FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896043465> ?p ?o ?g. }

• W2896043465 abstract "The analysis of gene expression patterns during ovarian follicle development will advance our understanding of avian reproductive physiology and make it possible to improve laying performance. To gain insight into the molecular regulation of ovarian development, a systematic profiling of miRNAs and mRNAs at four key stages was conducted, using ovarian tissues from hens at 60 days of age (A), 100 days (B), 140 days-not yet laying (C), and 140 days-laying (D). Comparisons of consecutive stages yielded 73 differentially expressed miRNAs (DEMs) (14 for B vs. A, 8 for C vs. B, and 51 for D vs. C) and 2596 differentially expressed genes (DEGs) (51 for B vs. A, 20 for C vs. B, and 2579 for D vs. C). In addition, 174 DEMs (22 for C vs. A, 74 for D vs. A, and 78 for D vs. B) and 3205 DEGs (118 for C vs. A, 2284 for D vs. A, and 2882 for D vs. B) were identified between nonconsecutive stages. Some DEGs are involved in the Wnt and TGF-beta signaling pathways, which are known to affect ovarian development and ovulation. An integrative analysis of the miRNA and mRNA profiles identified 3166 putative miRNA-mRNA regulatory pairs containing 84 DEMs and 1047 DEGs. Functional annotation of the networks provides strong evidence that the miRNA regulatory networks may play vital roles in ovarian development and ovulation. Ten DEMs and 10 genes were validated by real-time quantitative PCR. The candidate miRNA-mRNA pairs gga-miR-200a-3p-SFRP4, gga-miR-101-3p-BMP5, gga-miR-32-5p-FZD4, and gga-miR-458b-5p-CTNNB1 potentially associated with ovarian development." @default.
• W2896043465 created "2018-10-26" @default.
• W2896043465 creator A5011842448 @default.
• W2896043465 creator A5015189543 @default.
• W2896043465 creator A5031746990 @default.
• W2896043465 creator A5043687065 @default.
• W2896043465 creator A5056709272 @default.
• W2896043465 creator A5086786112 @default.
• W2896043465 creator A5087210747 @default.
• W2896043465 date "2018-10-23" @default.
• W2896043465 modified "2023-10-15" @default.
• W2896043465 title "Dynamic Changes in the Global MicroRNAome and Transcriptome Identify Key Nodes Associated With Ovarian Development in Chickens" @default.
• W2896043465 cites W144423133 @default.
• W2896043465 cites W1498970130 @default.
• W2896043465 cites W1518164493 @default.
• W2896043465 cites W1977932419 @default.
• W2896043465 cites W1984220883 @default.
• W2896043465 cites W1996688443 @default.
• W2896043465 cites W2006683252 @default.
• W2896043465 cites W2014236527 @default.
• W2896043465 cites W2015533701 @default.
• W2896043465 cites W2018831893 @default.
• W2896043465 cites W2021163527 @default.
• W2896043465 cites W2023205001 @default.
• W2896043465 cites W2031371243 @default.
• W2896043465 cites W2035618305 @default.
• W2896043465 cites W2040182688 @default.
• W2896043465 cites W2040851473 @default.
• W2896043465 cites W2053003053 @default.
• W2896043465 cites W2064241974 @default.
• W2896043465 cites W2075957756 @default.
• W2896043465 cites W2080327351 @default.
• W2896043465 cites W2086320165 @default.
• W2896043465 cites W2086517349 @default.
• W2896043465 cites W2093740859 @default.
• W2896043465 cites W2096884048 @default.
• W2896043465 cites W2101288828 @default.
• W2896043465 cites W2110795667 @default.
• W2896043465 cites W2112785261 @default.
• W2896043465 cites W2113705043 @default.
• W2896043465 cites W2119034410 @default.
• W2896043465 cites W2119284420 @default.
• W2896043465 cites W2119974836 @default.
• W2896043465 cites W2120775365 @default.
• W2896043465 cites W2124943870 @default.
• W2896043465 cites W2124985265 @default.
• W2896043465 cites W2125905177 @default.
• W2896043465 cites W2129538822 @default.
• W2896043465 cites W2129584348 @default.
• W2896043465 cites W2130009711 @default.
• W2896043465 cites W2130305733 @default.
• W2896043465 cites W2130959624 @default.
• W2896043465 cites W2135399640 @default.
• W2896043465 cites W2138255346 @default.
• W2896043465 cites W2144656637 @default.
• W2896043465 cites W2154431984 @default.
• W2896043465 cites W2166574880 @default.
• W2896043465 cites W2166830979 @default.
• W2896043465 cites W2169402914 @default.
• W2896043465 cites W2197529162 @default.
• W2896043465 cites W2209943607 @default.
• W2896043465 cites W2304103663 @default.
• W2896043465 cites W2510958198 @default.
• W2896043465 cites W2551025035 @default.
• W2896043465 cites W2768605893 @default.
• W2896043465 doi "https://doi.org/10.3389/fgene.2018.00491" @default.
• W2896043465 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6206165" @default.
• W2896043465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30405698" @default.
• W2896043465 hasPublicationYear "2018" @default.
• W2896043465 type Work @default.
• W2896043465 sameAs 2896043465 @default.
• W2896043465 citedByCount "12" @default.
• W2896043465 countsByYear W28960434652020 @default.
• W2896043465 countsByYear W28960434652021 @default.
• W2896043465 countsByYear W28960434652022 @default.
• W2896043465 countsByYear W28960434652023 @default.
• W2896043465 crossrefType "journal-article" @default.
• W2896043465 hasAuthorship W2896043465A5011842448 @default.
• W2896043465 hasAuthorship W2896043465A5015189543 @default.
• W2896043465 hasAuthorship W2896043465A5031746990 @default.
• W2896043465 hasAuthorship W2896043465A5043687065 @default.
• W2896043465 hasAuthorship W2896043465A5056709272 @default.
• W2896043465 hasAuthorship W2896043465A5086786112 @default.
• W2896043465 hasAuthorship W2896043465A5087210747 @default.
• W2896043465 hasBestOaLocation W28960434651 @default.
• W2896043465 hasConcept C104317684 @default.
• W2896043465 hasConcept C105580179 @default.
• W2896043465 hasConcept C134018914 @default.
• W2896043465 hasConcept C137620995 @default.
• W2896043465 hasConcept C145059251 @default.
• W2896043465 hasConcept C150194340 @default.
• W2896043465 hasConcept C162317418 @default.
• W2896043465 hasConcept C16685009 @default.
• W2896043465 hasConcept C18431079 @default.
• W2896043465 hasConcept C2777702977 @default.
• W2896043465 hasConcept C2778324911 @default.
• W2896043465 hasConcept C2779018089 @default.
• W2896043465 hasConcept C54355233 @default.
• W2896043465 hasConcept C60644358 @default.
• W2896043465 hasConcept C70721500 @default.

• next