FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896072002> ?p ?o ?g. }

• W2896072002 endingPage "1379" @default.
• W2896072002 startingPage "1373" @default.
• W2896072002 abstract "Background/Aim: The banana flower is used for ameliorating urinary disturbance. However, there is limited evidence to support the efficacy or mechanism of action of banana flower against benign prostatic hyperplasia (BPH). In the present study, the anti-BPH activity and mechanisms of banana flower extracts were investigated in vitro and in vivo. Materials and Methods: The banana flower extract is a water-soluble extract obtained by sonication. MTT assay was used to examine whether banana flower extract exhibited cytotoxic effects on BPH-1 cells. The effect of banana flower extract on cell-cycle distribution was examined by flow cytometry. The expression of cell-cycle-regulatory molecules was determined by western blot analysis. Testosterone propionate (TP)-induced rat model of BPH was used to evaluate the anti-BPH activity of banana flower extract in vivo. Results: Banana flower extract reduced epithelial cell line BPH-1 cell viability through cell-cycle arrest at G₁ phase. Moreover, banana flower extract reduced the expression of cyclin D1 and cyclin-dependent kinase 6, while it increased the expression of p53 and p27. Interestingly, banana flower extract suppressed BPH-related inflammatory responses through suppressing cyclo-oxygenase-2 expression and prostaglandin E2 production. Finally, banana flower extract administered orally to male rats reduced prostatic weight and serum dihydrotestosterone level, and improved prostate gland morphology. High-performance liquid chromatography revealed that banana flower extract contains citric acid, taurine, pantothenic acid and nicotinic acid components. In summary, banana flower extract may be used as a therapeutic agent for BPH via anti-proliferative and anti-inflammatory activities." @default.
• W2896072002 created "2018-10-26" @default.
• W2896072002 creator A5008735600 @default.
• W2896072002 creator A5015714457 @default.
• W2896072002 creator A5037250610 @default.
• W2896072002 creator A5048435095 @default.
• W2896072002 creator A5049596761 @default.
• W2896072002 creator A5059442215 @default.
• W2896072002 creator A5070866661 @default.
• W2896072002 date "2018-01-01" @default.
• W2896072002 modified "2023-09-23" @default.
• W2896072002 title "Banana Flower Extract Suppresses Benign Prostatic Hyperplasia by Regulating the Inflammatory Response and Inducing G₁ Cell-cycle Arrest" @default.
• W2896072002 cites W1001609334 @default.
• W2896072002 cites W1974557172 @default.
• W2896072002 cites W1990773600 @default.
• W2896072002 cites W1992842220 @default.
• W2896072002 cites W1995797391 @default.
• W2896072002 cites W2014350583 @default.
• W2896072002 cites W2016381211 @default.
• W2896072002 cites W2030629629 @default.
• W2896072002 cites W2090560818 @default.
• W2896072002 cites W2095219757 @default.
• W2896072002 cites W2116247256 @default.
• W2896072002 cites W2122393586 @default.
• W2896072002 cites W2142480001 @default.
• W2896072002 cites W2144490947 @default.
• W2896072002 cites W2205909516 @default.
• W2896072002 cites W2236444969 @default.
• W2896072002 cites W2291696551 @default.
• W2896072002 cites W2314335495 @default.
• W2896072002 cites W2496792062 @default.
• W2896072002 cites W2525383821 @default.
• W2896072002 cites W2556677434 @default.
• W2896072002 cites W2747559128 @default.
• W2896072002 cites W2767066296 @default.
• W2896072002 cites W2771192361 @default.
• W2896072002 doi "https://doi.org/10.21873/invivo.11389" @default.
• W2896072002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6365740" @default.
• W2896072002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30348691" @default.
• W2896072002 hasPublicationYear "2018" @default.
• W2896072002 type Work @default.
• W2896072002 sameAs 2896072002 @default.
• W2896072002 citedByCount "5" @default.
• W2896072002 countsByYear W28960720022019 @default.
• W2896072002 countsByYear W28960720022020 @default.
• W2896072002 countsByYear W28960720022021 @default.
• W2896072002 countsByYear W28960720022022 @default.
• W2896072002 countsByYear W28960720022023 @default.
• W2896072002 crossrefType "journal-article" @default.
• W2896072002 hasAuthorship W2896072002A5008735600 @default.
• W2896072002 hasAuthorship W2896072002A5015714457 @default.
• W2896072002 hasAuthorship W2896072002A5037250610 @default.
• W2896072002 hasAuthorship W2896072002A5048435095 @default.
• W2896072002 hasAuthorship W2896072002A5049596761 @default.
• W2896072002 hasAuthorship W2896072002A5059442215 @default.
• W2896072002 hasAuthorship W2896072002A5070866661 @default.
• W2896072002 hasBestOaLocation W28960720021 @default.
• W2896072002 hasConcept C105696609 @default.
• W2896072002 hasConcept C1491633281 @default.
• W2896072002 hasConcept C150903083 @default.
• W2896072002 hasConcept C185592680 @default.
• W2896072002 hasConcept C207001950 @default.
• W2896072002 hasConcept C2775976191 @default.
• W2896072002 hasConcept C2780783641 @default.
• W2896072002 hasConcept C29537977 @default.
• W2896072002 hasConcept C53227056 @default.
• W2896072002 hasConcept C55493867 @default.
• W2896072002 hasConcept C62112901 @default.
• W2896072002 hasConcept C86803240 @default.
• W2896072002 hasConcept C98274493 @default.
• W2896072002 hasConceptScore W2896072002C105696609 @default.
• W2896072002 hasConceptScore W2896072002C1491633281 @default.
• W2896072002 hasConceptScore W2896072002C150903083 @default.
• W2896072002 hasConceptScore W2896072002C185592680 @default.
• W2896072002 hasConceptScore W2896072002C207001950 @default.
• W2896072002 hasConceptScore W2896072002C2775976191 @default.
• W2896072002 hasConceptScore W2896072002C2780783641 @default.
• W2896072002 hasConceptScore W2896072002C29537977 @default.
• W2896072002 hasConceptScore W2896072002C53227056 @default.
• W2896072002 hasConceptScore W2896072002C55493867 @default.
• W2896072002 hasConceptScore W2896072002C62112901 @default.
• W2896072002 hasConceptScore W2896072002C86803240 @default.
• W2896072002 hasConceptScore W2896072002C98274493 @default.
• W2896072002 hasIssue "6" @default.
• W2896072002 hasLocation W28960720021 @default.
• W2896072002 hasLocation W28960720022 @default.
• W2896072002 hasLocation W28960720023 @default.
• W2896072002 hasLocation W28960720024 @default.
• W2896072002 hasOpenAccess W2896072002 @default.
• W2896072002 hasPrimaryLocation W28960720021 @default.
• W2896072002 hasRelatedWork W2024411365 @default.
• W2896072002 hasRelatedWork W2109994537 @default.
• W2896072002 hasRelatedWork W2123536860 @default.
• W2896072002 hasRelatedWork W2162489064 @default.
• W2896072002 hasRelatedWork W2355829838 @default.
• W2896072002 hasRelatedWork W2393444966 @default.
• W2896072002 hasRelatedWork W2393801921 @default.
• W2896072002 hasRelatedWork W2394835454 @default.

• next