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- W2896180592 abstract "The adverse neurological effects of tramadol have recently raised attention. The literature pertaining to studying postnatal cerebellar changes induced by prenatal tramadol is very scanty, thus the current study has been designed to improve understanding of the cerebellar oxidative stress-related alterations associated with tramadol administration during pregnancy in this critical period of neuronal differentiation and synaptic development, thereby highlighting the importance of controlling prenatal prescription of opioids and optimizing care for opioid-dependent pregnant women and their infants.Twenty pregnant female rats of Sprague Dawley strains were used in the study. Their offspring were divided into two groups: group I (control group) offspring of mothers given saline; group II offspring of mothers given tramadol from the 10th day (D10) of gestation till D21. The pups were sacrificed on the 7th, 14th and 21st postnatal days. Cerebellar specimens were processed for histomorphometric, immunohistochemical and electron microscopic assessment and were evaluated for various oxidative stress parameters.Tramadol administration during pregnancy caused profound structural abnormalities on the post-natal cerebellar cortex and was associated with oxidative stress evidenced by elevation of lipid peroxidation products and inhibition of antioxidant enzyme activities." @default.
- W2896180592 created "2018-10-26" @default.
- W2896180592 creator A5002150965 @default.
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- W2896180592 date "2018-12-01" @default.
- W2896180592 modified "2023-09-23" @default.
- W2896180592 title "Effect of prenatal tramadol on postnatal cerebellar development: Role of oxidative stress" @default.
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- W2896180592 cites W1964340805 @default.
- W2896180592 cites W1971087529 @default.
- W2896180592 cites W1975324682 @default.
- W2896180592 cites W1983222983 @default.
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- W2896180592 cites W2000055244 @default.
- W2896180592 cites W2001197074 @default.
- W2896180592 cites W2003382388 @default.
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- W2896180592 cites W2021256567 @default.
- W2896180592 cites W2030683471 @default.
- W2896180592 cites W2032696930 @default.
- W2896180592 cites W2034222556 @default.
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- W2896180592 doi "https://doi.org/10.1016/j.jchemneu.2018.10.002" @default.
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