Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896581357> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2896581357 endingPage "4909" @default.
- W2896581357 startingPage "4904" @default.
- W2896581357 abstract "Herein we describe the 2,2,2-trifluoroethoxy group as an alternative leaving group for hydrolytically unstable heteroaryl chlorides. This group provides improved shelf stability by years while maintaining reactivity toward nucleophiles in SNAr reactions. A highlighted trifluoroethyl ether was shown to be tolerant to aqueous Suzuki conditions, permitting sequential Suzuki/SNAr processes inaccessible to the heterocyclic chlorides. The strategic use of trifluoroethyl ethers enables storage of otherwise unstable heterocyclic chlorides and limits costly decomposition." @default.
- W2896581357 created "2018-10-26" @default.
- W2896581357 creator A5018013677 @default.
- W2896581357 creator A5044115787 @default.
- W2896581357 creator A5059166433 @default.
- W2896581357 date "2018-10-19" @default.
- W2896581357 modified "2023-10-12" @default.
- W2896581357 title "2,2,2-Trifluoroethoxy Aromatic Heterocycles: Hydrolytically Stable Alternatives to Heteroaryl Chlorides" @default.
- W2896581357 cites W1044925281 @default.
- W2896581357 cites W2010037381 @default.
- W2896581357 cites W2017565332 @default.
- W2896581357 cites W2047105753 @default.
- W2896581357 cites W2055426491 @default.
- W2896581357 cites W2083029364 @default.
- W2896581357 cites W2147479105 @default.
- W2896581357 cites W2247581895 @default.
- W2896581357 cites W2344164078 @default.
- W2896581357 cites W2771967444 @default.
- W2896581357 cites W2777092594 @default.
- W2896581357 cites W2801201828 @default.
- W2896581357 cites W2952271840 @default.
- W2896581357 doi "https://doi.org/10.1021/acs.joc.8b02453" @default.
- W2896581357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30339369" @default.
- W2896581357 hasPublicationYear "2018" @default.
- W2896581357 type Work @default.
- W2896581357 sameAs 2896581357 @default.
- W2896581357 citedByCount "6" @default.
- W2896581357 countsByYear W28965813572019 @default.
- W2896581357 countsByYear W28965813572020 @default.
- W2896581357 countsByYear W28965813572021 @default.
- W2896581357 countsByYear W28965813572022 @default.
- W2896581357 countsByYear W28965813572023 @default.
- W2896581357 crossrefType "journal-article" @default.
- W2896581357 hasAuthorship W2896581357A5018013677 @default.
- W2896581357 hasAuthorship W2896581357A5044115787 @default.
- W2896581357 hasAuthorship W2896581357A5059166433 @default.
- W2896581357 hasConcept C135731615 @default.
- W2896581357 hasConcept C142724271 @default.
- W2896581357 hasConcept C160964918 @default.
- W2896581357 hasConcept C161790260 @default.
- W2896581357 hasConcept C178790620 @default.
- W2896581357 hasConcept C178907741 @default.
- W2896581357 hasConcept C185592680 @default.
- W2896581357 hasConcept C204787440 @default.
- W2896581357 hasConcept C21951064 @default.
- W2896581357 hasConcept C2776910235 @default.
- W2896581357 hasConcept C2780407432 @default.
- W2896581357 hasConcept C71924100 @default.
- W2896581357 hasConcept C9061509 @default.
- W2896581357 hasConceptScore W2896581357C135731615 @default.
- W2896581357 hasConceptScore W2896581357C142724271 @default.
- W2896581357 hasConceptScore W2896581357C160964918 @default.
- W2896581357 hasConceptScore W2896581357C161790260 @default.
- W2896581357 hasConceptScore W2896581357C178790620 @default.
- W2896581357 hasConceptScore W2896581357C178907741 @default.
- W2896581357 hasConceptScore W2896581357C185592680 @default.
- W2896581357 hasConceptScore W2896581357C204787440 @default.
- W2896581357 hasConceptScore W2896581357C21951064 @default.
- W2896581357 hasConceptScore W2896581357C2776910235 @default.
- W2896581357 hasConceptScore W2896581357C2780407432 @default.
- W2896581357 hasConceptScore W2896581357C71924100 @default.
- W2896581357 hasConceptScore W2896581357C9061509 @default.
- W2896581357 hasIssue "8" @default.
- W2896581357 hasLocation W28965813571 @default.
- W2896581357 hasLocation W28965813572 @default.
- W2896581357 hasOpenAccess W2896581357 @default.
- W2896581357 hasPrimaryLocation W28965813571 @default.
- W2896581357 hasRelatedWork W1559171237 @default.
- W2896581357 hasRelatedWork W2010288151 @default.
- W2896581357 hasRelatedWork W2023790188 @default.
- W2896581357 hasRelatedWork W2073575063 @default.
- W2896581357 hasRelatedWork W2115390529 @default.
- W2896581357 hasRelatedWork W2491347897 @default.
- W2896581357 hasRelatedWork W2910858533 @default.
- W2896581357 hasRelatedWork W2949260533 @default.
- W2896581357 hasRelatedWork W2950536131 @default.
- W2896581357 hasRelatedWork W2951977816 @default.
- W2896581357 hasVolume "84" @default.
- W2896581357 isParatext "false" @default.
- W2896581357 isRetracted "false" @default.
- W2896581357 magId "2896581357" @default.
- W2896581357 workType "article" @default.