FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896423219> ?p ?o ?g. }

• W2896423219 endingPage "62" @default.
• W2896423219 startingPage "50" @default.
• W2896423219 abstract "Iron is critical for virtually all organisms, yet major questions remain regarding the systems-level understanding of iron in whole cells. Here, we obtained Mossbauer and EPR spectra of Escherichia coli cells prepared under different nutrient iron concentrations, carbon sources, growth phases, and O2 concentrations to better understand their global iron content. We investigated WT cells and those lacking Fur, FtnA, Bfr, and Dps proteins. The coarse-grain iron content of exponentially growing cells consisted of iron-sulfur clusters, variable amounts of nonheme high-spin FeII species, and an unassigned residual quadrupole doublet. The iron in stationary-phase cells was dominated by magnetically ordered FeIII ions due to oxyhydroxide nanoparticles. Analysis of cytosolic extracts by size-exclusion chromatography detected by an online inductively coupled plasma mass spectrometer revealed a low-molecular-mass (LMM) FeII pool consisting of two iron complexes with masses of ∼500 (major) and ∼1300 (minor) Da. They appeared to be high-spin FeII species with mostly oxygen donor ligands, perhaps a few nitrogen donors, and probably no sulfur donors. Surprisingly, the iron content of E. coli and its reactivity with O2 were remarkably similar to those of mitochondria. In both cases, a composed of membrane-bound iron-rich respiratory complexes may protect the LMM FeII pool from reacting with O2 When exponentially growing cells transition to stationary phase, the shield deactivates as metabolic activity declines. Given the universality of oxidative phosphorylation in aerobic biology, the iron content and respiratory shield in other aerobic prokaryotes might be similar to those of E. coli and mitochondria." @default.
• W2896423219 created "2018-10-26" @default.
• W2896423219 creator A5026759330 @default.
• W2896423219 creator A5047681267 @default.
• W2896423219 creator A5053666065 @default.
• W2896423219 creator A5055247081 @default.
• W2896423219 creator A5069253317 @default.
• W2896423219 date "2019-01-01" @default.
• W2896423219 modified "2023-10-15" @default.
• W2896423219 title "Evidence that a respiratory shield in Escherichia coli protects a low-molecular-mass FeII pool from O2-dependent oxidation" @default.
• W2896423219 cites W1494129769 @default.
• W2896423219 cites W1879417451 @default.
• W2896423219 cites W1947935290 @default.
• W2896423219 cites W1963615300 @default.
• W2896423219 cites W1965284073 @default.
• W2896423219 cites W1965397885 @default.
• W2896423219 cites W1968458406 @default.
• W2896423219 cites W1972610941 @default.
• W2896423219 cites W1976279029 @default.
• W2896423219 cites W1982245868 @default.
• W2896423219 cites W1983081312 @default.
• W2896423219 cites W1989178534 @default.
• W2896423219 cites W1993249080 @default.
• W2896423219 cites W1999691755 @default.
• W2896423219 cites W2001055223 @default.
• W2896423219 cites W2004726907 @default.
• W2896423219 cites W2011203802 @default.
• W2896423219 cites W2012609712 @default.
• W2896423219 cites W2017695149 @default.
• W2896423219 cites W2022109900 @default.
• W2896423219 cites W2035594105 @default.
• W2896423219 cites W2038405260 @default.
• W2896423219 cites W2038950831 @default.
• W2896423219 cites W2041807493 @default.
• W2896423219 cites W2048264044 @default.
• W2896423219 cites W2049009393 @default.
• W2896423219 cites W2050540965 @default.
• W2896423219 cites W2052751797 @default.
• W2896423219 cites W2056558444 @default.
• W2896423219 cites W2063719131 @default.
• W2896423219 cites W2071332460 @default.
• W2896423219 cites W2074775358 @default.
• W2896423219 cites W2076190961 @default.
• W2896423219 cites W2081925287 @default.
• W2896423219 cites W2082731101 @default.
• W2896423219 cites W2085773333 @default.
• W2896423219 cites W2097008109 @default.
• W2896423219 cites W2099888935 @default.
• W2896423219 cites W2101128002 @default.
• W2896423219 cites W2102454051 @default.
• W2896423219 cites W2102837720 @default.
• W2896423219 cites W2116137883 @default.
• W2896423219 cites W2123053875 @default.
• W2896423219 cites W2147431408 @default.
• W2896423219 cites W2168303302 @default.
• W2896423219 cites W2228380367 @default.
• W2896423219 cites W2256451570 @default.
• W2896423219 cites W2304936306 @default.
• W2896423219 cites W2345232881 @default.
• W2896423219 cites W2394571638 @default.
• W2896423219 cites W2402068783 @default.
• W2896423219 cites W2487193031 @default.
• W2896423219 cites W2613095160 @default.
• W2896423219 cites W2624650 @default.
• W2896423219 cites W2625087901 @default.
• W2896423219 cites W2766737376 @default.
• W2896423219 cites W2771824445 @default.
• W2896423219 cites W2805739998 @default.
• W2896423219 cites W55796051 @default.
• W2896423219 doi "https://doi.org/10.1074/jbc.ra118.005233" @default.
• W2896423219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6322884" @default.
• W2896423219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30337367" @default.
• W2896423219 hasPublicationYear "2019" @default.
• W2896423219 type Work @default.
• W2896423219 sameAs 2896423219 @default.
• W2896423219 citedByCount "29" @default.
• W2896423219 countsByYear W28964232192019 @default.
• W2896423219 countsByYear W28964232192020 @default.
• W2896423219 countsByYear W28964232192021 @default.
• W2896423219 countsByYear W28964232192022 @default.
• W2896423219 countsByYear W28964232192023 @default.
• W2896423219 crossrefType "journal-article" @default.
• W2896423219 hasAuthorship W2896423219A5026759330 @default.
• W2896423219 hasAuthorship W2896423219A5047681267 @default.
• W2896423219 hasAuthorship W2896423219A5053666065 @default.
• W2896423219 hasAuthorship W2896423219A5055247081 @default.
• W2896423219 hasAuthorship W2896423219A5069253317 @default.
• W2896423219 hasBestOaLocation W28964232191 @default.
• W2896423219 hasConcept C104317684 @default.
• W2896423219 hasConcept C105702510 @default.
• W2896423219 hasConcept C107872376 @default.
• W2896423219 hasConcept C138081364 @default.
• W2896423219 hasConcept C151730666 @default.
• W2896423219 hasConcept C185592680 @default.
• W2896423219 hasConcept C534529494 @default.
• W2896423219 hasConcept C547475151 @default.
• W2896423219 hasConcept C55493867 @default.
• W2896423219 hasConcept C86803240 @default.

• next