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- W2895975523 abstract "Objective: We examined the utility of the Spanish English Neuropsychological Assessment Scale (SENAS) in identifying and tracking Alzheimer’s disease (AD) in Latinos destined to develop autosomal dominant AD (ADAD) relative to a group of normal elderly Latinos. Background: Latinos are a growing population in the U.S. in which our ability to diagnose and track AD is limited by linguistic, educational, and cultural factors. Design/Methods: The SENAS was administered to Latinos in the population-based Los Angeles Latino Eye study (LALES) and to persons at-risk for inheriting pathogenic mutations causing ADAD. Pearson’s correlations of test scores with age (LALES) and with age adjusted for family-specific age of dementia diagnosis (ADAD) were performed. Using the Fisher r-to-z transformation, differences between the correlation coefficients in the two populations were examined. Results: 326 subjects in the LALES study and 20 ADAD mutation carriers were included. Age was negatively correlated with all SENAS subscales in the LALES population including tests of naming, word list recall, non-verbal recall (r = − 0.228, p Conclusions: Despite the small sample size in the ADAD group, our results suggest that delayed recall of non-verbal material on the SENAS may be useful in identifying and tracking memory problems in AD and differentiating them from the effects of aging in the Latino population. Study Supported by: NIH U01 AG-051218, P50 AG-005142, NEI EY-11753, K08 AG-22228 Disclosure: Dr. Ringman has nothing to disclose. Dr. Medina has nothing to disclose. Dr. Chui has nothing to disclose. Dr. Segal-Gidan has nothing to disclose. Dr. Chui has nothing to disclose." @default.
- W2895975523 created "2018-10-26" @default.
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- W2895975523 date "2018-04-10" @default.
- W2895975523 modified "2023-09-26" @default.
- W2895975523 title "Effects of Age on the Spanish English Neuropsychological Assessment Scale in Normal Elderly and Autosomal Dominant Alzheimer’s disease (P5.182)" @default.
- W2895975523 hasPublicationYear "2018" @default.
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