FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895960092> ?p ?o ?g. }

• W2895960092 endingPage "619" @default.
• W2895960092 startingPage "605" @default.
• W2895960092 abstract "The impact of crisaborole ointment, a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis (AD), on quality of life (QoL) was assessed in two identically designed phase 3 studies (AD-301: NCT02118766; AD-302: NCT02118792, both at http://www.clinicaltrials.gov ).In both studies, patients aged ≥ 2 years with mild to moderate AD per the Investigator's Static Global Assessment were randomly assigned 2:1 to receive crisaborole or vehicle twice daily for 28 days. QoL was assessed using the Children's Dermatology Life Quality Index (CDLQI) (2-15 years), the Dermatology Life Quality Index (DLQI) (≥ 16 years), and the Dermatitis Family Impact Questionnaire (DFI) (parents/caregivers/family of patients aged 2-17 years). Established QoL score severity bands provided clinical context.Greater mean improvement in QoL was observed in crisaborole-treated patients than in vehicle-treated patients at day 29 [mean change from baseline (∆BL), CDLQI: - 4.6 vs. - 3.0; P < 0.001; DLQI: - 5.2 vs. - 3.5; P = 0.015]. At baseline, more than half the patients had a moderate effect or higher of AD on QoL. At day 29, there was a trend toward more crisaborole- than vehicle-treated patients having small effect to no effect, The QoL of parents/caregivers/family improved more for crisaborole-treated than for vehicle-treated patients (∆BL, DFI: - 3.7 vs. - 2.7; P = 0.003).Crisaborole treatment results in clinically meaningful improvement in QoL for patients and their parents/caregivers/families.AD-301: http://www.clinicaltrials.gov , NCT02118766; AD-302: http://www.clinicaltrials.gov , NCT02118792.Anacor Pharmaceuticals, Inc., a wholly owned subsidiary of Pfizer Inc., New York, NY." @default.
• W2895960092 created "2018-10-26" @default.
• W2895960092 creator A5006964107 @default.
• W2895960092 creator A5011739266 @default.
• W2895960092 creator A5015905197 @default.
• W2895960092 creator A5020095047 @default.
• W2895960092 creator A5038176283 @default.
• W2895960092 creator A5055081212 @default.
• W2895960092 creator A5071907436 @default.
• W2895960092 creator A5080833120 @default.
• W2895960092 date "2018-10-22" @default.
• W2895960092 modified "2023-10-16" @default.
• W2895960092 title "Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families" @default.
• W2895960092 cites W1527957830 @default.
• W2895960092 cites W1557125216 @default.
• W2895960092 cites W1583848026 @default.
• W2895960092 cites W1776228394 @default.
• W2895960092 cites W1850254945 @default.
• W2895960092 cites W1871012760 @default.
• W2895960092 cites W1970250600 @default.
• W2895960092 cites W1974705267 @default.
• W2895960092 cites W1980744320 @default.
• W2895960092 cites W1986489637 @default.
• W2895960092 cites W2003679738 @default.
• W2895960092 cites W2004699952 @default.
• W2895960092 cites W2012434022 @default.
• W2895960092 cites W2016605111 @default.
• W2895960092 cites W2022137053 @default.
• W2895960092 cites W2022597676 @default.
• W2895960092 cites W2030298480 @default.
• W2895960092 cites W2030480507 @default.
• W2895960092 cites W2058562555 @default.
• W2895960092 cites W2066945652 @default.
• W2895960092 cites W2072084501 @default.
• W2895960092 cites W2090735611 @default.
• W2895960092 cites W2096991001 @default.
• W2895960092 cites W2105987609 @default.
• W2895960092 cites W2122930857 @default.
• W2895960092 cites W2135595831 @default.
• W2895960092 cites W2142327072 @default.
• W2895960092 cites W2144661996 @default.
• W2895960092 cites W2155912911 @default.
• W2895960092 cites W2168273675 @default.
• W2895960092 cites W2313828678 @default.
• W2895960092 cites W2399038362 @default.
• W2895960092 cites W2400475175 @default.
• W2895960092 cites W2410446282 @default.
• W2895960092 cites W2418638731 @default.
• W2895960092 cites W2418912185 @default.
• W2895960092 cites W2471976905 @default.
• W2895960092 cites W4230355606 @default.
• W2895960092 cites W4232685799 @default.
• W2895960092 cites W4247682368 @default.
• W2895960092 doi "https://doi.org/10.1007/s13555-018-0263-0" @default.
• W2895960092 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6261115" @default.
• W2895960092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30345457" @default.
• W2895960092 hasPublicationYear "2018" @default.
• W2895960092 type Work @default.
• W2895960092 sameAs 2895960092 @default.
• W2895960092 citedByCount "17" @default.
• W2895960092 countsByYear W28959600922019 @default.
• W2895960092 countsByYear W28959600922020 @default.
• W2895960092 countsByYear W28959600922021 @default.
• W2895960092 countsByYear W28959600922022 @default.
• W2895960092 countsByYear W28959600922023 @default.
• W2895960092 crossrefType "journal-article" @default.
• W2895960092 hasAuthorship W2895960092A5006964107 @default.
• W2895960092 hasAuthorship W2895960092A5011739266 @default.
• W2895960092 hasAuthorship W2895960092A5015905197 @default.
• W2895960092 hasAuthorship W2895960092A5020095047 @default.
• W2895960092 hasAuthorship W2895960092A5038176283 @default.
• W2895960092 hasAuthorship W2895960092A5055081212 @default.
• W2895960092 hasAuthorship W2895960092A5071907436 @default.
• W2895960092 hasAuthorship W2895960092A5080833120 @default.
• W2895960092 hasBestOaLocation W28959600921 @default.
• W2895960092 hasConcept C126322002 @default.
• W2895960092 hasConcept C151730666 @default.
• W2895960092 hasConcept C159110408 @default.
• W2895960092 hasConcept C16005928 @default.
• W2895960092 hasConcept C2776173921 @default.
• W2895960092 hasConcept C2778329239 @default.
• W2895960092 hasConcept C2779134260 @default.
• W2895960092 hasConcept C2779343474 @default.
• W2895960092 hasConcept C2779951463 @default.
• W2895960092 hasConcept C2780699399 @default.
• W2895960092 hasConcept C71924100 @default.
• W2895960092 hasConcept C86803240 @default.
• W2895960092 hasConceptScore W2895960092C126322002 @default.
• W2895960092 hasConceptScore W2895960092C151730666 @default.
• W2895960092 hasConceptScore W2895960092C159110408 @default.
• W2895960092 hasConceptScore W2895960092C16005928 @default.
• W2895960092 hasConceptScore W2895960092C2776173921 @default.
• W2895960092 hasConceptScore W2895960092C2778329239 @default.
• W2895960092 hasConceptScore W2895960092C2779134260 @default.
• W2895960092 hasConceptScore W2895960092C2779343474 @default.
• W2895960092 hasConceptScore W2895960092C2779951463 @default.
• W2895960092 hasConceptScore W2895960092C2780699399 @default.
• W2895960092 hasConceptScore W2895960092C71924100 @default.

• next