Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895967898> ?p ?o ?g. }
- W2895967898 endingPage "259" @default.
- W2895967898 startingPage "235" @default.
- W2895967898 abstract "The blood-brain barrier (BBB) is a dynamic barrier essential for maintaining the microenvironment of the brain. Although the special anatomical features of the BBB determine its protective role for the central nervous system (CNS) from blood-borne neurotoxins, however, the BBB extremely limits the therapeutic efficacy of drugs into the CNS, which greatly hinders the treatment of major brain diseases. This chapter summarized the unique structures of the BBB; described a variety of in vivo and in vitro experimental methods for determining the transport properties of the BBB and the permeability of the BBB to water, ions, and solutes including nutrients, therapeutic agents, and drug carriers; and presented recently developed mathematical models which quantitatively correlate the anatomical structures of the BBB with its barrier functions. Recent findings for modulation of the BBB permeability by chemical and physical stimuli were described. Finally, drug delivery strategies through specific trans-BBB routes were discussed." @default.
- W2895967898 created "2018-10-26" @default.
- W2895967898 creator A5000680941 @default.
- W2895967898 date "2018-01-01" @default.
- W2895967898 modified "2023-10-12" @default.
- W2895967898 title "Transport Across the Blood-Brain Barrier" @default.
- W2895967898 cites W128151115 @default.
- W2895967898 cites W132404485 @default.
- W2895967898 cites W1509766815 @default.
- W2895967898 cites W1567458888 @default.
- W2895967898 cites W1570257195 @default.
- W2895967898 cites W1585640564 @default.
- W2895967898 cites W1588685142 @default.
- W2895967898 cites W1692343830 @default.
- W2895967898 cites W172986521 @default.
- W2895967898 cites W1924595537 @default.
- W2895967898 cites W1937716828 @default.
- W2895967898 cites W1963931253 @default.
- W2895967898 cites W1967081185 @default.
- W2895967898 cites W1967395532 @default.
- W2895967898 cites W1973652084 @default.
- W2895967898 cites W1973714454 @default.
- W2895967898 cites W1974129665 @default.
- W2895967898 cites W1976538215 @default.
- W2895967898 cites W1977779892 @default.
- W2895967898 cites W1977940746 @default.
- W2895967898 cites W1980773166 @default.
- W2895967898 cites W1981425827 @default.
- W2895967898 cites W1985344503 @default.
- W2895967898 cites W1985466356 @default.
- W2895967898 cites W1986105567 @default.
- W2895967898 cites W1987102066 @default.
- W2895967898 cites W1989532943 @default.
- W2895967898 cites W1992987500 @default.
- W2895967898 cites W2004365491 @default.
- W2895967898 cites W2005379074 @default.
- W2895967898 cites W2006632378 @default.
- W2895967898 cites W2006740852 @default.
- W2895967898 cites W2011163792 @default.
- W2895967898 cites W2014712282 @default.
- W2895967898 cites W2017435508 @default.
- W2895967898 cites W2018522439 @default.
- W2895967898 cites W2018950212 @default.
- W2895967898 cites W2019588634 @default.
- W2895967898 cites W2020915539 @default.
- W2895967898 cites W2022047142 @default.
- W2895967898 cites W2024170393 @default.
- W2895967898 cites W2024930301 @default.
- W2895967898 cites W2024955728 @default.
- W2895967898 cites W2027689756 @default.
- W2895967898 cites W2028990042 @default.
- W2895967898 cites W2030201417 @default.
- W2895967898 cites W2031715673 @default.
- W2895967898 cites W2033428940 @default.
- W2895967898 cites W2034077873 @default.
- W2895967898 cites W2035086100 @default.
- W2895967898 cites W2035920357 @default.
- W2895967898 cites W2036502826 @default.
- W2895967898 cites W2036821782 @default.
- W2895967898 cites W2038850485 @default.
- W2895967898 cites W2039079026 @default.
- W2895967898 cites W2040732222 @default.
- W2895967898 cites W2040780080 @default.
- W2895967898 cites W2051306620 @default.
- W2895967898 cites W2053123180 @default.
- W2895967898 cites W2054775178 @default.
- W2895967898 cites W2055233461 @default.
- W2895967898 cites W2056229778 @default.
- W2895967898 cites W2056451525 @default.
- W2895967898 cites W2057454109 @default.
- W2895967898 cites W2061637584 @default.
- W2895967898 cites W2066875055 @default.
- W2895967898 cites W2067733328 @default.
- W2895967898 cites W2068265931 @default.
- W2895967898 cites W2069316295 @default.
- W2895967898 cites W2069506489 @default.
- W2895967898 cites W2070573684 @default.
- W2895967898 cites W2070902035 @default.
- W2895967898 cites W2071547067 @default.
- W2895967898 cites W2073748140 @default.
- W2895967898 cites W2074073922 @default.
- W2895967898 cites W2074401887 @default.
- W2895967898 cites W2076634690 @default.
- W2895967898 cites W2077851646 @default.
- W2895967898 cites W2078169327 @default.
- W2895967898 cites W2078647434 @default.
- W2895967898 cites W2080308953 @default.
- W2895967898 cites W2081765246 @default.
- W2895967898 cites W2081959205 @default.
- W2895967898 cites W2082844918 @default.
- W2895967898 cites W2083230753 @default.
- W2895967898 cites W2083777476 @default.
- W2895967898 cites W2084147384 @default.
- W2895967898 cites W2084256007 @default.
- W2895967898 cites W2084794072 @default.
- W2895967898 cites W2085146964 @default.
- W2895967898 cites W2086235904 @default.
- W2895967898 cites W2088351970 @default.