 @default.
• W2895930782 cites W2014751124 @default.
• W2895930782 cites W2014892421 @default.
• W2895930782 cites W2016972400 @default.
• W2895930782 cites W2017916933 @default.
• W2895930782 cites W2019136566 @default.
• W2895930782 cites W2019894412 @default.
• W2895930782 cites W2024216767 @default.
• W2895930782 cites W2025283489 @default.
• W2895930782 cites W2025958195 @default.
• W2895930782 cites W2031762038 @default.
• W2895930782 cites W2033380798 @default.
• W2895930782 cites W2036291769 @default.
• W2895930782 cites W2036564302 @default.
• W2895930782 cites W2038962823 @default.
• W2895930782 cites W2039035512 @default.
• W2895930782 cites W2047678698 @default.
• W2895930782 cites W2047915454 @default.
• W2895930782 cites W2049458773 @default.
• W2895930782 cites W2051963354 @default.
• W2895930782 cites W2052783921 @default.
• W2895930782 cites W2053446715 @default.
• W2895930782 cites W2054052990 @default.
• W2895930782 cites W2055308459 @default.
• W2895930782 cites W2056592226 @default.
• W2895930782 cites W2056693498 @default.
• W2895930782 cites W2057438210 @default.
• W2895930782 cites W2057830194 @default.
• W2895930782 cites W2061744871 @default.
• W2895930782 cites W2062075603 @default.
• W2895930782 cites W2062352318 @default.
• W2895930782 cites W2064142663 @default.
• W2895930782 cites W2064860072 @default.
• W2895930782 cites W2065008784 @default.
• W2895930782 cites W2066899660 @default.

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