Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896445416> ?p ?o ?g. }
- W2896445416 abstract "ABSTRACT Chromatin features are characterized by genome-wide assays for nucleosome location, protein binding sites, 3-dimensional interactions, and modifications to histones and DNA. For example, Assay for Transposase Accessible Chromatin sequencing (ATAC-seq) identifies nucleosome-depleted (open) chromatin, which harbors potentially active gene regulatory sequences; and bisulfite sequencing (BS-seq) quantifies DNA methylation. When two distinct chromatin features like these are assayed separately in populations of cells, it is impossible to determine, with certainty, where the features are coincident in the genome by simply overlaying datasets. Here we describe methyl-ATAC-seq (mATAC-seq), which implements modifications to ATAC-seq, including subjecting the output to BS-seq. Merging these assays into a single protocol identifies the locations of open chromatin, and reveals, unambiguously, the DNA methylation state of the underlying DNA. Such combinatorial methods eliminate the need to perform assays independently and infer where features are coincident." @default.
- W2896445416 created "2018-10-26" @default.
- W2896445416 creator A5001813174 @default.
- W2896445416 creator A5040461926 @default.
- W2896445416 creator A5064371897 @default.
- W2896445416 creator A5086265426 @default.
- W2896445416 date "2018-10-17" @default.
- W2896445416 modified "2023-09-26" @default.
- W2896445416 title "methyl-ATAC-seq measures DNA methylation at accessible chromatin" @default.
- W2896445416 cites W1492083415 @default.
- W2896445416 cites W1522855936 @default.
- W2896445416 cites W1699926620 @default.
- W2896445416 cites W1925000049 @default.
- W2896445416 cites W1964963969 @default.
- W2896445416 cites W1968049436 @default.
- W2896445416 cites W1968931043 @default.
- W2896445416 cites W1970225064 @default.
- W2896445416 cites W1984066495 @default.
- W2896445416 cites W1993022532 @default.
- W2896445416 cites W2003547435 @default.
- W2896445416 cites W2014677321 @default.
- W2896445416 cites W2022587035 @default.
- W2896445416 cites W2022640617 @default.
- W2896445416 cites W2026863186 @default.
- W2896445416 cites W2033788334 @default.
- W2896445416 cites W2043472013 @default.
- W2896445416 cites W2064188460 @default.
- W2896445416 cites W2076154138 @default.
- W2896445416 cites W2082793267 @default.
- W2896445416 cites W2092105616 @default.
- W2896445416 cites W2092170757 @default.
- W2896445416 cites W2093188241 @default.
- W2896445416 cites W2102278945 @default.
- W2896445416 cites W2106340111 @default.
- W2896445416 cites W2110905563 @default.
- W2896445416 cites W2111274140 @default.
- W2896445416 cites W2111801210 @default.
- W2896445416 cites W2116816603 @default.
- W2896445416 cites W2117757143 @default.
- W2896445416 cites W2122097157 @default.
- W2896445416 cites W2123564569 @default.
- W2896445416 cites W2129727138 @default.
- W2896445416 cites W2131374955 @default.
- W2896445416 cites W2133046153 @default.
- W2896445416 cites W2149627698 @default.
- W2896445416 cites W2150194502 @default.
- W2896445416 cites W2150733697 @default.
- W2896445416 cites W2158019017 @default.
- W2896445416 cites W2160315910 @default.
- W2896445416 cites W2167674777 @default.
- W2896445416 cites W2170830174 @default.
- W2896445416 cites W2179438025 @default.
- W2896445416 cites W2281392042 @default.
- W2896445416 cites W2295747532 @default.
- W2896445416 cites W2341539131 @default.
- W2896445416 cites W2385343223 @default.
- W2896445416 cites W2506496078 @default.
- W2896445416 cites W2514448720 @default.
- W2896445416 cites W2562158244 @default.
- W2896445416 cites W2610903912 @default.
- W2896445416 cites W2750416916 @default.
- W2896445416 cites W2797310920 @default.
- W2896445416 cites W2885161527 @default.
- W2896445416 cites W2951912016 @default.
- W2896445416 cites W4247053599 @default.
- W2896445416 doi "https://doi.org/10.1101/445486" @default.
- W2896445416 hasPublicationYear "2018" @default.
- W2896445416 type Work @default.
- W2896445416 sameAs 2896445416 @default.
- W2896445416 citedByCount "0" @default.
- W2896445416 crossrefType "posted-content" @default.
- W2896445416 hasAuthorship W2896445416A5001813174 @default.
- W2896445416 hasAuthorship W2896445416A5040461926 @default.
- W2896445416 hasAuthorship W2896445416A5064371897 @default.
- W2896445416 hasAuthorship W2896445416A5086265426 @default.
- W2896445416 hasBestOaLocation W28964454161 @default.
- W2896445416 hasConcept C104317684 @default.
- W2896445416 hasConcept C121912465 @default.
- W2896445416 hasConcept C141231307 @default.
- W2896445416 hasConcept C150194340 @default.
- W2896445416 hasConcept C176619506 @default.
- W2896445416 hasConcept C190727270 @default.
- W2896445416 hasConcept C41091548 @default.
- W2896445416 hasConcept C51679486 @default.
- W2896445416 hasConcept C54355233 @default.
- W2896445416 hasConcept C552990157 @default.
- W2896445416 hasConcept C64927066 @default.
- W2896445416 hasConcept C67258246 @default.
- W2896445416 hasConcept C70721500 @default.
- W2896445416 hasConcept C83640560 @default.
- W2896445416 hasConcept C84772758 @default.
- W2896445416 hasConcept C86803240 @default.
- W2896445416 hasConceptScore W2896445416C104317684 @default.
- W2896445416 hasConceptScore W2896445416C121912465 @default.
- W2896445416 hasConceptScore W2896445416C141231307 @default.
- W2896445416 hasConceptScore W2896445416C150194340 @default.
- W2896445416 hasConceptScore W2896445416C176619506 @default.
- W2896445416 hasConceptScore W2896445416C190727270 @default.
- W2896445416 hasConceptScore W2896445416C41091548 @default.
- W2896445416 hasConceptScore W2896445416C51679486 @default.