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- W2896533384 abstract "Objective: The objective of this study is to evaluate the prevalence and influence on outcome of cardiac abnormalities in intracerebral hemorrhage (ICH). Background: Cardiac assessment is recommended for patients with ICH. However, the yield and significance of this workup is unclear. Design/Methods: Retrospective data from 145 consecutive patients with spontaneous supratentorial ICH admitted to a large university hospital were included in this study. CT scans were reviewed to determine location and hematoma volume. Patients with history of myocardial infarction or congestive heart failure were excluded. Transthoracic echocardiography (TTE) reports were reviewed for motion wall abnormalities (hypokinesia, akinesia or dyskinesia) and depressed ejection fraction (EF Results: Median age was 55 years [Interquartile Range (IQR) (47–66)] and 49% were female. Median ICH score was 1 [IQR (1–3)]. Median Glasgow come scale (GCS) on admission was 14 [IQR (8–15)]. cTnI levels were available in 127 cases and TTE data in 78 cases. Elevated cTnI was observed in 47% of cases. 49% had wall motion abnormalities and 20.5% had depressed EF. A significant regression equation was found: F (2, 124) = 35.7, p 2 of .366, where troponin level had a significant positive regression weight (B=0.377), indicating that patients with increasing levels of troponins were expected to have worse outcome. Only cTnI levels ≥0.092 ng/mL were associated with poor outcome after controlling for ICH score (p=0.028). In contrast, TTE abnormalities did not affect outcome. Conclusions: Prevalence of cardiac abnormalities is elevated in ICH patients. Early cTnI elevation predicts poor outcome at hospital discharge. Disclosure: Dr. Trifan has nothing to disclose. Dr. Guman has nothing to disclose. Dr Testai has nothing to disclose." @default.
- W2896533384 created "2018-10-26" @default.
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- W2896533384 date "2018-04-10" @default.
- W2896533384 modified "2023-09-26" @default.
- W2896533384 title "Elevated Serum Troponin Levels Predict Worse Outcome After Intracerebral Hemorrhage (P1.248)" @default.
- W2896533384 hasPublicationYear "2018" @default.
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