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- W2896094625 endingPage "114" @default.
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- W2896094625 abstract "The endoplasmic reticulum (ER) is a multifunctional organelle, including secretory protein biogenesis, lipid synthesis, drug metabolism, Ca2+ signalling and so on. Since the ER is a single continuous membrane structure, it includes distinct zones responsible for its different functions. The export of newly synthesized proteins from the ER is facilitated via coat protein complex II (COPII)-coated vesicles, which form in specialized zones within the ER, called the ER exit sites (ERES) or transitional ER. In this review, we highlight recent advances in our understanding of the structural organization of ERES, the correlation between the ERES and Golgi organization, and the faithful cargo transport mechanism from the ERES to the Golgi." @default.
- W2896094625 created "2018-10-26" @default.
- W2896094625 creator A5069249615 @default.
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- W2896094625 date "2018-10-10" @default.
- W2896094625 modified "2023-10-13" @default.
- W2896094625 title "The ER exit sites are specialized ER zones for the transport of cargo proteins from the ER to the Golgi apparatus" @default.
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- W2896094625 doi "https://doi.org/10.1093/jb/mvy080" @default.
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