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- W2895941696 abstract "Ultrasonic ‘phased tracking method’ (PTM) enables non-invasive measurements of pulse wave velocity (PWV). We aim to investigate PWV and pulse pressure (PP) in growth-restricted fetuses with or without demonstrated flow signals in right distal coronary artery (dRCA). We analyzed 46 growth-restricted fetuses on 20-35 weeks. Demonstration of dRCA was defined when diastolic dominant flow velocity was proven in pulsed Doppler FFT waveform. Fetal descending aorta was identified in long axis direction using conventional B-mode with a convex array probe (5-6MHz). Row radiofrequency signals were recorded from the vessel wall of descending aorta. Off-line analysis was attempted for wall motion velocity wave in at least 5 cardiac cycles. We employed PTM for measurement of PWV. Pulse pressure (PP) was estimated from PWV and maximum flow velocity in descending aorta using formula of Water-hammer. We could demonstrate dRCA flow in 16 cases and not in 30. Increased PWVs were shown in dRCA demonstrated cases (5.0+/-0.34 versus 3.0+/-0.12 (mean+/-SE) [m/s], P<0.01 in two-way ANOVA). We could also prove elevated PPs in demonstrated cases (3.6 +/- 0.23 versus 2.7 +/- 0.18 [kPa], P<0.01) (figure). Measurement of fetal PWV using PTM is feasible non-invasive approach to evaluate fetal hemodynamics and enable us detailed analysis of myocardial blood flow re-distribution (heart-sparing effect) in growth-restricted fetuses. Increased PWV and PP in cases with demonstrated dRCA flow signals suggested elevated diastolic pressure and pulse pressure in them. Supporting information can be found in the online version of this abstract Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2895941696 created "2018-10-26" @default.
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- W2895941696 date "2018-10-01" @default.
- W2895941696 modified "2023-10-14" @default.
- W2895941696 title "P04.11: Increased fetal pulse wave velocity and pulse pressure in growth-restricted fetuses with heart-sparing effect" @default.
- W2895941696 doi "https://doi.org/10.1002/uog.19654" @default.
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