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• W2896036671 abstract "Diabetes mellitus is a chronic metabolic disorder associated with persistent increased level of glucose in the blood. According to a report by World Health Organisation (WHO), prevalence of diabetes among adults over 18 years of age had reached to 8.5% in year 2014 which was 4.7% in 1980s. The Prolong increased level of glucose in blood leads to development of microvascular (blindness, nephropathy and neuropathy) and macrovascular (cardiovascular and stroke) degenerative complications because of uncontrolled level of glucose in blood. This also leads to the progression of oxidative stress and affecting metabolic, genetic and haemodynamic system by activation of polyol pathway, protein kinase C pathway, hexosamine pathway and increases advanced glycation end products (AGEs) formation. Diabetes mellitus and its associated complications are one of the major leading causes of mortality worldwide. Various natural products like alkaloids, glycosides, flavonoids, terpenoids and polyphenols are reported for their activity in management of diabetes and its associated diabetic complications. Tannins are systematically studied by many researchers in past few decades for their effect in diabetes and its complications. The present review was designed to compile the data of tannins and their beneficial effects in the management of diabetic complications. Literature search was performed using various dataset like pubmed, EBSCO, proQuest Scopus and selected websites including the National Institutes of Health (NIH) and the World Health Organization (WHO). Globally, more than 400 natural products have been investigated in diabetes and its complications. Tannins are the polyphenolic compounds present in many medicinal plants and various dietary sources like fruits, nuts, grains, spices and beverages. Various reports have shown that compounds like gallic acid, ellagic acid, catechin, epicatechin and procynidins from medicinal plants play major role in controlling progression of diabetes and its related complications by acting on molecular pathways and key targets involved in progression. Many chemists used above mentioned phyto-constituents as a pharmacophore for the developing new chemical entities having higher therapeutic benefits in management of diabetic complications. This review focuses on the role of various tannins in prevention and management of diabetic complications like diabetic nephropathy, diabetic neuropathy, diabetic retinopathy and diabetic cardiomyopathy. It will help researchers to find some leads for the development of new cost effective therapy using dietary source for the management of diabetic complications." @default.
• W2896036671 created "2018-10-26" @default.
• W2896036671 creator A5020888472 @default.
• W2896036671 creator A5063267173 @default.
• W2896036671 date "2019-03-01" @default.
• W2896036671 modified "2023-10-18" @default.
• W2896036671 title "Tannins and vascular complications of Diabetes: An update" @default.
• W2896036671 cites W1106978319 @default.
• W2896036671 cites W1480061376 @default.
• W2896036671 cites W1493866611 @default.
• W2896036671 cites W1562556996 @default.
• W2896036671 cites W1563046067 @default.
• W2896036671 cites W1594541821 @default.
• W2896036671 cites W1901671183 @default.
• W2896036671 cites W1966234811 @default.
• W2896036671 cites W1969035931 @default.
• W2896036671 cites W1971044506 @default.
• W2896036671 cites W1972097754 @default.
• W2896036671 cites W1972699960 @default.
• W2896036671 cites W1975818407 @default.
• W2896036671 cites W1977845454 @default.
• W2896036671 cites W1979030077 @default.
• W2896036671 cites W1984714909 @default.
• W2896036671 cites W1985730135 @default.
• W2896036671 cites W1986025060 @default.
• W2896036671 cites W1986341124 @default.
• W2896036671 cites W1991631628 @default.
• W2896036671 cites W1993121409 @default.
• W2896036671 cites W1994447378 @default.
• W2896036671 cites W1995651519 @default.
• W2896036671 cites W2000663727 @default.
• W2896036671 cites W2001593057 @default.
• W2896036671 cites W2002310525 @default.
• W2896036671 cites W2005506826 @default.
• W2896036671 cites W2007325711 @default.
• W2896036671 cites W2008366132 @default.
• W2896036671 cites W2008676938 @default.
• W2896036671 cites W2015471544 @default.
• W2896036671 cites W2017348898 @default.
• W2896036671 cites W2019784111 @default.
• W2896036671 cites W2019967317 @default.
• W2896036671 cites W2024971132 @default.
• W2896036671 cites W2025438351 @default.
• W2896036671 cites W2029149880 @default.
• W2896036671 cites W2030839384 @default.
• W2896036671 cites W2030972405 @default.
• W2896036671 cites W2032604706 @default.
• W2896036671 cites W2042083327 @default.
• W2896036671 cites W2043250256 @default.
• W2896036671 cites W2043701349 @default.
• W2896036671 cites W2044437167 @default.
• W2896036671 cites W2045625966 @default.
• W2896036671 cites W2050181214 @default.
• W2896036671 cites W2051877749 @default.
• W2896036671 cites W2051884669 @default.
• W2896036671 cites W2054978262 @default.
• W2896036671 cites W2062762789 @default.
• W2896036671 cites W2066774498 @default.
• W2896036671 cites W2067212451 @default.
• W2896036671 cites W2067249617 @default.
• W2896036671 cites W2068881644 @default.
• W2896036671 cites W2069196164 @default.
• W2896036671 cites W2069588809 @default.
• W2896036671 cites W2070785261 @default.
• W2896036671 cites W2071650900 @default.
• W2896036671 cites W2073387253 @default.
• W2896036671 cites W2073483379 @default.
• W2896036671 cites W2073688567 @default.
• W2896036671 cites W2076600725 @default.
• W2896036671 cites W2077547064 @default.
• W2896036671 cites W2079426150 @default.
• W2896036671 cites W2080300033 @default.
• W2896036671 cites W2084972843 @default.
• W2896036671 cites W2088950533 @default.
• W2896036671 cites W2094141085 @default.
• W2896036671 cites W2095529597 @default.
• W2896036671 cites W2098330364 @default.
• W2896036671 cites W2101517449 @default.
• W2896036671 cites W2102703137 @default.
• W2896036671 cites W2108917137 @default.
• W2896036671 cites W2111697536 @default.
• W2896036671 cites W2112762119 @default.
• W2896036671 cites W2113384757 @default.
• W2896036671 cites W2114982232 @default.
• W2896036671 cites W2118836695 @default.
• W2896036671 cites W2119588314 @default.
• W2896036671 cites W2120833123 @default.
• W2896036671 cites W2120953129 @default.
• W2896036671 cites W2125527605 @default.
• W2896036671 cites W2126949422 @default.
• W2896036671 cites W2127105516 @default.
• W2896036671 cites W2129246117 @default.
• W2896036671 cites W2130830311 @default.
• W2896036671 cites W2132378029 @default.
• W2896036671 cites W2133186334 @default.
• W2896036671 cites W2136262455 @default.
• W2896036671 cites W2138235467 @default.
• W2896036671 cites W2141675212 @default.

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