FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896517039> ?p ?o ?g. }

• W2896517039 endingPage "1480" @default.
• W2896517039 startingPage "1471" @default.
• W2896517039 abstract "The principal mechanism of reducing sulfur into organic compounds is via the synthesis of l-cysteine. Cysteine is used for protein and glutathione synthesis, as well as being the primary sulfur source for a variety of other molecules, such as biotin, coenzyme A, lipoic acid and more. Glutathione and other cysteine derivatives are important for protection against the oxidative stress that pathogenic bacteria such as Neisseria gonorrhoeae and Neisseria meningitidis encounter during infection. With the alarming rise of antibiotic-resistant strains of N. gonorrhoeae, the development of inhibitors for the future treatment of this disease is critical, and targeting cysteine biosynthesis enzymes could be a promising approach for this. Little is known about the transport of sulfate and thiosulfate and subsequent sulfate reduction and incorporation into cysteine in Neisseria species. In this review we investigate cysteine biosynthesis within Neisseria species and examine the differences between species and with other bacteria. Neisseria species exhibit different arrangements of cysteine biosynthesis genes and have slight differences in how they assimilate sulfate and synthesize cysteine, while, most interestingly, N. gonorrhoeae by virtue of a genome deletion, lacks the ability to reduce sulfate to bisulfide for incorporation into cysteine, and as such uses the thiosulfate uptake pathway for the synthesis of cysteine." @default.
• W2896517039 created "2018-10-26" @default.
• W2896517039 creator A5015198691 @default.
• W2896517039 creator A5088053405 @default.
• W2896517039 date "2018-12-01" @default.
• W2896517039 modified "2023-10-14" @default.
• W2896517039 title "Cysteine biosynthesis in Neisseria species" @default.
• W2896517039 cites W1507857421 @default.
• W2896517039 cites W1571136093 @default.
• W2896517039 cites W1608423741 @default.
• W2896517039 cites W1612597812 @default.
• W2896517039 cites W1624182167 @default.
• W2896517039 cites W1803102843 @default.
• W2896517039 cites W1854671426 @default.
• W2896517039 cites W1909647962 @default.
• W2896517039 cites W1932279726 @default.
• W2896517039 cites W1942931565 @default.
• W2896517039 cites W1969846013 @default.
• W2896517039 cites W1974844310 @default.
• W2896517039 cites W1979149597 @default.
• W2896517039 cites W1980751665 @default.
• W2896517039 cites W2002028845 @default.
• W2896517039 cites W2002423236 @default.
• W2896517039 cites W2002766407 @default.
• W2896517039 cites W2003299945 @default.
• W2896517039 cites W2007097682 @default.
• W2896517039 cites W2007754595 @default.
• W2896517039 cites W2015826900 @default.
• W2896517039 cites W2022339517 @default.
• W2896517039 cites W2029443025 @default.
• W2896517039 cites W2036735937 @default.
• W2896517039 cites W2039837799 @default.
• W2896517039 cites W2041587858 @default.
• W2896517039 cites W2049474456 @default.
• W2896517039 cites W2049908836 @default.
• W2896517039 cites W2053264108 @default.
• W2896517039 cites W2063750342 @default.
• W2896517039 cites W2066821926 @default.
• W2896517039 cites W2069332918 @default.
• W2896517039 cites W2074951455 @default.
• W2896517039 cites W2095924770 @default.
• W2896517039 cites W2101417771 @default.
• W2896517039 cites W2101587094 @default.
• W2896517039 cites W2103812049 @default.
• W2896517039 cites W2104743763 @default.
• W2896517039 cites W2110767136 @default.
• W2896517039 cites W2111940505 @default.
• W2896517039 cites W2117832633 @default.
• W2896517039 cites W2117868485 @default.
• W2896517039 cites W2121934427 @default.
• W2896517039 cites W2124804993 @default.
• W2896517039 cites W2127335580 @default.
• W2896517039 cites W2128879290 @default.
• W2896517039 cites W2134898567 @default.
• W2896517039 cites W2136358591 @default.
• W2896517039 cites W2136559966 @default.
• W2896517039 cites W2137873626 @default.
• W2896517039 cites W2139419458 @default.
• W2896517039 cites W2162376892 @default.
• W2896517039 cites W2224056471 @default.
• W2896517039 cites W2225586700 @default.
• W2896517039 cites W2315184619 @default.
• W2896517039 cites W2468585132 @default.
• W2896517039 cites W2506254155 @default.
• W2896517039 cites W2725319213 @default.
• W2896517039 cites W4249066710 @default.
• W2896517039 cites W2062965299 @default.
• W2896517039 doi "https://doi.org/10.1099/mic.0.000728" @default.
• W2896517039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30307392" @default.
• W2896517039 hasPublicationYear "2018" @default.
• W2896517039 type Work @default.
• W2896517039 sameAs 2896517039 @default.
• W2896517039 citedByCount "16" @default.
• W2896517039 countsByYear W28965170392019 @default.
• W2896517039 countsByYear W28965170392020 @default.
• W2896517039 countsByYear W28965170392021 @default.
• W2896517039 countsByYear W28965170392022 @default.
• W2896517039 countsByYear W28965170392023 @default.
• W2896517039 crossrefType "journal-article" @default.
• W2896517039 hasAuthorship W2896517039A5015198691 @default.
• W2896517039 hasAuthorship W2896517039A5088053405 @default.
• W2896517039 hasBestOaLocation W28965170391 @default.
• W2896517039 hasConcept C178790620 @default.
• W2896517039 hasConcept C181199279 @default.
• W2896517039 hasConcept C185592680 @default.
• W2896517039 hasConcept C2779166590 @default.
• W2896517039 hasConcept C2779201268 @default.
• W2896517039 hasConcept C2779268744 @default.
• W2896517039 hasConcept C515207424 @default.
• W2896517039 hasConcept C518881349 @default.
• W2896517039 hasConcept C538909803 @default.
• W2896517039 hasConcept C553450214 @default.
• W2896517039 hasConcept C55493867 @default.
• W2896517039 hasConcept C86803240 @default.
• W2896517039 hasConcept C89423630 @default.
• W2896517039 hasConceptScore W2896517039C178790620 @default.
• W2896517039 hasConceptScore W2896517039C181199279 @default.
• W2896517039 hasConceptScore W2896517039C185592680 @default.

• next