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• W2896512461 abstract "Objectives Review of the literature to identify practical, high‐fidelity, commercially available animal models for simulation training and surgical skills maintenance in laryngotracheal reconstruction (LTR). Methods A systematic review of PubMed and Embase databases was conducted independently by two authors, according to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. Search terms included “laryngotracheal reconstruction,” “laryngotracheoplasty,” “pig and larynx,” “sheep and larynx,” and “rabbit and larynx.” Articles were then assessed, identifying model cost and availability, model validation, feasibility as a training tool, and verisimilitude to pediatric LTR. Results In total, 79 articles were considered suitable for inclusion in the study, incorporating both in vitro and in vivo models. Models utilized included rabbit (n = 69), pig (n = 7), sheep (n = 1), and goat (n = 2). The rabbit model was similar in size to the neonate, but differences in laryngeal anatomy and cartilage texture made graft insertion difficult. The anatomy of the pig, sheep, and goat larynges more closely resembled the pediatric patient, allowing improved grafting, but corresponded more in size to that of an older child. Commercial availability of the pig and sheep was considered greatest, and was reflected in cost. None of the animal models identified in the literature have been validated as a simulation tool. Conclusions The rabbit, sheep and pig models seemed to demonstrate the greatest potential for use as advanced pediatric airway surgery simulation models, with the rabbit model being most utilized in the literature. However, as yet there have been no models formally validated as a simulation training tool. Laryngoscope , 129:235–243, 2019" @default.
• W2896512461 created "2018-10-26" @default.
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• W2896512461 date "2018-10-16" @default.
• W2896512461 modified "2023-10-14" @default.
• W2896512461 title "A systematic review of simulated laryngotracheal reconstruction animal models" @default.
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