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• W2896028828 abstract "<b><i>Background:</i></b> Accumulating data suggest a crucial role of the intestinal microbiota in the development and progression of neurodegenerative diseases. More recently, emerging reports have revealed an association between intestinal microbiota dysfunctions and dementia, a debilitating multifactorial disorder, characterized by progressive deterioration of cognition and behavior that interferes with the social and professional life of the sufferer. However, the mechanisms of this association are not fully understood. <b><i>Summary:</i></b> In this review, I discuss recent data that suggest mechanisms of cross-talk between intestinal microbiota dysfunction and the brain that underlie the development of dementia. Potential therapeutic options for dementia are also discussed. The pleiotropic signaling of the metabolic products of the intestinal microbiota together with their specific roles in the maintenance of both the intestinal and blood-brain barriers as well as regulation of local, distant, and circulating immunocytes, and enteric, visceral, and central neural functions are integral to a healthy gut and brain. <b><i>Key Messages:</i></b> Research investigating the effect of intestinal microbiota dysfunctions on brain health should focus on multiple interrelated systems involving local and central neuroendocrine, immunocyte, and neural signaling of microbial products and transmitters and neurohumoral cells that not only maintain intestinal, but also blood brain-barrier integrity. The change in intestinal microbiome/dysbiome repertoire is crucial to the development of dementia." @default.
• W2896028828 created "2018-10-26" @default.
• W2896028828 creator A5066123416 @default.
• W2896028828 date "2018-10-18" @default.
• W2896028828 modified "2023-10-16" @default.
• W2896028828 title "Current Perspectives and Mechanisms of Relationship between Intestinal Microbiota Dysfunction and Dementia: A Review" @default.
• W2896028828 cites W137926846 @default.
• W2896028828 cites W1504633903 @default.
• W2896028828 cites W1526611045 @default.
• W2896028828 cites W1540257283 @default.
• W2896028828 cites W1561114541 @default.
• W2896028828 cites W1588950918 @default.
• W2896028828 cites W1707143272 @default.
• W2896028828 cites W1729818254 @default.
• W2896028828 cites W1768927256 @default.
• W2896028828 cites W1891884171 @default.
• W2896028828 cites W1948266836 @default.
• W2896028828 cites W1962263973 @default.
• W2896028828 cites W1964791019 @default.
• W2896028828 cites W1965007123 @default.
• W2896028828 cites W1965809997 @default.
• W2896028828 cites W1966217983 @default.
• W2896028828 cites W1970652088 @default.
• W2896028828 cites W1972237932 @default.
• W2896028828 cites W1976203166 @default.
• W2896028828 cites W1976544976 @default.
• W2896028828 cites W1977328678 @default.
• W2896028828 cites W1977823998 @default.
• W2896028828 cites W1980872339 @default.
• W2896028828 cites W1981715127 @default.
• W2896028828 cites W1983370283 @default.
• W2896028828 cites W1984891266 @default.
• W2896028828 cites W1986711635 @default.
• W2896028828 cites W1991078281 @default.
• W2896028828 cites W1994190235 @default.
• W2896028828 cites W1996736315 @default.
• W2896028828 cites W2006612335 @default.
• W2896028828 cites W2007197481 @default.
• W2896028828 cites W2008087433 @default.
• W2896028828 cites W2008649582 @default.
• W2896028828 cites W2010607123 @default.
• W2896028828 cites W2011071982 @default.
• W2896028828 cites W2014632252 @default.
• W2896028828 cites W2018708829 @default.
• W2896028828 cites W2021133027 @default.
• W2896028828 cites W2021605170 @default.
• W2896028828 cites W2024816116 @default.
• W2896028828 cites W2025221802 @default.
• W2896028828 cites W2027183895 @default.
• W2896028828 cites W2036162802 @default.
• W2896028828 cites W2037921023 @default.
• W2896028828 cites W2038769845 @default.
• W2896028828 cites W2040509902 @default.
• W2896028828 cites W2041927083 @default.
• W2896028828 cites W2042433863 @default.
• W2896028828 cites W2049127413 @default.
• W2896028828 cites W2049971830 @default.
• W2896028828 cites W2058974013 @default.
• W2896028828 cites W2060129459 @default.
• W2896028828 cites W2060189209 @default.
• W2896028828 cites W2067689880 @default.
• W2896028828 cites W2067722007 @default.
• W2896028828 cites W2069016882 @default.
• W2896028828 cites W2071384955 @default.
• W2896028828 cites W2071599468 @default.
• W2896028828 cites W2074044574 @default.
• W2896028828 cites W2079861976 @default.
• W2896028828 cites W2080946103 @default.
• W2896028828 cites W2083118719 @default.
• W2896028828 cites W2083119809 @default.
• W2896028828 cites W2085175109 @default.
• W2896028828 cites W2086037905 @default.
• W2896028828 cites W2091706675 @default.
• W2896028828 cites W2092474583 @default.
• W2896028828 cites W2095714788 @default.
• W2896028828 cites W2096362274 @default.
• W2896028828 cites W2096407545 @default.
• W2896028828 cites W2097898022 @default.
• W2896028828 cites W2098661964 @default.
• W2896028828 cites W2100011299 @default.
• W2896028828 cites W2100093202 @default.
• W2896028828 cites W2100606329 @default.
• W2896028828 cites W2100628038 @default.
• W2896028828 cites W2102761280 @default.
• W2896028828 cites W2104887526 @default.
• W2896028828 cites W2106142042 @default.
• W2896028828 cites W2107294231 @default.
• W2896028828 cites W2109113634 @default.
• W2896028828 cites W2110673949 @default.
• W2896028828 cites W2110936821 @default.
• W2896028828 cites W2112332398 @default.
• W2896028828 cites W2113822705 @default.
• W2896028828 cites W2113842526 @default.
• W2896028828 cites W2114089110 @default.
• W2896028828 cites W2116160359 @default.
• W2896028828 cites W2117000810 @default.
• W2896028828 cites W2117029190 @default.
• W2896028828 cites W2117584263 @default.

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