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- W2896489085 abstract "Conducted the detection of genetic polymorphism rs1800471 of TGFb1 gene in unrelated patients of Uzbek nationality with clinically and endoscopically established gastroduodenal diseases, including in patients with diagnosed complicated forms of duodenal ulcer (DU) and chronic gastritis (ChG). It is determined that the carriage of the heterozygous G/C genotype of the TGFb1 gene (rs1800471) is associated with a high risk of development of DU and ChG. It is also revealed that the homozygous genotype G/G possesses a protective anti-inflammatory role in the pathogenesis of ulcerative and inflammatory lesions of the gastric mucosa and duodenum. The burden of unfavorable homozygous genotype C/S in 1.7 and 6.5 times statistically increases the risk of development of DU and ChG, respectively. There were no statistically significant differences between DU and ChG." @default.
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- W2896489085 date "2018-01-01" @default.
- W2896489085 modified "2023-09-27" @default.
- W2896489085 title "Value of the Polymorphism rs1800471 TGFB1 Gene in the Formation of a Predisposition to Duodenal Ulcer and Chronic Gastritis" @default.
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