FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896028870> ?p ?o ?g. }

• W2896028870 abstract "Amnestic mild cognitive impairment (aMCI) is considered a risk state for the development of dementia due to Alzheimer’s disease. It is also a period in which interventions may be most effective in slowing progression to dementia. Computerized cognitive training and increased physical activity have shown to be among the most promising interventions. However, current evidence from randomized controlled trials comparing cognitive training, physical activity, and an active control is inconsistent. Furthermore, the neural mechanisms underlying these interventions are currently unclear. The objective of the current pilot study is to explore the feasibility of a trial investigating the impact of computerized cognitive training, yoga, and an active control intervention (wellness education) in individuals with aMCI by conducting a group-randomized, multisite, parallel, three-arm pilot study. We will establish preliminary effect sizes regarding the association of each intervention with neuroimaging and cognitive and participant-reported measures. We also aim to estimate the strength of association between the various outcomes. The current trial aims to recruit 75 people with aMCI and their 75 cognitively healthy care partners through clinics and senior care facilities. The initial intervention will last 10 days and will consist of 1 h daily of the assigned intervention i.e., (yoga, computerized cognitive training, or wellness education) combined with 1 h of memory compensation training and 1 h of support groups. Twenty-five participants will be group-randomized to each arm using a random number generator. Study staff and participants will be kept blind until recruitment is complete for each group. After the initial two-week intervention, participants will continue the assigned intervention for 24 weeks. Outcome measures are: functional connectivity and cerebral perfusion as assessed by magnetic resonance imaging; cognition; daily functioning; mood; anxiety; self-efficacy; caregiver burden; quality of life; and study feasibility including recruitment and retention rates. This pilot trial aims to investigate the feasibility of a trial studying the impact of computerized cognitive training, yoga, and an active control intervention in persons with aMCI on MRI-based functional connectivity and cerebral perfusion as well as cognition, daily functioning, mood, anxiety, and quality of life and feasibility? ClinicalTrials.gov, NCT03095170 . Registered on 23 March 2017." @default.
• W2896028870 created "2018-10-26" @default.
• W2896028870 creator A5010765161 @default.
• W2896028870 creator A5017011551 @default.
• W2896028870 creator A5030588426 @default.
• W2896028870 creator A5036381329 @default.
• W2896028870 creator A5038012254 @default.
• W2896028870 creator A5043921358 @default.
• W2896028870 creator A5062632603 @default.
• W2896028870 creator A5064984267 @default.
• W2896028870 creator A5076444858 @default.
• W2896028870 date "2018-10-19" @default.
• W2896028870 modified "2023-10-06" @default.
• W2896028870 title "Physical exercise and cognitive engagement outcomes for mild neurocognitive disorder: a group-randomized pilot trial" @default.
• W2896028870 cites W1480157407 @default.
• W2896028870 cites W1492500529 @default.
• W2896028870 cites W1532921575 @default.
• W2896028870 cites W1745521526 @default.
• W2896028870 cites W1944313983 @default.
• W2896028870 cites W1966213553 @default.
• W2896028870 cites W1970292641 @default.
• W2896028870 cites W1976340853 @default.
• W2896028870 cites W1980542913 @default.
• W2896028870 cites W1989346261 @default.
• W2896028870 cites W1991952617 @default.
• W2896028870 cites W1992079870 @default.
• W2896028870 cites W1998557170 @default.
• W2896028870 cites W2008482125 @default.
• W2896028870 cites W2008934144 @default.
• W2896028870 cites W2014877105 @default.
• W2896028870 cites W2022625505 @default.
• W2896028870 cites W2023358002 @default.
• W2896028870 cites W2026362238 @default.
• W2896028870 cites W2032698104 @default.
• W2896028870 cites W2054024854 @default.
• W2896028870 cites W2057500061 @default.
• W2896028870 cites W2085870059 @default.
• W2896028870 cites W2089868121 @default.
• W2896028870 cites W2094887465 @default.
• W2896028870 cites W2096657471 @default.
• W2896028870 cites W2109527205 @default.
• W2896028870 cites W2112778345 @default.
• W2896028870 cites W2115017507 @default.
• W2896028870 cites W2115300091 @default.
• W2896028870 cites W2122522567 @default.
• W2896028870 cites W2135810292 @default.
• W2896028870 cites W2149627034 @default.
• W2896028870 cites W2149983193 @default.
• W2896028870 cites W2157868610 @default.
• W2896028870 cites W2161480337 @default.
• W2896028870 cites W2582524520 @default.
• W2896028870 cites W2596970083 @default.
• W2896028870 cites W2970972681 @default.
• W2896028870 cites W4236893933 @default.
• W2896028870 cites W4246915303 @default.
• W2896028870 cites W4247665917 @default.
• W2896028870 doi "https://doi.org/10.1186/s13063-018-2865-3" @default.
• W2896028870 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6194559" @default.
• W2896028870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30340619" @default.
• W2896028870 hasPublicationYear "2018" @default.
• W2896028870 type Work @default.
• W2896028870 sameAs 2896028870 @default.
• W2896028870 citedByCount "12" @default.
• W2896028870 countsByYear W28960288702019 @default.
• W2896028870 countsByYear W28960288702020 @default.
• W2896028870 countsByYear W28960288702021 @default.
• W2896028870 countsByYear W28960288702022 @default.
• W2896028870 countsByYear W28960288702023 @default.
• W2896028870 crossrefType "journal-article" @default.
• W2896028870 hasAuthorship W2896028870A5010765161 @default.
• W2896028870 hasAuthorship W2896028870A5017011551 @default.
• W2896028870 hasAuthorship W2896028870A5030588426 @default.
• W2896028870 hasAuthorship W2896028870A5036381329 @default.
• W2896028870 hasAuthorship W2896028870A5038012254 @default.
• W2896028870 hasAuthorship W2896028870A5043921358 @default.
• W2896028870 hasAuthorship W2896028870A5062632603 @default.
• W2896028870 hasAuthorship W2896028870A5064984267 @default.
• W2896028870 hasAuthorship W2896028870A5076444858 @default.
• W2896028870 hasBestOaLocation W28960288701 @default.
• W2896028870 hasConcept C118552586 @default.
• W2896028870 hasConcept C141071460 @default.
• W2896028870 hasConcept C14216870 @default.
• W2896028870 hasConcept C142724271 @default.
• W2896028870 hasConcept C168563851 @default.
• W2896028870 hasConcept C169900460 @default.
• W2896028870 hasConcept C172467417 @default.
• W2896028870 hasConcept C1862650 @default.
• W2896028870 hasConcept C27415008 @default.
• W2896028870 hasConcept C2779134260 @default.
• W2896028870 hasConcept C2779483572 @default.
• W2896028870 hasConcept C2779602242 @default.
• W2896028870 hasConcept C2780665704 @default.
• W2896028870 hasConcept C70410870 @default.
• W2896028870 hasConcept C71924100 @default.
• W2896028870 hasConcept C99508421 @default.
• W2896028870 hasConceptScore W2896028870C118552586 @default.
• W2896028870 hasConceptScore W2896028870C141071460 @default.
• W2896028870 hasConceptScore W2896028870C14216870 @default.
• W2896028870 hasConceptScore W2896028870C142724271 @default.
• W2896028870 hasConceptScore W2896028870C168563851 @default.

• next