Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896524701> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2896524701 endingPage "1969" @default.
- W2896524701 startingPage "1965" @default.
- W2896524701 abstract "Background: Babesiosis caused by Babesia gibsoni is recognized throughout the world and can be difficult to treat. Resistance to atovaquone is associated with mutations in the B. gibsoni mitochondrial genome, specifically the M128 position of cytochrome b ( cytb ). The prevalence of cytb mutations in North America has not been reported. Hypothesis/Objectives: The objective of our study was to describe the prevalence of cytb M128 mutations in B. gibsoni in canine blood samples submitted to a US veterinary diagnostic laboratory. A secondary objective was to determine whether or not some dogs had wild‐type cytb in our initial samples then had M128 mutations detected in follow‐up samples. Animals: One‐Hundred seventy‐four dogs that tested positive for the presence of B. gibsoni between 2012 and 2017. Methods: Case series of consecutive samples submitted to a veterinary diagnostic laboratory. Partial B. gibsoni cytb genes were amplified by polymerase chain reaction and screened for the presence of mutations at the M128 position. Results: The overall prevalence of M128 mutants was 3.5% (6/173 dogs) in the initial samples. The incidence of new cytb mutants in dogs that tested positive for B. gibsoni , which then had follow‐up testing, was 12.1% (5/41). Conclusions and Clinic Importance: Our study reaffirms that B. gibsoni infection is widespread and most commonly detected in American Staffordshire Terrier/American Pit Bull Terrier dogs (128/174, 74% of the infected dogs in our study). The prevalence of cytb mutations does not warrant pretreatment genotyping." @default.
- W2896524701 created "2018-10-26" @default.
- W2896524701 creator A5042094023 @default.
- W2896524701 creator A5054517162 @default.
- W2896524701 creator A5068422382 @default.
- W2896524701 creator A5089655675 @default.
- W2896524701 creator A5090247578 @default.
- W2896524701 date "2018-10-11" @default.
- W2896524701 modified "2023-09-25" @default.
- W2896524701 title "<i>Babesia gibsoni</i> cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory" @default.
- W2896524701 cites W2006976509 @default.
- W2896524701 cites W2041795310 @default.
- W2896524701 cites W2090782110 @default.
- W2896524701 cites W2093221196 @default.
- W2896524701 cites W2095236461 @default.
- W2896524701 cites W2099607047 @default.
- W2896524701 cites W2106362699 @default.
- W2896524701 cites W2117089016 @default.
- W2896524701 cites W2158489405 @default.
- W2896524701 cites W2264597168 @default.
- W2896524701 cites W2441043810 @default.
- W2896524701 cites W2594293670 @default.
- W2896524701 cites W2626723996 @default.
- W2896524701 cites W4255614620 @default.
- W2896524701 cites W4361867863 @default.
- W2896524701 cites W2742102967 @default.
- W2896524701 doi "https://doi.org/10.1111/jvim.15300" @default.
- W2896524701 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6272040" @default.
- W2896524701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30307644" @default.
- W2896524701 hasPublicationYear "2018" @default.
- W2896524701 type Work @default.
- W2896524701 sameAs 2896524701 @default.
- W2896524701 citedByCount "7" @default.
- W2896524701 countsByYear W28965247012020 @default.
- W2896524701 countsByYear W28965247012021 @default.
- W2896524701 countsByYear W28965247012022 @default.
- W2896524701 crossrefType "journal-article" @default.
- W2896524701 hasAuthorship W2896524701A5042094023 @default.
- W2896524701 hasAuthorship W2896524701A5054517162 @default.
- W2896524701 hasAuthorship W2896524701A5068422382 @default.
- W2896524701 hasAuthorship W2896524701A5089655675 @default.
- W2896524701 hasAuthorship W2896524701A5090247578 @default.
- W2896524701 hasBestOaLocation W28965247011 @default.
- W2896524701 hasConcept C104317684 @default.
- W2896524701 hasConcept C135763542 @default.
- W2896524701 hasConcept C142724271 @default.
- W2896524701 hasConcept C148292235 @default.
- W2896524701 hasConcept C24586158 @default.
- W2896524701 hasConcept C2778048844 @default.
- W2896524701 hasConcept C2778145968 @default.
- W2896524701 hasConcept C2778371730 @default.
- W2896524701 hasConcept C2779124865 @default.
- W2896524701 hasConcept C2780581805 @default.
- W2896524701 hasConcept C31467283 @default.
- W2896524701 hasConcept C42972112 @default.
- W2896524701 hasConcept C49105822 @default.
- W2896524701 hasConcept C54355233 @default.
- W2896524701 hasConcept C71924100 @default.
- W2896524701 hasConcept C86803240 @default.
- W2896524701 hasConceptScore W2896524701C104317684 @default.
- W2896524701 hasConceptScore W2896524701C135763542 @default.
- W2896524701 hasConceptScore W2896524701C142724271 @default.
- W2896524701 hasConceptScore W2896524701C148292235 @default.
- W2896524701 hasConceptScore W2896524701C24586158 @default.
- W2896524701 hasConceptScore W2896524701C2778048844 @default.
- W2896524701 hasConceptScore W2896524701C2778145968 @default.
- W2896524701 hasConceptScore W2896524701C2778371730 @default.
- W2896524701 hasConceptScore W2896524701C2779124865 @default.
- W2896524701 hasConceptScore W2896524701C2780581805 @default.
- W2896524701 hasConceptScore W2896524701C31467283 @default.
- W2896524701 hasConceptScore W2896524701C42972112 @default.
- W2896524701 hasConceptScore W2896524701C49105822 @default.
- W2896524701 hasConceptScore W2896524701C54355233 @default.
- W2896524701 hasConceptScore W2896524701C71924100 @default.
- W2896524701 hasConceptScore W2896524701C86803240 @default.
- W2896524701 hasIssue "6" @default.
- W2896524701 hasLocation W28965247011 @default.
- W2896524701 hasLocation W28965247012 @default.
- W2896524701 hasLocation W28965247013 @default.
- W2896524701 hasOpenAccess W2896524701 @default.
- W2896524701 hasPrimaryLocation W28965247011 @default.
- W2896524701 hasRelatedWork W2050459405 @default.
- W2896524701 hasRelatedWork W2062498483 @default.
- W2896524701 hasRelatedWork W2404958601 @default.
- W2896524701 hasRelatedWork W2791910957 @default.
- W2896524701 hasRelatedWork W3197010027 @default.
- W2896524701 hasRelatedWork W3200888103 @default.
- W2896524701 hasRelatedWork W4211025802 @default.
- W2896524701 hasRelatedWork W4255614620 @default.
- W2896524701 hasRelatedWork W4295956985 @default.
- W2896524701 hasRelatedWork W4313451741 @default.
- W2896524701 hasVolume "32" @default.
- W2896524701 isParatext "false" @default.
- W2896524701 isRetracted "false" @default.
- W2896524701 magId "2896524701" @default.
- W2896524701 workType "article" @default.