FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896465352> ?p ?o ?g. }

• W2896465352 endingPage "6" @default.
• W2896465352 startingPage "1" @default.
• W2896465352 abstract "Objective . This study aims at investigating the effects and molecular mechanism of riboflavin-ultraviolet-A-induced cross-linking (corneal collagen cross-linking, CXL) on corneal neovascularization (CNV) in a rabbit alkali burn model. Methods . A total of 60 rabbits were injured with alkali burns to induce CNV in the right eye and were randomly divided into six groups: Group A—injury and no treatment; Groups B, C, and D—CXL treatment for 30 min, 15 min, and 45 min administered immediately after injury, respectively; and Groups E and F—CXL treatment for 30 min administered 1 day and 3 days after injury, respectively. CNV area, corneal edema, and corneal epithelial defects were observed on days 4, 7, 10, and 14 after injury. Western blot was used to detect expression of the vascular endothelial growth factor (VEGF), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-2 (MMP-9), and tissue inhibitor of metalloproteinases 1 (TIMP-1) at 7 and 14 days after injury. Results . CXL treatment decreased CNV and corneal edema in all groups compared to Group A. On day 7, MMP-9 expression was significantly increased in all CXL treatment groups, and TIMP-1 was upregulated in Groups D and F compared to Group A. In addition, VEGF, MMP-2, MMP-9, and TIMP-1 expression were increased in Group A on day 14 after injury. Conclusions . Our results indicate that riboflavin-ultraviolet-A-induced cross-linking (corneal collagen cross-linking, CXL) significantly inhibits alkali burn-induced CNV in rabbits, possibly through downregulating VEGF, MMP-2, MMP-9, and TIMP-1 expression." @default.
• W2896465352 created "2018-10-26" @default.
• W2896465352 creator A5030757374 @default.
• W2896465352 creator A5037574909 @default.
• W2896465352 creator A5061206889 @default.
• W2896465352 date "2018-10-09" @default.
• W2896465352 modified "2023-10-14" @default.
• W2896465352 title "Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits" @default.
• W2896465352 cites W132861023 @default.
• W2896465352 cites W1495820918 @default.
• W2896465352 cites W1606467807 @default.
• W2896465352 cites W1832499168 @default.
• W2896465352 cites W1970480511 @default.
• W2896465352 cites W1983718665 @default.
• W2896465352 cites W2000544973 @default.
• W2896465352 cites W2011909424 @default.
• W2896465352 cites W2029116391 @default.
• W2896465352 cites W2035209150 @default.
• W2896465352 cites W2035377277 @default.
• W2896465352 cites W2045100602 @default.
• W2896465352 cites W2070987864 @default.
• W2896465352 cites W2091583882 @default.
• W2896465352 cites W2095946168 @default.
• W2896465352 cites W2112045938 @default.
• W2896465352 cites W2146401905 @default.
• W2896465352 cites W2343735819 @default.
• W2896465352 cites W2463850935 @default.
• W2896465352 cites W2503268485 @default.
• W2896465352 cites W2534760761 @default.
• W2896465352 cites W2608929622 @default.
• W2896465352 doi "https://doi.org/10.1155/2018/7325483" @default.
• W2896465352 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6198613" @default.
• W2896465352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30402279" @default.
• W2896465352 hasPublicationYear "2018" @default.
• W2896465352 type Work @default.
• W2896465352 sameAs 2896465352 @default.
• W2896465352 citedByCount "6" @default.
• W2896465352 countsByYear W28964653522019 @default.
• W2896465352 countsByYear W28964653522021 @default.
• W2896465352 countsByYear W28964653522022 @default.
• W2896465352 crossrefType "journal-article" @default.
• W2896465352 hasAuthorship W2896465352A5030757374 @default.
• W2896465352 hasAuthorship W2896465352A5037574909 @default.
• W2896465352 hasAuthorship W2896465352A5061206889 @default.
• W2896465352 hasBestOaLocation W28964653521 @default.
• W2896465352 hasConcept C104317684 @default.
• W2896465352 hasConcept C109523444 @default.
• W2896465352 hasConcept C118487528 @default.
• W2896465352 hasConcept C126322002 @default.
• W2896465352 hasConcept C141071460 @default.
• W2896465352 hasConcept C16005928 @default.
• W2896465352 hasConcept C16685009 @default.
• W2896465352 hasConcept C167734588 @default.
• W2896465352 hasConcept C185592680 @default.
• W2896465352 hasConcept C2776155809 @default.
• W2896465352 hasConcept C2776415932 @default.
• W2896465352 hasConcept C2776882836 @default.
• W2896465352 hasConcept C2777025900 @default.
• W2896465352 hasConcept C2777844972 @default.
• W2896465352 hasConcept C2778271429 @default.
• W2896465352 hasConcept C2778918178 @default.
• W2896465352 hasConcept C2779247740 @default.
• W2896465352 hasConcept C2780394083 @default.
• W2896465352 hasConcept C2780886150 @default.
• W2896465352 hasConcept C3017420807 @default.
• W2896465352 hasConcept C55493867 @default.
• W2896465352 hasConcept C71924100 @default.
• W2896465352 hasConceptScore W2896465352C104317684 @default.
• W2896465352 hasConceptScore W2896465352C109523444 @default.
• W2896465352 hasConceptScore W2896465352C118487528 @default.
• W2896465352 hasConceptScore W2896465352C126322002 @default.
• W2896465352 hasConceptScore W2896465352C141071460 @default.
• W2896465352 hasConceptScore W2896465352C16005928 @default.
• W2896465352 hasConceptScore W2896465352C16685009 @default.
• W2896465352 hasConceptScore W2896465352C167734588 @default.
• W2896465352 hasConceptScore W2896465352C185592680 @default.
• W2896465352 hasConceptScore W2896465352C2776155809 @default.
• W2896465352 hasConceptScore W2896465352C2776415932 @default.
• W2896465352 hasConceptScore W2896465352C2776882836 @default.
• W2896465352 hasConceptScore W2896465352C2777025900 @default.
• W2896465352 hasConceptScore W2896465352C2777844972 @default.
• W2896465352 hasConceptScore W2896465352C2778271429 @default.
• W2896465352 hasConceptScore W2896465352C2778918178 @default.
• W2896465352 hasConceptScore W2896465352C2779247740 @default.
• W2896465352 hasConceptScore W2896465352C2780394083 @default.
• W2896465352 hasConceptScore W2896465352C2780886150 @default.
• W2896465352 hasConceptScore W2896465352C3017420807 @default.
• W2896465352 hasConceptScore W2896465352C55493867 @default.
• W2896465352 hasConceptScore W2896465352C71924100 @default.
• W2896465352 hasFunder F4320321001 @default.
• W2896465352 hasLocation W28964653521 @default.
• W2896465352 hasLocation W28964653522 @default.
• W2896465352 hasLocation W28964653523 @default.
• W2896465352 hasLocation W28964653524 @default.
• W2896465352 hasOpenAccess W2896465352 @default.
• W2896465352 hasPrimaryLocation W28964653521 @default.
• W2896465352 hasRelatedWork W2285542579 @default.
• W2896465352 hasRelatedWork W2347845320 @default.

• next