Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896033908> ?p ?o ?g. }
- W2896033908 endingPage "7003" @default.
- W2896033908 startingPage "6995" @default.
- W2896033908 abstract "Noncovalent interactions between single-stranded DNA (ssDNA) oligonucleotides and single wall carbon nanotubes (SWNTs) have provided a unique class of tunable chemistries for a variety of applications. However, mechanistic insight into both the photophysical and intermolecular phenomena underlying their utility is lacking, which results in obligate heuristic approaches for producing ssDNA–SWNT based technologies. In this work, we present an ultrasensitive “turn-on” nanosensor for neuromodulators dopamine and norepinephrine with strong relative change in fluorescence intensity (ΔF/F0) of up to 3500%, a signal appropriate for in vivo neuroimaging, and uncover the photophysical principles and intermolecular interactions that govern the molecular recognition and fluorescence modulation of this nanosensor synthesized from the spontaneous self-assembly of (GT)6 ssDNA rings on SWNTs. The fluorescence modulation of the ssDNA–SWNT conjugate is shown to exhibit remarkable sensitivity to the ssDNA sequence chemistry, length, and surface density, providing a set of parameters with which to tune nanosensor dynamic range, analyte selectivity and strength of fluorescence turn-on. We employ classical and quantum mechanical molecular dynamics simulations to rationalize our experimental findings. Calculations show that (GT)6 ssDNA form ordered rings around (9,4) SWNTs, inducing periodic surface potentials that modulate exciton recombination lifetimes. Further evidence is presented to elucidate how dopamine analyte binding modulates SWNT fluorescence. We discuss the implications of our findings for SWNT-based molecular imaging applications." @default.
- W2896033908 created "2018-10-26" @default.
- W2896033908 creator A5014916440 @default.
- W2896033908 creator A5026520570 @default.
- W2896033908 creator A5027424609 @default.
- W2896033908 creator A5029247141 @default.
- W2896033908 creator A5045437202 @default.
- W2896033908 creator A5052057370 @default.
- W2896033908 creator A5052590258 @default.
- W2896033908 creator A5064329611 @default.
- W2896033908 date "2018-10-17" @default.
- W2896033908 modified "2023-10-16" @default.
- W2896033908 title "Ultralarge Modulation of Fluorescence by Neuromodulators in Carbon Nanotubes Functionalized with Self-Assembled Oligonucleotide Rings" @default.
- W2896033908 cites W1517705904 @default.
- W2896033908 cites W1551381788 @default.
- W2896033908 cites W1643385821 @default.
- W2896033908 cites W1969089145 @default.
- W2896033908 cites W1971313361 @default.
- W2896033908 cites W1985175183 @default.
- W2896033908 cites W1989435382 @default.
- W2896033908 cites W1996258924 @default.
- W2896033908 cites W2010833896 @default.
- W2896033908 cites W2014428801 @default.
- W2896033908 cites W2015617171 @default.
- W2896033908 cites W2021162631 @default.
- W2896033908 cites W2026632806 @default.
- W2896033908 cites W2027209208 @default.
- W2896033908 cites W2034004207 @default.
- W2896033908 cites W2046500362 @default.
- W2896033908 cites W2057952798 @default.
- W2896033908 cites W2061594297 @default.
- W2896033908 cites W2068932598 @default.
- W2896033908 cites W2092536024 @default.
- W2896033908 cites W2094963548 @default.
- W2896033908 cites W2095426352 @default.
- W2896033908 cites W2103491903 @default.
- W2896033908 cites W2104445191 @default.
- W2896033908 cites W2108581465 @default.
- W2896033908 cites W2109687588 @default.
- W2896033908 cites W2115486268 @default.
- W2896033908 cites W2119480884 @default.
- W2896033908 cites W2119801424 @default.
- W2896033908 cites W2147233111 @default.
- W2896033908 cites W2270889623 @default.
- W2896033908 cites W2287742623 @default.
- W2896033908 cites W2302615100 @default.
- W2896033908 cites W2315513825 @default.
- W2896033908 cites W2320557355 @default.
- W2896033908 cites W2326418822 @default.
- W2896033908 cites W2330407759 @default.
- W2896033908 cites W2330820552 @default.
- W2896033908 cites W2537524035 @default.
- W2896033908 cites W2553353231 @default.
- W2896033908 cites W2595181440 @default.
- W2896033908 cites W2621047921 @default.
- W2896033908 cites W2741642657 @default.
- W2896033908 cites W2745942738 @default.
- W2896033908 cites W2766556003 @default.
- W2896033908 cites W2951981680 @default.
- W2896033908 cites W2952318715 @default.
- W2896033908 doi "https://doi.org/10.1021/acs.nanolett.8b02937" @default.
- W2896033908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6771428" @default.
- W2896033908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30350638" @default.
- W2896033908 hasPublicationYear "2018" @default.
- W2896033908 type Work @default.
- W2896033908 sameAs 2896033908 @default.
- W2896033908 citedByCount "62" @default.
- W2896033908 countsByYear W28960339082019 @default.
- W2896033908 countsByYear W28960339082020 @default.
- W2896033908 countsByYear W28960339082021 @default.
- W2896033908 countsByYear W28960339082022 @default.
- W2896033908 countsByYear W28960339082023 @default.
- W2896033908 crossrefType "journal-article" @default.
- W2896033908 hasAuthorship W2896033908A5014916440 @default.
- W2896033908 hasAuthorship W2896033908A5026520570 @default.
- W2896033908 hasAuthorship W2896033908A5027424609 @default.
- W2896033908 hasAuthorship W2896033908A5029247141 @default.
- W2896033908 hasAuthorship W2896033908A5045437202 @default.
- W2896033908 hasAuthorship W2896033908A5052057370 @default.
- W2896033908 hasAuthorship W2896033908A5052590258 @default.
- W2896033908 hasAuthorship W2896033908A5064329611 @default.
- W2896033908 hasBestOaLocation W28960339082 @default.
- W2896033908 hasConcept C112887158 @default.
- W2896033908 hasConcept C119203544 @default.
- W2896033908 hasConcept C121332964 @default.
- W2896033908 hasConcept C129312508 @default.
- W2896033908 hasConcept C137277065 @default.
- W2896033908 hasConcept C166950319 @default.
- W2896033908 hasConcept C171250308 @default.
- W2896033908 hasConcept C178790620 @default.
- W2896033908 hasConcept C185592680 @default.
- W2896033908 hasConcept C192562407 @default.
- W2896033908 hasConcept C32909587 @default.
- W2896033908 hasConcept C41858301 @default.
- W2896033908 hasConcept C513720949 @default.
- W2896033908 hasConcept C552990157 @default.
- W2896033908 hasConcept C55493867 @default.
- W2896033908 hasConcept C62520636 @default.