Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895948975> ?p ?o ?g. }
- W2895948975 endingPage "87" @default.
- W2895948975 startingPage "77" @default.
- W2895948975 abstract "Abstract Vitamin K1 has recently been identified as a potentially important nutrient for prevention of chronic diseases, especially those associated with aging, like osteoporosis and cardiovascular disease. Currently the majority of Vitamin K1 is produced via chemical synthesis; the aim of this work is to examine the potential to produce Vitamin K1 using microalgae. Biological synthesis produces only the active E-isomer, whereas chemical synthesis produces 10–20% of the inactive Z-isomer. Biosynthesis also utilises mild operating conditions, sustainable production methods, and has the potential to simultaneously produce other beneficial compounds. Seven different species of microalgae were screened; the cyanobacterium Anabaena cylindrica was identified as the richest source of vitamin K1. Concentrations were of the order 200 μg g−1 on a dry-weight basis, which is around six times higher than rich dietary sources such as spinach and parsley; one gram of the algae provides approximately three times the daily adult intake for Vitamin K1. By optimizing the growth conditions (lighting and medium), the productivity was increased fourfold to 22 μg L−1 d−1. Analysis of the nutritional properties of the biomass revealed that it contained high levels of protein (69% (w/w)) and Vitamin B12 (1.5 μg g−1), in addition to the high concentration of phylloquinone. An animal study was performed to evaluate the potential toxicity of the biomass; however, no evidence of acute toxicity was observed even at relatively high addition rates (15% (w/w)). These results support the use of microalgae, specifically A. cylindrica, as a source of phylloquinone." @default.
- W2895948975 created "2018-10-26" @default.
- W2895948975 creator A5006185071 @default.
- W2895948975 creator A5067301856 @default.
- W2895948975 creator A5069374909 @default.
- W2895948975 creator A5083140994 @default.
- W2895948975 creator A5083395422 @default.
- W2895948975 creator A5086630284 @default.
- W2895948975 date "2018-12-01" @default.
- W2895948975 modified "2023-10-01" @default.
- W2895948975 title "Microalgae as a source of vitamin K1" @default.
- W2895948975 cites W1007210389 @default.
- W2895948975 cites W1857537301 @default.
- W2895948975 cites W1923964414 @default.
- W2895948975 cites W1976305047 @default.
- W2895948975 cites W1987045576 @default.
- W2895948975 cites W1987379363 @default.
- W2895948975 cites W1987762566 @default.
- W2895948975 cites W1989482764 @default.
- W2895948975 cites W1990169828 @default.
- W2895948975 cites W1997705682 @default.
- W2895948975 cites W1998903310 @default.
- W2895948975 cites W2007176314 @default.
- W2895948975 cites W2009157617 @default.
- W2895948975 cites W2009791136 @default.
- W2895948975 cites W2014710562 @default.
- W2895948975 cites W2016812307 @default.
- W2895948975 cites W2032942340 @default.
- W2895948975 cites W2034515048 @default.
- W2895948975 cites W2034569948 @default.
- W2895948975 cites W2035207536 @default.
- W2895948975 cites W2037895805 @default.
- W2895948975 cites W2040402109 @default.
- W2895948975 cites W2049120556 @default.
- W2895948975 cites W2050386030 @default.
- W2895948975 cites W2057780573 @default.
- W2895948975 cites W2058443642 @default.
- W2895948975 cites W2062138213 @default.
- W2895948975 cites W2063533285 @default.
- W2895948975 cites W2065676930 @default.
- W2895948975 cites W2065949094 @default.
- W2895948975 cites W2067135771 @default.
- W2895948975 cites W2072503298 @default.
- W2895948975 cites W2072985295 @default.
- W2895948975 cites W2077605590 @default.
- W2895948975 cites W2099956867 @default.
- W2895948975 cites W2100463654 @default.
- W2895948975 cites W2106844272 @default.
- W2895948975 cites W2115045712 @default.
- W2895948975 cites W2116359332 @default.
- W2895948975 cites W2121276791 @default.
- W2895948975 cites W2131200216 @default.
- W2895948975 cites W2138289193 @default.
- W2895948975 cites W2140641009 @default.
- W2895948975 cites W2145050940 @default.
- W2895948975 cites W2151156198 @default.
- W2895948975 cites W2160622117 @default.
- W2895948975 cites W2170010570 @default.
- W2895948975 cites W2170901830 @default.
- W2895948975 cites W2190887955 @default.
- W2895948975 cites W2314268200 @default.
- W2895948975 cites W2323110653 @default.
- W2895948975 cites W2773461647 @default.
- W2895948975 cites W2794863648 @default.
- W2895948975 cites W2803676091 @default.
- W2895948975 cites W957547808 @default.
- W2895948975 doi "https://doi.org/10.1016/j.algal.2018.10.008" @default.
- W2895948975 hasPublicationYear "2018" @default.
- W2895948975 type Work @default.
- W2895948975 sameAs 2895948975 @default.
- W2895948975 citedByCount "55" @default.
- W2895948975 countsByYear W28959489752019 @default.
- W2895948975 countsByYear W28959489752020 @default.
- W2895948975 countsByYear W28959489752021 @default.
- W2895948975 countsByYear W28959489752022 @default.
- W2895948975 countsByYear W28959489752023 @default.
- W2895948975 crossrefType "journal-article" @default.
- W2895948975 hasAuthorship W2895948975A5006185071 @default.
- W2895948975 hasAuthorship W2895948975A5067301856 @default.
- W2895948975 hasAuthorship W2895948975A5069374909 @default.
- W2895948975 hasAuthorship W2895948975A5083140994 @default.
- W2895948975 hasAuthorship W2895948975A5083395422 @default.
- W2895948975 hasAuthorship W2895948975A5086630284 @default.
- W2895948975 hasConcept C2776940978 @default.
- W2895948975 hasConcept C39432304 @default.
- W2895948975 hasConcept C55493867 @default.
- W2895948975 hasConcept C86803240 @default.
- W2895948975 hasConcept C87355193 @default.
- W2895948975 hasConceptScore W2895948975C2776940978 @default.
- W2895948975 hasConceptScore W2895948975C39432304 @default.
- W2895948975 hasConceptScore W2895948975C55493867 @default.
- W2895948975 hasConceptScore W2895948975C86803240 @default.
- W2895948975 hasConceptScore W2895948975C87355193 @default.
- W2895948975 hasFunder F4320334704 @default.
- W2895948975 hasLocation W28959489751 @default.
- W2895948975 hasOpenAccess W2895948975 @default.
- W2895948975 hasPrimaryLocation W28959489751 @default.
- W2895948975 hasRelatedWork W115420553 @default.