Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896039586> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2896039586 endingPage "2431" @default.
- W2896039586 startingPage "2424" @default.
- W2896039586 abstract "Abstract Background Cetuximab combined with chemoradiotherapy chemotherapy is the standard therapy for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC). However, survival benefit is limited. The purpose of this study was to investigate the expression of epiregulin (EREG) and amphiregulin (AREG) , as predictive prognostic markers for the efficacy of cetuximab combined with chemotherapy in R/M HNSCC. Methods We conducted a retrospective analysis of 37 patients diagnosed with R/M HNSCC. Tumor samples were analyzed for EREG and AREG mRNA gene expression, and clinical outcomes evaluated. Results Values of EREG and AREG were associated with significantly longer overall survival (OS) ( P = .03 and P = .01, respectively), as well as progression‐free survival (PFS) ( P = .04 and P = .04, respectively). Multivariate analysis revealed that AREG expression was significantly associated with OS and PFS. Conclusions Patients with recurrent/metastatic HNSCC with higher EREG and AREG gene expression appear to benefit more from cetuximab combined with chemoradiotherapy chemotherapy than those with lower expression." @default.
- W2896039586 created "2018-10-26" @default.
- W2896039586 creator A5016815860 @default.
- W2896039586 creator A5040004483 @default.
- W2896039586 creator A5052392647 @default.
- W2896039586 creator A5053051266 @default.
- W2896039586 creator A5082350005 @default.
- W2896039586 creator A5082782744 @default.
- W2896039586 creator A5089141878 @default.
- W2896039586 date "2018-10-10" @default.
- W2896039586 modified "2023-09-26" @default.
- W2896039586 title "Prognostic role of epiregulin/amphiregulin expression in recurrent/metastatic head and neck cancer treated with cetuximab" @default.
- W2896039586 cites W1955304075 @default.
- W2896039586 cites W1996439082 @default.
- W2896039586 cites W2002178408 @default.
- W2896039586 cites W2041343608 @default.
- W2896039586 cites W2041798076 @default.
- W2896039586 cites W2055443426 @default.
- W2896039586 cites W2077902459 @default.
- W2896039586 cites W2112845420 @default.
- W2896039586 cites W2121960517 @default.
- W2896039586 cites W2137697100 @default.
- W2896039586 cites W2168213749 @default.
- W2896039586 cites W2320041709 @default.
- W2896039586 cites W2341933843 @default.
- W2896039586 cites W2613669325 @default.
- W2896039586 doi "https://doi.org/10.1002/hed.25353" @default.
- W2896039586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30302873" @default.
- W2896039586 hasPublicationYear "2018" @default.
- W2896039586 type Work @default.
- W2896039586 sameAs 2896039586 @default.
- W2896039586 citedByCount "12" @default.
- W2896039586 countsByYear W28960395862019 @default.
- W2896039586 countsByYear W28960395862020 @default.
- W2896039586 countsByYear W28960395862021 @default.
- W2896039586 countsByYear W28960395862022 @default.
- W2896039586 countsByYear W28960395862023 @default.
- W2896039586 crossrefType "journal-article" @default.
- W2896039586 hasAuthorship W2896039586A5016815860 @default.
- W2896039586 hasAuthorship W2896039586A5040004483 @default.
- W2896039586 hasAuthorship W2896039586A5052392647 @default.
- W2896039586 hasAuthorship W2896039586A5053051266 @default.
- W2896039586 hasAuthorship W2896039586A5082350005 @default.
- W2896039586 hasAuthorship W2896039586A5082782744 @default.
- W2896039586 hasAuthorship W2896039586A5089141878 @default.
- W2896039586 hasBestOaLocation W28960395861 @default.
- W2896039586 hasConcept C121608353 @default.
- W2896039586 hasConcept C126322002 @default.
- W2896039586 hasConcept C143998085 @default.
- W2896039586 hasConcept C2776530083 @default.
- W2896039586 hasConcept C2776694085 @default.
- W2896039586 hasConcept C2776833033 @default.
- W2896039586 hasConcept C2777968868 @default.
- W2896039586 hasConcept C2778424827 @default.
- W2896039586 hasConcept C2779438470 @default.
- W2896039586 hasConcept C2779998722 @default.
- W2896039586 hasConcept C2780806702 @default.
- W2896039586 hasConcept C502942594 @default.
- W2896039586 hasConcept C509974204 @default.
- W2896039586 hasConcept C526805850 @default.
- W2896039586 hasConcept C71924100 @default.
- W2896039586 hasConceptScore W2896039586C121608353 @default.
- W2896039586 hasConceptScore W2896039586C126322002 @default.
- W2896039586 hasConceptScore W2896039586C143998085 @default.
- W2896039586 hasConceptScore W2896039586C2776530083 @default.
- W2896039586 hasConceptScore W2896039586C2776694085 @default.
- W2896039586 hasConceptScore W2896039586C2776833033 @default.
- W2896039586 hasConceptScore W2896039586C2777968868 @default.
- W2896039586 hasConceptScore W2896039586C2778424827 @default.
- W2896039586 hasConceptScore W2896039586C2779438470 @default.
- W2896039586 hasConceptScore W2896039586C2779998722 @default.
- W2896039586 hasConceptScore W2896039586C2780806702 @default.
- W2896039586 hasConceptScore W2896039586C502942594 @default.
- W2896039586 hasConceptScore W2896039586C509974204 @default.
- W2896039586 hasConceptScore W2896039586C526805850 @default.
- W2896039586 hasConceptScore W2896039586C71924100 @default.
- W2896039586 hasFunder F4320334764 @default.
- W2896039586 hasIssue "11" @default.
- W2896039586 hasLocation W28960395861 @default.
- W2896039586 hasLocation W28960395862 @default.
- W2896039586 hasOpenAccess W2896039586 @default.
- W2896039586 hasPrimaryLocation W28960395861 @default.
- W2896039586 hasRelatedWork W1956415942 @default.
- W2896039586 hasRelatedWork W1971164957 @default.
- W2896039586 hasRelatedWork W2014645304 @default.
- W2896039586 hasRelatedWork W2110125130 @default.
- W2896039586 hasRelatedWork W2885726167 @default.
- W2896039586 hasRelatedWork W2896039586 @default.
- W2896039586 hasRelatedWork W2999364333 @default.
- W2896039586 hasRelatedWork W3012537123 @default.
- W2896039586 hasRelatedWork W3032138320 @default.
- W2896039586 hasRelatedWork W3087375045 @default.
- W2896039586 hasVolume "40" @default.
- W2896039586 isParatext "false" @default.
- W2896039586 isRetracted "false" @default.
- W2896039586 magId "2896039586" @default.
- W2896039586 workType "article" @default.