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• W2896043706 abstract "Foot-and-mouth disease (FMD) is a contagious viral disease of animals. Multiple serotypes and antigenic variation in the viral genome are probably the factors that reduce control of the disease. Currently, the vaccines employed against FMD use killed virus. The inactivation or killing of the virus makes it less immunogenic and reduces its immunoprophylactic potential. To cope with this situation, the present study was designed, anti-idiotype FMD virus antigen was prepared, and the immunogenic potential of the antigen was compared to that of commercial killed-virus vaccines. The overall results showed that a persistent and strong immune response occurred with anti-idiotype FMD virus antigen. Thus, anti-idiotype FMD virus antigen may serve as a potential surrogate of FMD virus vaccines." @default.
• W2896043706 created "2018-10-26" @default.
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• W2896043706 date "2018-10-31" @default.
• W2896043706 modified "2023-09-26" @default.
• W2896043706 title "Immune Modulatory Potential of Anti-idiotype Antibodies as a Surrogate of Foot-and-Mouth Disease Virus Antigen" @default.
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• W2896043706 doi "https://doi.org/10.1128/msphere.00522-18" @default.
• W2896043706 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6193604" @default.
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