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- W2896066720 abstract "An efficient solvent-free access towards highly substituted pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives has been established through multi-component reaction of 1H‐pyrazolo[3,4‐b]pyridin‐3‐amine, aldehyde, 3-(1H-indol-3-yl)-3-oxopropanenitrile catalyzed by 1,1,3,3-tetramethylguanidine (TMG). The reaction allows the formation of one C−C and two C−N bonds with high yield. The significant features of this solvent-free reaction include mild reaction condition, readily accessible substrates, short reaction time, excellent yield, and broad substrate scopes as well as simple one-pot operation, no column chromatographic purification, which makes this strategy highly attractive." @default.
- W2896066720 created "2018-10-26" @default.
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- W2896066720 date "2018-10-18" @default.
- W2896066720 modified "2023-10-18" @default.
- W2896066720 title "An efficient and solvent-free one-pot multi-component synthesis of novel highly substituted pyrido[2′,3′:3,4]pyrazolo[1,5-<i>a</i>]pyrimidine-3-carbonitrile derivatives catalyzed by tetramethylguanidine" @default.
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- W2896066720 doi "https://doi.org/10.1080/00397911.2018.1514053" @default.
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