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- W2896015003 abstract "Abstract Aim Antineutrophil cytoplasmic antibody‐associated vasculitides ( AAV ) are a group of small vessel vasculitis with systemic presentations and considerable morbidity and mortality. Pregnancy in these patients poses a significant therapeutic challenge. There is limited published literature regarding pregnancy in AAV . Methods Two cases of successful pregnancy outcomes in patients with active AAV are described. A systematic review was conducted on the lines of the PRISMA statement for conducting systemic reviews: PubMed (inception of PubMed until 30 April 2017, English language only) and EmBase databases were searched using the following terms: ‘pregnancy’ AND ‘ ANCA associated vasculitis’ OR ‘granulomatosis with polyangiitis’ OR ‘eosinophilic granulomatosis with polyangiitis’ OR ‘microscopic polyangiitis’ OR ‘Churg‐Strauss syndrome’ OR ‘Wegener's granulomatosis’. Results One hundred and thirty‐seven pregnancies were documented in 110 patients of AAV . Vasculitis diagnosis was made before pregnancy in 69, during pregnancy in 32 and after pregnancy in 9 patients. Mean age at the time of pregnancy was 29.3 ± 5.3 years. There were 91 term pregnancies, 28 were preterm pregnancies, 15 abortions and 3 still births; 78 had normal delivery and 26 had caesarian section. Conclusion Successful pregnancies have been reported in AAV patients." @default.
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- W2896015003 date "2018-09-01" @default.
- W2896015003 modified "2023-10-14" @default.
- W2896015003 title "Successful treatment outcomes in pregnant patients with ANCA-associated vasculitides: A systematic review of literature" @default.
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- W2896015003 doi "https://doi.org/10.1111/1756-185x.13342" @default.
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