Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896091056> ?p ?o ?g. }
- W2896091056 endingPage "1997" @default.
- W2896091056 startingPage "1989" @default.
- W2896091056 abstract "ABSTRACT Introduction The pharmacological treatment of urinary incontinence and overactive bladder (OAB) has been, for a longer time, based on antimuscarinic agents. In recent years, two other pharmacological principles have been introduced for the treatment of OAB and urgency urinary incontinence: the β3-adrenergic agent mirabegron and botulinum neurotoxin. Meanwhile, there is lack of effective drugs for the treatment of stress incontinence. Areas covered This literature review presents synthetic compounds aimed to treat female urinary incontinence that are in phase II-III clinical development. Expert opinion Antimuscarinic agents will continue to represent the current gold standard for the first-line pharmacological management of OAB and urgency urinary incontinence. The class of β3-agonists will certainly expand with the discovery and clinical development of novel agents. Combination therapy of antimuscarinic agents and β3-agonists could offer an alternative treatment in these patients, including those with symptoms refractory to first-line monotherapy. A huge number of preclinical studies are underway in this field exploring the therapeutic potential of many novel compounds while some have advanced to clinical phases of development." @default.
- W2896091056 created "2018-10-26" @default.
- W2896091056 creator A5022616869 @default.
- W2896091056 creator A5057093776 @default.
- W2896091056 date "2018-10-10" @default.
- W2896091056 modified "2023-09-24" @default.
- W2896091056 title "Managing urinary incontinence in women - a review of new and emerging pharmacotherapy" @default.
- W2896091056 cites W1480537354 @default.
- W2896091056 cites W165002891 @default.
- W2896091056 cites W1717874291 @default.
- W2896091056 cites W1761187655 @default.
- W2896091056 cites W1767633497 @default.
- W2896091056 cites W1800213874 @default.
- W2896091056 cites W1965745177 @default.
- W2896091056 cites W1967312126 @default.
- W2896091056 cites W1970886028 @default.
- W2896091056 cites W1980809057 @default.
- W2896091056 cites W1990679322 @default.
- W2896091056 cites W1995223307 @default.
- W2896091056 cites W2000607329 @default.
- W2896091056 cites W2001932212 @default.
- W2896091056 cites W2002470568 @default.
- W2896091056 cites W2015727883 @default.
- W2896091056 cites W2015770414 @default.
- W2896091056 cites W2016630348 @default.
- W2896091056 cites W2018367620 @default.
- W2896091056 cites W2024958952 @default.
- W2896091056 cites W2027053525 @default.
- W2896091056 cites W2033285271 @default.
- W2896091056 cites W2036683704 @default.
- W2896091056 cites W2038094702 @default.
- W2896091056 cites W2039982019 @default.
- W2896091056 cites W2047081116 @default.
- W2896091056 cites W2053621384 @default.
- W2896091056 cites W2054316901 @default.
- W2896091056 cites W2060522553 @default.
- W2896091056 cites W2061953681 @default.
- W2896091056 cites W2063677232 @default.
- W2896091056 cites W2066331613 @default.
- W2896091056 cites W2073438751 @default.
- W2896091056 cites W2078432986 @default.
- W2896091056 cites W2079533643 @default.
- W2896091056 cites W2082404584 @default.
- W2896091056 cites W2084500740 @default.
- W2896091056 cites W2085174162 @default.
- W2896091056 cites W2091772462 @default.
- W2896091056 cites W2096661844 @default.
- W2896091056 cites W2099140641 @default.
- W2896091056 cites W2114048467 @default.
- W2896091056 cites W2127252378 @default.
- W2896091056 cites W2128421946 @default.
- W2896091056 cites W2138057956 @default.
- W2896091056 cites W2142609868 @default.
- W2896091056 cites W2149307650 @default.
- W2896091056 cites W2153762549 @default.
- W2896091056 cites W2161220011 @default.
- W2896091056 cites W2161321211 @default.
- W2896091056 cites W2169087284 @default.
- W2896091056 cites W2215319445 @default.
- W2896091056 cites W2219616168 @default.
- W2896091056 cites W2251027969 @default.
- W2896091056 cites W2280952275 @default.
- W2896091056 cites W2414723751 @default.
- W2896091056 cites W2432925484 @default.
- W2896091056 cites W2532272909 @default.
- W2896091056 cites W2550378266 @default.
- W2896091056 cites W2556751863 @default.
- W2896091056 cites W2563435054 @default.
- W2896091056 cites W2584772262 @default.
- W2896091056 cites W2587662747 @default.
- W2896091056 cites W2606250578 @default.
- W2896091056 cites W2606797645 @default.
- W2896091056 cites W2624955713 @default.
- W2896091056 cites W2748045110 @default.
- W2896091056 cites W2767686167 @default.
- W2896091056 cites W2772220123 @default.
- W2896091056 cites W2784783440 @default.
- W2896091056 cites W2797487137 @default.
- W2896091056 cites W2806767306 @default.
- W2896091056 cites W3193792793 @default.
- W2896091056 cites W365185848 @default.
- W2896091056 cites W4247181855 @default.
- W2896091056 doi "https://doi.org/10.1080/14656566.2018.1532502" @default.
- W2896091056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30304645" @default.
- W2896091056 hasPublicationYear "2018" @default.
- W2896091056 type Work @default.
- W2896091056 sameAs 2896091056 @default.
- W2896091056 citedByCount "6" @default.
- W2896091056 countsByYear W28960910562019 @default.
- W2896091056 countsByYear W28960910562021 @default.
- W2896091056 countsByYear W28960910562022 @default.
- W2896091056 countsByYear W28960910562023 @default.
- W2896091056 crossrefType "journal-article" @default.
- W2896091056 hasAuthorship W2896091056A5022616869 @default.
- W2896091056 hasAuthorship W2896091056A5057093776 @default.
- W2896091056 hasConcept C121332964 @default.
- W2896091056 hasConcept C126322002 @default.
- W2896091056 hasConcept C126894567 @default.