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• W2896530812 abstract "Abstract Photocontrolled, targeted and biocompatible supramolecular nanoparticles were constructed through the host‐guest interactions of 2‐nitrobenzyl ester‐linked β‐cyclodextrin and adamantane‐grafted hyaluronic acid (HA). In this system, we used HA and 2‐nitrobenzyl ester as targeting and photoresponsive groups, respectively. Moreover, the introduction of β‐cyclodextrin further enhanced the biocompatibility of the supramolecular nanoparticles. Benefiting from the light‐responsive capability of a 2‐nitrobenzyl ester moiety, the hydrophobic anticancer drug camptothecin was loaded in the internal hydrophobic microenvironment of the supramolecular nanoparticle and could be specifically released in the cancer cells. These results demonstrated that supramolecular polysaccharide drug nanocarriers with targeting ability and intelligent light‐stimulus responsiveness may have excellent potential in the clinical cancer treatments." @default.
• W2896530812 created "2018-10-26" @default.
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• W2896530812 date "2018-10-31" @default.
• W2896530812 modified "2023-10-14" @default.
• W2896530812 title "Photocleavable Supramolecular Polysaccharide Nanoparticles for Targeted Drug Release in Cancer Cells" @default.
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• W2896530812 doi "https://doi.org/10.1002/ajoc.201800552" @default.
• W2896530812 hasPublicationYear "2018" @default.
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