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• W2895953552 abstract "This review compared the clinical results of transepithelial corneal crosslinking (CXL) to epithelium-off (epi-off) CXL in progressive corneal ectasia using a metaanalysis. The Cochrane databases and Medline were searched for randomized controlled trials (RCTs). Seven RCTs involving 505 eyes that met the eligibility criteria were identified. The epi-off CXL group showed significantly better outcomes in postoperative changes in maximum keratometry (K) during 1-year observation periods. Transepithelial CXL resulted in significantly greater post-treatment central corneal thickness and best spectacle-corrected visual acuity (BSCVA). The presence of a postoperative demarcation line was significantly more frequent after epi-off CXL than that after transepithelial CXL. No statistically significant difference was found between other parameters. Although patients in the transepithelial CXL group demonstrated a greater improvement in BSCVA compared with patients in the epi-off CXL group at the 1 year follow-up, transepithelial CXL had less impact on halting progressive corneal ectasia in terms of maximum K than epi-off CXL." @default.
• W2895953552 created "2018-10-26" @default.
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• W2895953552 date "2018-12-01" @default.
• W2895953552 modified "2023-10-14" @default.
• W2895953552 title "Transepithelial versus epithelium-off corneal crosslinking for corneal ectasia" @default.
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• W2895953552 doi "https://doi.org/10.1016/j.jcrs.2018.08.021" @default.
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