FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896418780> ?p ?o ?g. }

• W2896418780 endingPage "1802" @default.
• W2896418780 startingPage "1795" @default.
• W2896418780 abstract "BACKGROUND: Globally, gastric cancer (GC) it is the fourth most common cancer and the third cause of cancer-related deaths. Overexpression of MDM2 and B-RAF appeared to be increased in malignancy and associated with poor prognosis in several human tumours, but their role in gastric cancer remains controversial.&#x0D; AIM: We had investigated the immunohistochemical expression of MDM2 and B-RAF in 136 gastric lesions with/without H. pylori association.&#x0D; MATERIAL AND METHODS: Studied specimens include chronic gastritis (32), intestinal type GC (70), diffuse GC (22) and gastrointestinal stromal tumours (GIST) (12).&#x0D; RESULTS: MDM2 expression increased significantly in intestinal GC compared to other groups (p < 0.001), while B-RAF expression increased significantly in GIST compared to other groups (p < 0.001). H. pylori increased expression of MDM2 in intestinal GC cases but did not affect B-RAF expression. MDM2 expression correlated with high grade of tumor differentiation (p < 0.001), deep invasion (p < 0.05), nodal metastases (p < 0.05) and distant metastases (p < 0.1) in intestinal GC, while B-RAF expression did not correlate with TNM stage (p < 0.1).&#x0D; CONCLUSION: MDM2 up-regulation was more frequent in intestinal GC, while B-RAF up-regulation was more frequent in GIST compared to other groups; MDM2 expression in intestinal GC was correlated with H. pylori association, high grade of differentiation, deep invasion, nodal and distant metastases, meanwhile, B-RAF expression was correlated with high-grade intestinal GC but did not correlate with H. pylori or TNM stage. The possible role of both MDM2 and B-RAF in predicting progression of gastric tumours and prognosis deserves further investigations." @default.
• W2896418780 created "2018-10-26" @default.
• W2896418780 creator A5007261230 @default.
• W2896418780 creator A5020669492 @default.
• W2896418780 creator A5021121554 @default.
• W2896418780 creator A5027753681 @default.
• W2896418780 creator A5037129931 @default.
• W2896418780 creator A5045780846 @default.
• W2896418780 creator A5047233415 @default.
• W2896418780 date "2018-10-10" @default.
• W2896418780 modified "2023-09-25" @default.
• W2896418780 title "Overview of MDM2 and B-RAF Expression in Gastric Lesions" @default.
• W2896418780 cites W1620160353 @default.
• W2896418780 cites W1620765082 @default.
• W2896418780 cites W1757407923 @default.
• W2896418780 cites W1822165403 @default.
• W2896418780 cites W1917735140 @default.
• W2896418780 cites W1966714888 @default.
• W2896418780 cites W1970063611 @default.
• W2896418780 cites W1976295398 @default.
• W2896418780 cites W1983787984 @default.
• W2896418780 cites W1986430836 @default.
• W2896418780 cites W2003349514 @default.
• W2896418780 cites W2003823316 @default.
• W2896418780 cites W2005419662 @default.
• W2896418780 cites W2030035221 @default.
• W2896418780 cites W2030707950 @default.
• W2896418780 cites W2045730983 @default.
• W2896418780 cites W2045776501 @default.
• W2896418780 cites W2048674654 @default.
• W2896418780 cites W2051884958 @default.
• W2896418780 cites W2052275819 @default.
• W2896418780 cites W2058622329 @default.
• W2896418780 cites W2059774006 @default.
• W2896418780 cites W2064470056 @default.
• W2896418780 cites W2065050627 @default.
• W2896418780 cites W2074089133 @default.
• W2896418780 cites W2079106934 @default.
• W2896418780 cites W2091151265 @default.
• W2896418780 cites W2096076701 @default.
• W2896418780 cites W2113537738 @default.
• W2896418780 cites W2118129019 @default.
• W2896418780 cites W2126731289 @default.
• W2896418780 cites W2130680667 @default.
• W2896418780 cites W2140481064 @default.
• W2896418780 cites W2144162491 @default.
• W2896418780 cites W2151439322 @default.
• W2896418780 cites W2159923832 @default.
• W2896418780 cites W2163188200 @default.
• W2896418780 cites W2345131527 @default.
• W2896418780 cites W2408723165 @default.
• W2896418780 cites W2585836024 @default.
• W2896418780 cites W4240198818 @default.
• W2896418780 doi "https://doi.org/10.3889/oamjms.2018.338" @default.
• W2896418780 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6236038" @default.
• W2896418780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30455751" @default.
• W2896418780 hasPublicationYear "2018" @default.
• W2896418780 type Work @default.
• W2896418780 sameAs 2896418780 @default.
• W2896418780 citedByCount "3" @default.
• W2896418780 countsByYear W28964187802021 @default.
• W2896418780 countsByYear W28964187802022 @default.
• W2896418780 crossrefType "journal-article" @default.
• W2896418780 hasAuthorship W2896418780A5007261230 @default.
• W2896418780 hasAuthorship W2896418780A5020669492 @default.
• W2896418780 hasAuthorship W2896418780A5021121554 @default.
• W2896418780 hasAuthorship W2896418780A5027753681 @default.
• W2896418780 hasAuthorship W2896418780A5037129931 @default.
• W2896418780 hasAuthorship W2896418780A5045780846 @default.
• W2896418780 hasAuthorship W2896418780A5047233415 @default.
• W2896418780 hasBestOaLocation W28964187802 @default.
• W2896418780 hasConcept C121608353 @default.
• W2896418780 hasConcept C126322002 @default.
• W2896418780 hasConcept C142724271 @default.
• W2896418780 hasConcept C146357865 @default.
• W2896418780 hasConcept C151730666 @default.
• W2896418780 hasConcept C16930146 @default.
• W2896418780 hasConcept C190283241 @default.
• W2896418780 hasConcept C204232928 @default.
• W2896418780 hasConcept C2775922572 @default.
• W2896418780 hasConcept C2776192174 @default.
• W2896418780 hasConcept C2779399171 @default.
• W2896418780 hasConcept C55493867 @default.
• W2896418780 hasConcept C71924100 @default.
• W2896418780 hasConcept C86803240 @default.
• W2896418780 hasConcept C90924648 @default.
• W2896418780 hasConceptScore W2896418780C121608353 @default.
• W2896418780 hasConceptScore W2896418780C126322002 @default.
• W2896418780 hasConceptScore W2896418780C142724271 @default.
• W2896418780 hasConceptScore W2896418780C146357865 @default.
• W2896418780 hasConceptScore W2896418780C151730666 @default.
• W2896418780 hasConceptScore W2896418780C16930146 @default.
• W2896418780 hasConceptScore W2896418780C190283241 @default.
• W2896418780 hasConceptScore W2896418780C204232928 @default.
• W2896418780 hasConceptScore W2896418780C2775922572 @default.
• W2896418780 hasConceptScore W2896418780C2776192174 @default.
• W2896418780 hasConceptScore W2896418780C2779399171 @default.
• W2896418780 hasConceptScore W2896418780C55493867 @default.

• next