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• W2896087621 abstract "The existence of fluorescent impurities has been a long-standing obstacle in single-molecule imaging, which results in sample misidentification and higher localization uncertainty. Spectroscopic single-molecule localization microscopy can record the full fluorescent spectrum of every stochastic single-molecule emission event. This capability allows us to quantify the spatial and spectral characteristics of fluorescent impurities introduced by sample preparation steps, based on which we developed a method to effectively separate fluorescent impurities from target molecules." @default.
• W2896087621 created "2018-10-26" @default.
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• W2896087621 date "2018-10-17" @default.
• W2896087621 modified "2023-10-05" @default.
• W2896087621 title "Method to identify and minimize artifacts induced by fluorescent impurities in single-molecule localization microscopy" @default.
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• W2896087621 doi "https://doi.org/10.1117/1.jbo.23.10.106501" @default.
• W2896087621 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6210800" @default.
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