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- W2895977973 abstract "We investigated the pathogenesis of chronic renal fibrosis in cats and dogs using immunohistochemistry. We used the avidin-biotin complex peroxidase (ABC-P) method with antibodies against transforming growth factor-β1, cytokeratin, E-cadherin, S100A4, alpha-smooth muscle actin, vimentin and nestin to determine whether tubule epithelial cells had undergone epithelial-mesenchymal transformation (EMT) that resulted in loss of epithelial cells and an increased number of mesenchymal cells. Although nephrosis was more common in dogs, nephritis was more common in cats; these pathologies developed in both kidneys. We found that EMT participated in the pathogenesis of renal fibrosis in both dogs and cats." @default.
- W2895977973 created "2018-10-26" @default.
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- W2895977973 date "2018-10-17" @default.
- W2895977973 modified "2023-10-17" @default.
- W2895977973 title "Comparison of renal lesions in cats and dogs using pathomorphological and ımmunohistochemical methods" @default.
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- W2895977973 doi "https://doi.org/10.1080/10520295.2018.1522670" @default.
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