FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896513495> ?p ?o ?g. }

• W2896513495 endingPage "232" @default.
• W2896513495 startingPage "225" @default.
• W2896513495 abstract "Our aim was to study the regulatory molecule networks involved in the epithelial-to-mesenchymal transition and thus promoting the early onset of metastasis in triple-negative breast cancer (TNBC). Forty pairs of human TNBC and their adjacent normal breast tissues were analyzed by real-time PCR and immunochemistry to demonstrate the correlation between the miR-205 expression and clinicopathological characteristics. In vitro, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide assay, cell migration, and invasion assay were used to detect the cell growth and invasive ability of TNBC cells after upregulation or downregulation of miR-205 expression. Luciferase reporter assay was used to confirm the potential target directly influenced by miR-205. Our results showed that miR-205 abnormal expression may be involved and associated with the biological traits of TNBC. Ectopic expression of miR-205 not only inhibited cell growth, but also suppressed migration and invasion of mesenchymal-like TNBC cells. In addition, we found that overexpression of miR-205 significantly suppressed HMGB1 by binding its 3′-untranslated region, and that miR-205 was inversely correlated with the expression of HMGB1 and RAGE in cell lines and clinical samples. Our study illustrated that miR-205 was a tumor suppressor in TNBC, which attenuated the viability and the acquisition of the epithelial-to-mesenchymal transition phenotype TNBC cells at least partially exerted through targeting of HMGB1–RAGE signaling pathway." @default.
• W2896513495 created "2018-10-26" @default.
• W2896513495 creator A5006434667 @default.
• W2896513495 creator A5018892762 @default.
• W2896513495 creator A5050487837 @default.
• W2896513495 creator A5073888572 @default.
• W2896513495 creator A5080411122 @default.
• W2896513495 date "2019-03-01" @default.
• W2896513495 modified "2023-10-15" @default.
• W2896513495 title "Downregulation of miR-205 contributes to epithelial–mesenchymal transition and invasion in triple-negative breast cancer by targeting HMGB1–RAGE signaling pathway" @default.
• W2896513495 cites W1233074034 @default.
• W2896513495 cites W144423133 @default.
• W2896513495 cites W1630603304 @default.
• W2896513495 cites W1976324983 @default.
• W2896513495 cites W1983991097 @default.
• W2896513495 cites W1989437252 @default.
• W2896513495 cites W1998899716 @default.
• W2896513495 cites W2008239392 @default.
• W2896513495 cites W2014691022 @default.
• W2896513495 cites W2014946489 @default.
• W2896513495 cites W2068172563 @default.
• W2896513495 cites W2078631320 @default.
• W2896513495 cites W2082318061 @default.
• W2896513495 cites W2101136328 @default.
• W2896513495 cites W2102030010 @default.
• W2896513495 cites W2124756133 @default.
• W2896513495 cites W2125120607 @default.
• W2896513495 cites W2128317181 @default.
• W2896513495 cites W2155131748 @default.
• W2896513495 cites W2171608813 @default.
• W2896513495 cites W2335858931 @default.
• W2896513495 cites W2469459870 @default.
• W2896513495 cites W2560480088 @default.
• W2896513495 cites W2595570239 @default.
• W2896513495 cites W2624026115 @default.
• W2896513495 cites W2624781616 @default.
• W2896513495 cites W2724312978 @default.
• W2896513495 cites W2735819991 @default.
• W2896513495 cites W2737876434 @default.
• W2896513495 cites W2743509678 @default.
• W2896513495 cites W2755990808 @default.
• W2896513495 cites W2762716878 @default.
• W2896513495 cites W2763372220 @default.
• W2896513495 cites W2768096340 @default.
• W2896513495 cites W2769011343 @default.
• W2896513495 cites W2769699092 @default.
• W2896513495 cites W2770265911 @default.
• W2896513495 cites W2779944044 @default.
• W2896513495 cites W2783734115 @default.
• W2896513495 cites W2976151714 @default.
• W2896513495 cites W80971072 @default.
• W2896513495 doi "https://doi.org/10.1097/cad.0000000000000705" @default.
• W2896513495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6410973" @default.
• W2896513495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30334817" @default.
• W2896513495 hasPublicationYear "2019" @default.
• W2896513495 type Work @default.
• W2896513495 sameAs 2896513495 @default.
• W2896513495 citedByCount "40" @default.
• W2896513495 countsByYear W28965134952019 @default.
• W2896513495 countsByYear W28965134952020 @default.
• W2896513495 countsByYear W28965134952021 @default.
• W2896513495 countsByYear W28965134952022 @default.
• W2896513495 countsByYear W28965134952023 @default.
• W2896513495 crossrefType "journal-article" @default.
• W2896513495 hasAuthorship W2896513495A5006434667 @default.
• W2896513495 hasAuthorship W2896513495A5018892762 @default.
• W2896513495 hasAuthorship W2896513495A5050487837 @default.
• W2896513495 hasAuthorship W2896513495A5073888572 @default.
• W2896513495 hasAuthorship W2896513495A5080411122 @default.
• W2896513495 hasBestOaLocation W28965134952 @default.
• W2896513495 hasConcept C104317684 @default.
• W2896513495 hasConcept C121608353 @default.
• W2896513495 hasConcept C127561419 @default.
• W2896513495 hasConcept C137738243 @default.
• W2896513495 hasConcept C145059251 @default.
• W2896513495 hasConcept C1491633281 @default.
• W2896513495 hasConcept C169760540 @default.
• W2896513495 hasConcept C185592680 @default.
• W2896513495 hasConcept C198826908 @default.
• W2896513495 hasConcept C2778857457 @default.
• W2896513495 hasConcept C2779013556 @default.
• W2896513495 hasConcept C2780110267 @default.
• W2896513495 hasConcept C2780932548 @default.
• W2896513495 hasConcept C502942594 @default.
• W2896513495 hasConcept C530470458 @default.
• W2896513495 hasConcept C54355233 @default.
• W2896513495 hasConcept C55493867 @default.
• W2896513495 hasConcept C76419328 @default.
• W2896513495 hasConcept C81885089 @default.
• W2896513495 hasConcept C86803240 @default.
• W2896513495 hasConcept C95444343 @default.
• W2896513495 hasConcept C97037327 @default.
• W2896513495 hasConceptScore W2896513495C104317684 @default.
• W2896513495 hasConceptScore W2896513495C121608353 @default.
• W2896513495 hasConceptScore W2896513495C127561419 @default.
• W2896513495 hasConceptScore W2896513495C137738243 @default.
• W2896513495 hasConceptScore W2896513495C145059251 @default.
• W2896513495 hasConceptScore W2896513495C1491633281 @default.

• next