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- W2895973377 abstract "Episodic-like memory refers to integration of where and when a certain event (what) happened. The glutamatergic neurotransmission, particularly AMPA and NMDA receptors, in the dorsal hippocampus mediates episodic recall. Ketamine is a non-competitive NMDA antagonist with effect on cognitive performance and plasticity. The goal of this study was to evaluate the acute action of ketamine on behavioural and neurochemical aspects of episodic-like memory (WWWhen/ELM task) through immediate-early gene expression (IEG), c-Fos, in the dorsal hippocampus. Animals received saline 0.9% or ketamine at 8 mg/kg or 15 mg/kg (i.p.) immediately after the second sample. Our data indicate that untreated and saline rats integrate the three elements of episodic-like memory. Conversely, animals treated with ketamine showed impairment of ELM formation. In addition, the highest dose of ketamine increased c-Fos expression in dorsal CA1 subregion when compared to saline rats. Our results indicate that the antagonism of NMDA concurrently impair ELM formation of all three aspects of ELM and increase neuronal activation in dorsal CA1." @default.
- W2895973377 created "2018-10-26" @default.
- W2895973377 creator A5010103374 @default.
- W2895973377 creator A5011355004 @default.
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- W2895973377 creator A5047043884 @default.
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- W2895973377 creator A5089002394 @default.
- W2895973377 date "2019-02-01" @default.
- W2895973377 modified "2023-10-17" @default.
- W2895973377 title "Episodic-like memory impairment induced by sub-anaesthetic doses of ketamine" @default.
- W2895973377 cites W1495371383 @default.
- W2895973377 cites W1561736917 @default.
- W2895973377 cites W1797972710 @default.
- W2895973377 cites W1964466640 @default.
- W2895973377 cites W1972880019 @default.
- W2895973377 cites W1973984919 @default.
- W2895973377 cites W1975182501 @default.
- W2895973377 cites W1978427498 @default.
- W2895973377 cites W1980576528 @default.
- W2895973377 cites W1980931983 @default.
- W2895973377 cites W1980944036 @default.
- W2895973377 cites W1981097208 @default.
- W2895973377 cites W1982189461 @default.
- W2895973377 cites W1983540839 @default.
- W2895973377 cites W1983971996 @default.
- W2895973377 cites W1986577155 @default.
- W2895973377 cites W1987136976 @default.
- W2895973377 cites W1992909065 @default.
- W2895973377 cites W1995079626 @default.
- W2895973377 cites W1996642120 @default.
- W2895973377 cites W1997184765 @default.
- W2895973377 cites W2000553921 @default.
- W2895973377 cites W2000916441 @default.
- W2895973377 cites W2003432290 @default.
- W2895973377 cites W2010557264 @default.
- W2895973377 cites W2011073327 @default.
- W2895973377 cites W2011566601 @default.
- W2895973377 cites W2012667903 @default.
- W2895973377 cites W2013591387 @default.
- W2895973377 cites W2014192652 @default.
- W2895973377 cites W2015468244 @default.
- W2895973377 cites W2017242154 @default.
- W2895973377 cites W2018457415 @default.
- W2895973377 cites W2021558843 @default.
- W2895973377 cites W2022036472 @default.
- W2895973377 cites W2024636695 @default.
- W2895973377 cites W2025240013 @default.
- W2895973377 cites W2032739515 @default.
- W2895973377 cites W2033499925 @default.
- W2895973377 cites W2035035416 @default.
- W2895973377 cites W2039736626 @default.
- W2895973377 cites W2047276596 @default.
- W2895973377 cites W2048079797 @default.
- W2895973377 cites W2049191904 @default.
- W2895973377 cites W2052651697 @default.
- W2895973377 cites W2055772777 @default.
- W2895973377 cites W2061818436 @default.
- W2895973377 cites W2062991954 @default.
- W2895973377 cites W2063337155 @default.
- W2895973377 cites W2066280437 @default.
- W2895973377 cites W2067047257 @default.
- W2895973377 cites W2069502544 @default.
- W2895973377 cites W2076669993 @default.
- W2895973377 cites W2084391069 @default.
- W2895973377 cites W2085979356 @default.
- W2895973377 cites W2091108897 @default.
- W2895973377 cites W2094136039 @default.
- W2895973377 cites W2094780410 @default.
- W2895973377 cites W2095047274 @default.
- W2895973377 cites W2096243400 @default.
- W2895973377 cites W2100377190 @default.
- W2895973377 cites W2102411019 @default.
- W2895973377 cites W2103218986 @default.
- W2895973377 cites W2107267593 @default.
- W2895973377 cites W2108466731 @default.
- W2895973377 cites W2113460545 @default.
- W2895973377 cites W2117468449 @default.
- W2895973377 cites W2118443528 @default.
- W2895973377 cites W2121687483 @default.
- W2895973377 cites W2126691904 @default.
- W2895973377 cites W2132039854 @default.
- W2895973377 cites W2141391979 @default.
- W2895973377 cites W2144225695 @default.
- W2895973377 cites W2151082833 @default.
- W2895973377 cites W2155145921 @default.
- W2895973377 cites W2165730296 @default.
- W2895973377 cites W2278853437 @default.
- W2895973377 cites W2517785355 @default.
- W2895973377 cites W2532013417 @default.
- W2895973377 cites W2561477559 @default.
- W2895973377 cites W2747857668 @default.
- W2895973377 cites W2790275773 @default.
- W2895973377 doi "https://doi.org/10.1016/j.bbr.2018.10.031" @default.
- W2895973377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30359643" @default.
- W2895973377 hasPublicationYear "2019" @default.
- W2895973377 type Work @default.