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• W2896498695 abstract "We recently showed that impaired gait function in adults with cerebral palsy (CP) is associated with reduced rate of force development in ankle dorsiflexors. Here, we explore potential mechanisms. We investigated the suppression of antagonist excitability, calculated as the amount of soleus H-reflex depression at the onset of ankle dorsiflexion compared to rest, in 24 adults with CP (34.3 years, range 18–57; GMFCS 1.95, range 1–3) and 15 healthy, age-matched controls. Furthermore, the central common drive to dorsiflexor motoneurons during a static contraction in the two groups was examined by coherence analyses. The H-reflex was significantly reduced by 37% at the onset of dorsiflexion compared to rest in healthy adults (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.001</mml:mn></mml:math>) but unchanged in adults with CP (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.91</mml:mn></mml:math>). Also, the adults with CP had significantly less coherence. These findings suggest that the ability to suppress antagonist motoneuronal excitability at movement onset is impaired and that the central common drive during static contractions is reduced in adults with CP." @default.
• W2896498695 created "2018-10-26" @default.
• W2896498695 creator A5035393354 @default.
• W2896498695 creator A5054449359 @default.
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• W2896498695 date "2018-10-09" @default.
• W2896498695 modified "2023-10-13" @default.
• W2896498695 title "Impaired Ability to Suppress Excitability of Antagonist Motoneurons at Onset of Dorsiflexion in Adults with Cerebral Palsy" @default.
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• W2896498695 doi "https://doi.org/10.1155/2018/1265143" @default.
• W2896498695 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6198563" @default.
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• W2896498695 hasPublicationYear "2018" @default.
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