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• W2896383077 endingPage "200" @default.
• W2896383077 startingPage "169" @default.
• W2896383077 abstract "Rift Valley fever virus (RVFV) is an important emerging zoonotic threat to veterinary and public health with potential to cause a severe socioeconomic impact on people’s livelihoods. The capacity of the virus to spread into new territories by crossing significant natural geographic barriers and re-emerge in endemic regions after long periods of silence, to cause large outbreaks in human and animal populations, constitutes a formidable challenge for public and veterinary health authorities as well as for scientific communities worldwide. In spite of recent advances in research on RVFV pathogenesis, molecular epidemiology, outbreak prediction, and development of new diagnostic tools and vaccines, some fundamental aspects of the epidemiology and ecology of the virus remain elusive. Large outbreaks of RVF are associated with anomalous high rainfalls leading to massive flooding and the resultant swarms of competent mosquito vectors transmitting the virus to a wide range of susceptible vertebrate species. However, the exact mechanism of RVFV natural transmission during interepizootic periods remains largely unknown, including the postulated long-term virus persistence in transovarially infected eggs of floodwater Aedes mosquito species, and the role of wild mammals as reservoirs. The presence of competent mosquito vectors in countries free of RVF, the wide range of mammals susceptible to the virus, the global changes in climate, and increased animal trade and travel are some of the factors that might contribute to international spread. This chapter provides the background to the major outbreaks, molecular biology and epidemiology of RVFV, and overviews aspects of ecology, host and vector range which make the virus a potential global emerging threat." @default.
• W2896383077 created "2018-10-26" @default.
• W2896383077 creator A5018692865 @default.
• W2896383077 creator A5081763388 @default.
• W2896383077 date "2014-01-01" @default.
• W2896383077 modified "2023-10-14" @default.
• W2896383077 title "Rift Valley Fever Virus" @default.
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