FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895974223> ?p ?o ?g. }

• W2895974223 abstract "Many biologists appeal to the so-called Krogh principle when justifying their choice of experimental organisms. The principle states that “for a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied”. Despite its popularity, the principle is often critiqued for implying unwarranted generalizations from optimal models. We argue that the Krogh principle should be interpreted in relation to the historical and scientific contexts in which it has been developed and used. We interpret the Krogh Principle as a heuristic, i.e., as a recommendation to approach biological problems through organisms where a specific trait or physiological mechanism is expected to be most distinctively displayed or most experimentally accessible. We designate these organisms “Krogh organisms”. We clarify the differences between uses of model organisms and non-standard Krogh organisms. Among these is the use of Krogh organisms as “negative models” in biomedical research, where organisms are chosen for their dissimilarity to human physiology. Importantly, the representational scope of Krogh organisms and the generalizability of their characteristics are not fixed or assumed but explored through experimental studies. Research on Krogh organisms is steeped in the comparative method characteristic of zoology and comparative physiology, in which studies of biological variation produce insights into general physiological constraints. Accordingly, we conclude that the Krogh principle exemplifies the advantages of studying biological variation as a strategy to produce generalizable insights." @default.
• W2895974223 created "2018-10-26" @default.
• W2895974223 creator A5027303084 @default.
• W2895974223 creator A5046684743 @default.
• W2895974223 creator A5076296056 @default.
• W2895974223 creator A5090307601 @default.
• W2895974223 date "2018-10-31" @default.
• W2895974223 modified "2023-10-18" @default.
• W2895974223 title "‘Extreme’ organisms and the problem of generalization: interpreting the Krogh principle" @default.
• W2895974223 cites W1558718790 @default.
• W2895974223 cites W1641900861 @default.
• W2895974223 cites W1722075694 @default.
• W2895974223 cites W1921602575 @default.
• W2895974223 cites W1931924338 @default.
• W2895974223 cites W1963546384 @default.
• W2895974223 cites W1964109002 @default.
• W2895974223 cites W1964237471 @default.
• W2895974223 cites W1966649200 @default.
• W2895974223 cites W1969606502 @default.
• W2895974223 cites W1973182116 @default.
• W2895974223 cites W1974038477 @default.
• W2895974223 cites W1980438077 @default.
• W2895974223 cites W1983883185 @default.
• W2895974223 cites W1989589708 @default.
• W2895974223 cites W1999735373 @default.
• W2895974223 cites W2016537883 @default.
• W2895974223 cites W2030932194 @default.
• W2895974223 cites W2044026743 @default.
• W2895974223 cites W2045113466 @default.
• W2895974223 cites W2045423027 @default.
• W2895974223 cites W2047646247 @default.
• W2895974223 cites W2047978220 @default.
• W2895974223 cites W2050159685 @default.
• W2895974223 cites W2055405512 @default.
• W2895974223 cites W2055993926 @default.
• W2895974223 cites W2060057848 @default.
• W2895974223 cites W2060255191 @default.
• W2895974223 cites W2070681860 @default.
• W2895974223 cites W2074867712 @default.
• W2895974223 cites W2082637576 @default.
• W2895974223 cites W2092844180 @default.
• W2895974223 cites W2092895754 @default.
• W2895974223 cites W2109036530 @default.
• W2895974223 cites W2114837299 @default.
• W2895974223 cites W2116991587 @default.
• W2895974223 cites W2117449825 @default.
• W2895974223 cites W2118662008 @default.
• W2895974223 cites W2133226615 @default.
• W2895974223 cites W2142202282 @default.
• W2895974223 cites W2142995785 @default.
• W2895974223 cites W2144459863 @default.
• W2895974223 cites W2148254275 @default.
• W2895974223 cites W2152652033 @default.
• W2895974223 cites W2167975995 @default.
• W2895974223 cites W2178459098 @default.
• W2895974223 cites W224768113 @default.
• W2895974223 cites W2251853835 @default.
• W2895974223 cites W2324892546 @default.
• W2895974223 cites W2334805876 @default.
• W2895974223 cites W2408943862 @default.
• W2895974223 cites W2494893890 @default.
• W2895974223 cites W2528397964 @default.
• W2895974223 cites W30298870 @default.
• W2895974223 cites W4239578492 @default.
• W2895974223 cites W4241984366 @default.
• W2895974223 cites W4243454840 @default.
• W2895974223 cites W4300433821 @default.
• W2895974223 cites W8550698 @default.
• W2895974223 doi "https://doi.org/10.1007/s40656-018-0231-0" @default.
• W2895974223 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6208786" @default.
• W2895974223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30382416" @default.
• W2895974223 hasPublicationYear "2018" @default.
• W2895974223 type Work @default.
• W2895974223 sameAs 2895974223 @default.
• W2895974223 citedByCount "25" @default.
• W2895974223 countsByYear W28959742232019 @default.
• W2895974223 countsByYear W28959742232020 @default.
• W2895974223 countsByYear W28959742232021 @default.
• W2895974223 countsByYear W28959742232022 @default.
• W2895974223 countsByYear W28959742232023 @default.
• W2895974223 crossrefType "journal-article" @default.
• W2895974223 hasAuthorship W2895974223A5027303084 @default.
• W2895974223 hasAuthorship W2895974223A5046684743 @default.
• W2895974223 hasAuthorship W2895974223A5076296056 @default.
• W2895974223 hasAuthorship W2895974223A5090307601 @default.
• W2895974223 hasBestOaLocation W28959742231 @default.
• W2895974223 hasConcept C111472728 @default.
• W2895974223 hasConcept C138496976 @default.
• W2895974223 hasConcept C138885662 @default.
• W2895974223 hasConcept C15744967 @default.
• W2895974223 hasConcept C177148314 @default.
• W2895974223 hasConcept C18903297 @default.
• W2895974223 hasConcept C199360897 @default.
• W2895974223 hasConcept C25343380 @default.
• W2895974223 hasConcept C27158222 @default.
• W2895974223 hasConcept C2778012447 @default.
• W2895974223 hasConcept C2780586970 @default.
• W2895974223 hasConcept C41008148 @default.
• W2895974223 hasConcept C77088390 @default.
• W2895974223 hasConcept C77805123 @default.

• next