FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896464592> ?p ?o ?g. }

• W2896464592 endingPage "44" @default.
• W2896464592 startingPage "39" @default.
• W2896464592 abstract "Background and aims Leptin (LPT) is associated with unfavourable cardio-metabolic risk profile. Although a number of studies have found a positive association between LPT and insulin resistance (IR), no observational study has evaluated a prospective association to detect a predictive role of LPT in IR. Therefore, the aim of this study was to estimate the role of LPT on the incidence of IR in an 8-year follow-up of a sample of adult men (The Olivetti Heart Study). Methods and results The study included 527 not diabetic men without IR (homeostasis model assessment - HOMA index < 2.77 UI) at baseline. Baseline LPT was significantly and positively associated with HOMA index, body mass index (BMI), waist circumference and blood pressure. At the end of the 8-year follow-up period, a positive and significant association was detected between baseline LPT and changes in HOMA index (r = 0.25, p < 0.01) and incidence of IR (OR: 2.6, 95%CI: 1.9–3.4). This trend was also confirmed after adjustment for potential confounders. In addition, the predictive value of LPT was found in subjects who had not experienced any weight increase over the years, and for normal weight and excess body weight participants, separately. Conclusions The results of this prospective study suggest a predictive role of circulating LPT levels on a reduction of insulin sensitivity over time, independently of main potential confounders, in non-diabetic men without IR at baseline. In addition, in normal weight individuals, LPT levels were associated with development of IR." @default.
• W2896464592 created "2018-10-26" @default.
• W2896464592 creator A5013313808 @default.
• W2896464592 creator A5016207571 @default.
• W2896464592 creator A5018174118 @default.
• W2896464592 creator A5050831033 @default.
• W2896464592 creator A5059847514 @default.
• W2896464592 date "2019-01-01" @default.
• W2896464592 modified "2023-10-17" @default.
• W2896464592 title "Leptin levels predict the development of insulin resistance in a sample of adult men–The Olivetti Heart Study" @default.
• W2896464592 cites W1512068992 @default.
• W2896464592 cites W1963613238 @default.
• W2896464592 cites W1988494023 @default.
• W2896464592 cites W2003867612 @default.
• W2896464592 cites W2006272024 @default.
• W2896464592 cites W2010276550 @default.
• W2896464592 cites W2012425798 @default.
• W2896464592 cites W2030756498 @default.
• W2896464592 cites W2042621509 @default.
• W2896464592 cites W2042893069 @default.
• W2896464592 cites W2044216277 @default.
• W2896464592 cites W2045826482 @default.
• W2896464592 cites W2052151089 @default.
• W2896464592 cites W2054912558 @default.
• W2896464592 cites W2060280485 @default.
• W2896464592 cites W2067242542 @default.
• W2896464592 cites W2069080505 @default.
• W2896464592 cites W2075242060 @default.
• W2896464592 cites W2078904921 @default.
• W2896464592 cites W2099193602 @default.
• W2896464592 cites W2110784606 @default.
• W2896464592 cites W2113808580 @default.
• W2896464592 cites W2125805218 @default.
• W2896464592 cites W2140737925 @default.
• W2896464592 cites W2147788805 @default.
• W2896464592 cites W2164600485 @default.
• W2896464592 cites W2167557672 @default.
• W2896464592 cites W2182150538 @default.
• W2896464592 cites W2217041690 @default.
• W2896464592 cites W2294456253 @default.
• W2896464592 cites W2314772996 @default.
• W2896464592 cites W2334337188 @default.
• W2896464592 cites W2500637672 @default.
• W2896464592 cites W2586160953 @default.
• W2896464592 cites W2730596924 @default.
• W2896464592 cites W2790694726 @default.
• W2896464592 cites W2805508348 @default.
• W2896464592 cites W2885041048 @default.
• W2896464592 doi "https://doi.org/10.1016/j.numecd.2018.10.003" @default.
• W2896464592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30527422" @default.
• W2896464592 hasPublicationYear "2019" @default.
• W2896464592 type Work @default.
• W2896464592 sameAs 2896464592 @default.
• W2896464592 citedByCount "22" @default.
• W2896464592 countsByYear W28964645922019 @default.
• W2896464592 countsByYear W28964645922020 @default.
• W2896464592 countsByYear W28964645922021 @default.
• W2896464592 countsByYear W28964645922022 @default.
• W2896464592 countsByYear W28964645922023 @default.
• W2896464592 crossrefType "journal-article" @default.
• W2896464592 hasAuthorship W2896464592A5013313808 @default.
• W2896464592 hasAuthorship W2896464592A5016207571 @default.
• W2896464592 hasAuthorship W2896464592A5018174118 @default.
• W2896464592 hasAuthorship W2896464592A5050831033 @default.
• W2896464592 hasAuthorship W2896464592A5059847514 @default.
• W2896464592 hasConcept C120665830 @default.
• W2896464592 hasConcept C121332964 @default.
• W2896464592 hasConcept C126322002 @default.
• W2896464592 hasConcept C134018914 @default.
• W2896464592 hasConcept C188816634 @default.
• W2896464592 hasConcept C23131810 @default.
• W2896464592 hasConcept C2776193436 @default.
• W2896464592 hasConcept C2777391703 @default.
• W2896464592 hasConcept C2778535154 @default.
• W2896464592 hasConcept C2780221984 @default.
• W2896464592 hasConcept C2780613262 @default.
• W2896464592 hasConcept C511355011 @default.
• W2896464592 hasConcept C544821477 @default.
• W2896464592 hasConcept C555293320 @default.
• W2896464592 hasConcept C61511704 @default.
• W2896464592 hasConcept C71924100 @default.
• W2896464592 hasConcept C77350462 @default.
• W2896464592 hasConceptScore W2896464592C120665830 @default.
• W2896464592 hasConceptScore W2896464592C121332964 @default.
• W2896464592 hasConceptScore W2896464592C126322002 @default.
• W2896464592 hasConceptScore W2896464592C134018914 @default.
• W2896464592 hasConceptScore W2896464592C188816634 @default.
• W2896464592 hasConceptScore W2896464592C23131810 @default.
• W2896464592 hasConceptScore W2896464592C2776193436 @default.
• W2896464592 hasConceptScore W2896464592C2777391703 @default.
• W2896464592 hasConceptScore W2896464592C2778535154 @default.
• W2896464592 hasConceptScore W2896464592C2780221984 @default.
• W2896464592 hasConceptScore W2896464592C2780613262 @default.
• W2896464592 hasConceptScore W2896464592C511355011 @default.
• W2896464592 hasConceptScore W2896464592C544821477 @default.
• W2896464592 hasConceptScore W2896464592C555293320 @default.
• W2896464592 hasConceptScore W2896464592C61511704 @default.
• W2896464592 hasConceptScore W2896464592C71924100 @default.

• next