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- W2896367058 abstract "Objective: Pulmonary hypertension and right heart failure are poorprognostic factors in systemic sclerosis (SSc). The effect of coldstress on pulmonary vasospasm was evaluated in some trials butthe results were conflicting. The aim of our study was to determinethe effect of cold stress on right ventricular (RV) functions.Materials and Methods: Twenty-four patients with SSc and24 age and sex-matched healthy controls were enrolled in thestudy. Transthoracic echocardiography (TTE) was performed to allpatients at rest and after peripheral cold exposure. Baseline andafter cold stress test TTE were compared between the groups.Results: Cold exposure induced changes in particularly rightventicular functions. Pulmonary acceleration time was significantlyshortened in the SSc group (118.8±11.7ms vs 111.3±13.7ms,P<0.001). Tricuspid annular plane systolic excurison and RVfractional area change were also decreased after cold exposurein the SSc group. (23.3±1.6mm vs 21.9±1.9 mm, P<0.001;46.3±5.8 vs 44.4±5.8,P= 0.007, consecutively). Left ventricular(LV) functions did not change after cold stress (LV myocardialperformance index (0.42± 0.04 vs 0.42± 0.05), P= 0.748).Conclusion: Peripheral cold exposure caused a reductionin right ventricular functions indicating pulmonary Raynaud’sphenomenon as a possible contributing factor." @default.
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- W2896367058 date "2018-10-31" @default.
- W2896367058 modified "2023-10-17" @default.
- W2896367058 title "The effect of cold stress on right ventricular function in patients with systemic sclerosis" @default.
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- W2896367058 doi "https://doi.org/10.5472/marumj.472397" @default.
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